Your session is about to expire
What is Fenoglide
FenofibrateThe Generic name of this drug
Treatment SummaryFenofibrate is a medication used to lower cholesterol and triglycerides in people with primary hypercholesterolemia, mixed dyslipidemia, and severe hypertriglyceridemia. It was approved by the FDA in 1993 and is similar to other medications such as clofibrate and gemfibrozil.
Tricoris the brand name
Fenoglide Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tricor
Fenofibrate
2002
421
Approved as Treatment by the FDA
Fenofibrate, also known as Tricor, is approved by the FDA for 5 uses which include Hypertriglyceridemia and Primary Hypercholesterolemia .Hypertriglyceridemia
Primary Hypercholesterolemia
Dyslipidemias
Hypertriglyceridemia
severe Fredrickson Type V Hypertriglyceridemia
Effectiveness
How Fenoglide Affects PatientsFenofibrate is a type of medication that helps your body manage cholesterol and triglyceride levels. It is usually taken once a day, and its effects last for 19-27 hours. A proper dose of fenofibrate is typically between 50-150mg per day. Patients should be aware of the potential risks of taking this drug, such as rhabdomyolysis, myopathy and cholelithiasis.
How Fenoglide works in the bodyFenofibrate increases the body's ability to break down fats. It does this by activating a protein called PPARα. When this protein is turned on, more molecules are produced that help break down fat. This process can be hard on the liver, and in rare cases can cause cirrhosis or chronic active hepatitis.
When to interrupt dosage
The suggested measure of Fenoglide is influenced by the diagnosed state, for example, grave Fredrickson Type V Hypertriglyceridemia, Dyslipidemias and Hypertriglyceridemia. The magnitude of dosage shifts according to the approach of delivery (e.g. Oral or Tablet, film coated) provided in the subsequent table.Condition
Dosage
Administration
Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
severe Fredrickson Type V Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Primary Hypercholesterolemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Dyslipidemias
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
Fenoglide has three contraindications, so it should not be consumed while suffering from the ailments detailed in the following table.Fenoglide ContraindicationsCondition
Risk Level
Notes
active liver disease
Do Not Combine
Gall Bladder Diseases
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Fenofibrate may interact with Pulse Frequency
Common Fenoglide Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Fenofibrate.
Aluminium clofibrate
Major
The risk or severity of adverse effects can be increased when Fenofibrate is combined with Aluminium clofibrate.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Fenofibrate.
Bezafibrate
Major
The risk or severity of adverse effects can be increased when Fenofibrate is combined with Bezafibrate.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Fenofibrate.
Fenoglide Toxicity & Overdose RiskThe lowest toxic dose of fenofibrate in rats is greater than 2g/kg and 1600mg/kg in mice. To treat an overdose, supportive care such as monitoring vital signs and observing the patient's condition is recommended. Vomiting or stomach pumping may be used to remove the drug from the body, however dialysis is not expected to be useful since fenofibrate binds to proteins.
Fenoglide Novel Uses: Which Conditions Have a Clinical Trial Featuring Fenoglide?
At present, 15 active trials are investigating the potential of Fenoglide to mitigate severe Fredrickson Type V Hypertriglyceridemia, Hypertriglyceridemia and Dyslipidemias.Condition
Clinical Trials
Trial Phases
Dyslipidemias
1 Actively Recruiting
Phase 2
severe Fredrickson Type V Hypertriglyceridemia
0 Actively Recruiting
Hypertriglyceridemia
0 Actively Recruiting
Hypertriglyceridemia
4 Actively Recruiting
Phase 3
Primary Hypercholesterolemia
16 Actively Recruiting
Early Phase 1, Not Applicable, Phase 3, Phase 2
Fenoglide Reviews: What are patients saying about Fenoglide?
5Patient Review
12/5/20085Patient Review
3/15/20105Patient Review
9/15/20105Patient Review
10/25/20105Patient Review
4/20/2016 I'm taking the tablet form of this medication, but I would prefer capsules.
5Patient Review
1/30/2011 I unfortunately had to stop taking this medication after only two days due to incredibly severe nausea and upset stomach. I also have acid reflux, so it's possible that the two medications didn't mix well.
5Patient Review
1/30/2012 This treatment lowered my triglyceride levels by more than 50% and improved my high density cholesterol by 20%.
3.7Patient Review
1/11/20103.7Patient Review
8/18/2017 When I started this treatment, my triglyceride level was 477. Six months later, it had decreased to 176. I'm really amazed by the results.
3Patient Review
10/3/2012 I've been taking this medication for a little while now and have definitely seen an improvement in my triglyceride levels.
2.3Patient Review
1/13/2014 My health has declined since taking this treatment.
2.3Patient Review
12/3/2013 This drug has been a lifesaver! My triglycerides were 1160 four months ago, and now they're down to 120. My cholesterol was 474 and is now 157. When combined with diet and exercise, this medication really helped lower my numbers.
1Patient Review
10/8/2009Patient Q&A Section about fenoglide
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How does fenofibrate work?
"Fenofibrate is used to lower bad cholesterol and fats by increasing the natural substance that breaks down fats."
Answered by AI
What is the brand name for fenofibrate?
"Fenofibrate is a drug used to treat high cholesterol levels. It comes in the form of an oral tablet or oral capsule. The brand names for fenofibrate are Fenoglide, Tricor, and Triglide."
Answered by AI
What are the side effects of fenofibrate 145 mg?
"Liver function may increase with this medication, as well as respiratory and abdominal pain. There is also the potential for back pain, increased CPK, headaches, constipation, and nausea."
Answered by AI
What is fenoglide used for?
"Fenoglide (fenofibrate) is a drug that helps regulate lipids like cholesterol and triglycerides in the blood. It is used to treat high levels of cholesterol and triglycerides."
Answered by AI