What is Feldene
PiroxicamThe Generic name of this drug
Treatment SummaryIbuprofen is a type of medication that reduces inflammation and pain. It is commonly used to treat conditions such as rheumatoid arthritis, osteoarthritis, and other musculoskeletal disorders. Ibuprofen can also be used to treat menstrual cramps and post-surgery pain. It has a long-lasting effect, so it only needs to be taken once a day.
Piroxicamis the brand name
Feldene Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Piroxicam
Piroxicam
1993
85
Approved as Treatment by the FDA
Piroxicam, also known as Piroxicam, is approved by the FDA for 3 uses such as Osteoarthritis (OA) and Ankylosing Spondylitis .Osteoarthritis (OA)
Ankylosing Spondylitis
Rheumatoid Arthritis
Effectiveness
How Feldene Affects PatientsPiroxicam is a type of medicine called a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the hormones that cause pain and inflammation in the body. It is used to help relieve pain, swelling and stiffness caused by rheumatoid arthritis and osteoarthritis.
How Feldene works in the bodyPiroxicam reduces inflammation by blocking an enzyme called Cox-1. This enzyme is responsible for producing prostaglandins, which are chemicals that cause inflammation. Piroxicam also prevents white blood cells from entering sites of inflammation and stops platelets from making a chemical that causes clots.
When to interrupt dosage
The suggested dosage of Feldene is contingent upon the diagnosed condition, including Osteoarthritis (OA), Rheumatoid Arthritis and Ankylosing Spondylitis. The amount of dosage varies as per the technique of delivery (e.g. Rectal or Suppository) portrayed in the table beneath.Condition
Dosage
Administration
Ankylosing Spondylitis
, 20.0 mg, 10.0 mg
Rectal, Suppository, Suppository - Rectal, Capsule, Capsule - Oral, Tablet, , Tablet - Oral, Oral, Kit
Osteoarthritis (OA)
, 20.0 mg, 10.0 mg
Rectal, Suppository, Suppository - Rectal, Capsule, Capsule - Oral, Tablet, , Tablet - Oral, Oral, Kit
Rheumatoid Arthritis
, 20.0 mg, 10.0 mg
Rectal, Suppository, Suppository - Rectal, Capsule, Capsule - Oral, Tablet, , Tablet - Oral, Oral, Kit
Warnings
Feldene has two restrictions; it must not be conjoined with the conditions specified in the subsequent table.Feldene ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Coronary Artery Bypass Grafting
Do Not Combine
Common Feldene Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The metabolism of Amiodarone can be decreased when combined with Piroxicam.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Piroxicam.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Piroxicam.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Piroxicam.
Fluorouracil
Major
The metabolism of Fluorouracil can be decreased when combined with Piroxicam.
Feldene Toxicity & Overdose RiskSymptoms of an overdose on this drug include drowsiness, nausea, stomach ache, and vomiting.
Feldene Novel Uses: Which Conditions Have a Clinical Trial Featuring Feldene?
78 active clinical trials are in progress to assess the potential of Feldene to mitigate Osteoarthritis (OA), Rheumatoid Arthritis and Ankylosing Spondylitis.Condition
Clinical Trials
Trial Phases
Osteoarthritis (OA)
0 Actively Recruiting
Ankylosing Spondylitis
2 Actively Recruiting
Phase 3, Not Applicable
Rheumatoid Arthritis
62 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Feldene Reviews: What are patients saying about Feldene?
5Patient Review
10/16/2017 This drug is excellent because it helps me move around without a lot of pain. However, if I miss a few doses, I feel like I've been hit by a train and have to stay in bed.
5Patient Review
6/18/2013 This medication removed all of my pain and stiffness from arthritis. It was perfect for me.
5Patient Review
2/22/2011 Though it only provides temporary relief, this treatment is still effective. I also experienced slight blurry vision while on the medication; however, this could be because I was taking it at night instead of in the morning as directed.
5Patient Review
8/25/20104.7Patient Review
10/28/2015 I believe that this medication will work for most people who take it; however, it's important to be aware that NSAIDs can damage your stomach lining. I would recommend asking your doctor for a prescription for Cytotec to protect your stomach while taking this medication. I've been taking this combination for years without any serious problems.
4Patient Review
10/25/2010 This medication really helps me to get through day-to-day activities.
3.3Patient Review
5/2/2013 I've been on piroxicam for a while and had to stop because I started getting bruises from bumps. Recently, the pain became too much so I decided to start taking it again at night. So far, no issues with bruising!
3Patient Review
7/23/2012 I had a really terrible experience with this drug. I got a rash that felt like needles, and it was so itchy. The sun made it worse, too. I had to go on emergency steroids for a week just to recover.
3Patient Review
1/17/2011 The first dose caused major stomach pain which required an acid reducer, but the pain persisted. Now I suffer from chronic stomach pain and frequently need treatment for acid reflux like symptoms.
2Patient Review
5/17/2014 I found this medication effective in reducing my joint pain; however, I developed a rash and had to discontinue use.
1.7Patient Review
12/29/2012 Unfortunately, I had an allergic reaction in the form of hives. Had to go to the hospital and get a shot of steroids.
1Patient Review
12/7/2010 While it's great that this medication lessens pain, sometimes to the point of complete disappearance, it does come with some pretty severe side effects. Stomach problems are common, as is intense itching.
Patient Q&A Section about feldene
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Feldene the same as ibuprofen?
"Both piroxicam and ibuprofen are NSAIDs that relieve pain and reduce inflammation. Piroxicam is only available with a prescription, but ibuprofen is available without a prescription (over-the-counter)."
Answered by AI
What is Feldene tablets used for?
"The drug Feldene is intended to provide relief from the symptoms of osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis. However, because of potential safety concerns (as described in sections 4.2, 4.3, and 4.4 of the accompanying literature), Feldene should not be the first choice of medication if an anti-inflammatory drug is needed."
Answered by AI
Is Feldene still on the market?
"The group then characterized the drug as an "imminent hazard to the public health" and urged the FDA to ban prescriptions of Feldene to people aged 60 and older, who are most at risk for severe side effects. However, after conducting a review, the FDA decided that Feldene should remain on the market."
Answered by AI
What are the side effects of Feldene?
"You may experience abnormal liver function tests, urination problems, upset stomach, heartburn, loss of appetite, stomach pain, nausea, vomiting, gas, diarrhea, constipation, dizziness, headache, itching, or rash. You may also experience ringing in your ears."
Answered by AI