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What is Fluocinonide
FluocinonideThe Generic name of this drug
Treatment SummaryA topical steroid used to reduce inflammation and treat eczema.
Fluocinonideis the brand name
Fluocinonide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fluocinonide
Fluocinonide
1984
147
Approved as Treatment by the FDA
Fluocinonide, otherwise known as Fluocinonide, is approved by the FDA for 3 uses like Dermatosis and Inflammation .Dermatosis
Used to treat Dermatosis in combination with Gramicidin D
Inflammation
Used to treat Inflammation in combination with Gramicidin D
Itching
Used to treat Pruritus in combination with Gramicidin D
Effectiveness
How Fluocinonide Affects PatientsFluocinonide is a strong medicine used to reduce inflammation and treat skin conditions like eczema. It helps reduce itching, redness, dryness, crusting, scaling, inflammation, and other discomforts caused by skin inflammation.
How Fluocinonide works in the bodyFluocinonide is a steroid used to reduce inflammation in the skin. It binds to a receptor in the cell nucleus and causes changes in gene expression. Fluocinonide works by blocking the production of substances called prostaglandins and leukotrienes, which are responsible for inflammation. It also blocks the action of certain proteins that help cells stick together and move around. The steroid also weakens the immune system by reducing lymphocytes and other immune system components. Finally, it interferes with the body's ability to create and use energy, leading to increased glucose levels in the blood.
When to interrupt dosage
The prescribed dosage of Fluocinonide is contingent upon the determined condition, including Inflammation, Dermatosis and Itch. The amount of dosage likewise varies, in accordance with the technique of delivery (e.g. Topical or Jelly - Topical) featured in the table beneath.Condition
Dosage
Administration
Dermatosis
, 0.0005 mg/mg, 0.5 mg/mL, 0.001 mg/mg, 0.05 %, 0.01 %, 0.00005 mg/mg
, Topical, Gel, Gel - Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Solution, Solution - Topical, Jelly, Jelly - Topical, Cream; Emulsion, Cream; Emulsion - Topical, Kit - Topical, Kit
Itching
, 0.0005 mg/mg, 0.5 mg/mL, 0.001 mg/mg, 0.05 %, 0.01 %, 0.00005 mg/mg
, Topical, Gel, Gel - Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Solution, Solution - Topical, Jelly, Jelly - Topical, Cream; Emulsion, Cream; Emulsion - Topical, Kit - Topical, Kit
Inflammation
, 0.0005 mg/mg, 0.5 mg/mL, 0.001 mg/mg, 0.05 %, 0.01 %, 0.00005 mg/mg
, Topical, Gel, Gel - Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Solution, Solution - Topical, Jelly, Jelly - Topical, Cream; Emulsion, Cream; Emulsion - Topical, Kit - Topical, Kit
Warnings
There are 20 known major drug interactions with Fluocinonide.Common Fluocinonide Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with Abatacept.
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Fluocinonide.
Abetimus
Major
The risk or severity of adverse effects can be increased when Fluocinonide is combined with Abetimus.
Fluocinonide Toxicity & Overdose RiskPossible side effects of using this drug include acne, burning sensation, dry skin, increased hair growth, skin infections, irritation, itching, discoloration, heat rash, inflammation, skin thinning or softening, and stretch marks.
Fluocinonide Novel Uses: Which Conditions Have a Clinical Trial Featuring Fluocinonide?
Currently, 200 active clinical trials are assessing the potential of Fluocinonide to alleviate Itch, Inflammation and Dermatosis.Condition
Clinical Trials
Trial Phases
Itching
10 Actively Recruiting
Phase 4, Phase 3, Phase 2, Phase 1
Dermatosis
0 Actively Recruiting
Inflammation
169 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Fluocinonide Reviews: What are patients saying about Fluocinonide?
5Patient Review
6/24/2017 This solution is essential to my life. I have scalp psoriasis and it's the only thing that works for me. It might burn at first, but soon enough you'll start noticing a difference.
5Patient Review
10/24/2017 This cream quickly and effectively relieved both my chigger bites and the rash that developed from sweating and friction.
5Patient Review
2/5/2021 This ointment, prescribed by my podiatrist has done an excellent job of clearing up my foot fungus. However, it hasn't cured the problem entirely. I'm also not a fan of ointments in general, so that's why it only gets four stars from me.
5Patient Review
3/27/2019 I've been using this for years with great success. Whenever I have an area of severe itching, I apply a thin film and the sensation subsides within hours - it never returns!
5Patient Review
5/15/2016 This medication has been working wonders for my eczema. It cleared up the rash within just a couple of days, and if I start to feel an itch coming on, I can apply it and prevent the redness and blisters from even forming. I'm really amazed at how well this medication works!
4Patient Review
5/2/2017 While this medication did clear the redness, I found myself feeling really down and depressed. This was strange and surprising to me, so I wanted to warn others in case this could be a more serious side effect for someone with an underlying condition.
2.7Patient Review
12/10/2017 It's hard to use this treatment by yourself, but it did clear up my scalp psoriasis. However, the symptoms came back after I stopped using it for a week. Another downside is that I experienced a lot of hair loss.
2.7Patient Review
8/23/2021 I didn't see any reduction in itchiness when using this cream, unfortunately.
2.3Patient Review
3/30/2018 I was admitted to the hospital for cellulitis on my arm and then started breaking out with an itchy rash. I have been to four different doctors, and one prescribed medication for a fungus under my nails which I didn't have. I am hoping that this cream will work because the itch is driving me insane. It's spreading from my armpits to my chest, between my legs, and up my neck. The instructions say not to use it on your armpits, but it seems to be worse in areas that are moist. If anyone has any advice, please let me know.
2.3Patient Review
3/22/2019 I was really hoping this would help me more than it did. It's not that it didn't work at all, but I still have a long way to go before finding something that completely eliminates my itchiness.
1Patient Review
8/22/2017 I started taking this medication and - while it did stop the severe itching I was experiencing from eczema - it caused huge, pus-filled bumps that were incredibly inflamed. My face also broke out in terrible acne. Needless to say, I stopped taking this medication.
1Patient Review
1/6/2021 The 0.01% concentration didn't help me at all. I'm wondering if a stronger dose would've made a difference.
Patient Q&A Section about fluocinonide
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is fluocinonide cream an antifungal?
"No, fluocinonide (Vanos) is not an antifungal medication. It is a corticosteroid. Depending on your personal skin condition, you might be prescribed fluocinonide (Vanos) and an antifungal at the same time."
Answered by AI
What are side effects of fluocinonide?
"Possible side effects of the medication include: painful and/or itchy skin, soreness, redness and scaling around the mouth, and severe burning, crusting, or flaking of the skin."
Answered by AI