Feldene

Rheumatoid Arthritis, Ankylosing Spondylitis, Osteoarthritis
Treatment
5 FDA approvals
20 Active Studies for Feldene

What is Feldene

PiroxicamThe Generic name of this drug
Treatment SummaryIbuprofen is a type of medication that reduces inflammation and pain. It is commonly used to treat conditions such as rheumatoid arthritis, osteoarthritis, and other musculoskeletal disorders. Ibuprofen can also be used to treat menstrual cramps and post-surgery pain. It has a long-lasting effect, so it only needs to be taken once a day.
Piroxicamis the brand name
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Feldene Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Piroxicam
Piroxicam
1993
85

Approved as Treatment by the FDA

Piroxicam, also known as Piroxicam, is approved by the FDA for 5 uses such as Osteoarthritis (OA) and Ankylosing Spondylitis (AS) .
Osteoarthritis (OA)
Ankylosing Spondylitis (AS)
Osteoarthritis
Ankylosing Spondylitis
Rheumatoid Arthritis

Effectiveness

How Feldene Affects PatientsPiroxicam is a type of medicine called a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the hormones that cause pain and inflammation in the body. It is used to help relieve pain, swelling and stiffness caused by rheumatoid arthritis and osteoarthritis.
How Feldene works in the bodyPiroxicam reduces inflammation by blocking an enzyme called Cox-1. This enzyme is responsible for producing prostaglandins, which are chemicals that cause inflammation. Piroxicam also prevents white blood cells from entering sites of inflammation and stops platelets from making a chemical that causes clots.

When to interrupt dosage

The suggested dosage of Feldene is contingent upon the diagnosed condition, including Osteoarthritis (OA), Rheumatoid Arthritis and Ankylosing Spondylitis. The amount of dosage varies as per the technique of delivery (e.g. Rectal or Suppository) portrayed in the table beneath.
Condition
Dosage
Administration
Rheumatoid Arthritis
10.0 mg, 20.0 mg,
, Oral, Capsule, Capsule - Oral, Kit, Suppository, Rectal, Suppository - Rectal, Tablet, Tablet - Oral
Ankylosing Spondylitis
10.0 mg, 20.0 mg,
, Oral, Capsule, Capsule - Oral, Kit, Suppository, Rectal, Suppository - Rectal, Tablet, Tablet - Oral
Osteoarthritis
10.0 mg, 20.0 mg,
, Oral, Capsule, Capsule - Oral, Kit, Suppository, Rectal, Suppository - Rectal, Tablet, Tablet - Oral

Warnings

Feldene has two restrictions; it must not be conjoined with the conditions specified in the subsequent table.Feldene Contraindications
Condition
Risk Level
Notes
Coronary Artery Bypass Grafting
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Feldene.
Common Feldene Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The metabolism of Amiodarone can be decreased when combined with Piroxicam.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Piroxicam.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Piroxicam.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Piroxicam.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Piroxicam.
Feldene Toxicity & Overdose RiskSymptoms of an overdose on this drug include drowsiness, nausea, stomach ache, and vomiting.
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Feldene Novel Uses: Which Conditions Have a Clinical Trial Featuring Feldene?

78 active clinical trials are in progress to assess the potential of Feldene to mitigate Osteoarthritis (OA), Rheumatoid Arthritis and Ankylosing Spondylitis.
Condition
Clinical Trials
Trial Phases
Osteoarthritis
0 Actively Recruiting
Rheumatoid Arthritis
54 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Ankylosing Spondylitis
3 Actively Recruiting
Phase 3, Not Applicable

Feldene Reviews: What are patients saying about Feldene?

5Patient Review
10/16/2017
Feldene for Joint Damage causing Pain and Loss of Function
This drug is excellent because it helps me move around without a lot of pain. However, if I miss a few doses, I feel like I've been hit by a train and have to stay in bed.
5Patient Review
6/18/2013
Feldene for Joint Damage causing Pain and Loss of Function
This medication removed all of my pain and stiffness from arthritis. It was perfect for me.
5Patient Review
2/22/2011
Feldene for Joint Damage causing Pain and Loss of Function
Though it only provides temporary relief, this treatment is still effective. I also experienced slight blurry vision while on the medication; however, this could be because I was taking it at night instead of in the morning as directed.
5Patient Review
8/25/2010
Feldene for Joint Damage causing Pain and Loss of Function
4.7Patient Review
10/28/2015
Feldene for Joint Damage causing Pain and Loss of Function
I believe that this medication will work for most people who take it; however, it's important to be aware that NSAIDs can damage your stomach lining. I would recommend asking your doctor for a prescription for Cytotec to protect your stomach while taking this medication. I've been taking this combination for years without any serious problems.
View All Reviews
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Patient Q&A Section about feldene

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Feldene the same as ibuprofen?

"Both piroxicam and ibuprofen are NSAIDs that relieve pain and reduce inflammation. Piroxicam is only available with a prescription, but ibuprofen is available without a prescription (over-the-counter)."

Answered by AI

What is Feldene tablets used for?

"The drug Feldene is intended to provide relief from the symptoms of osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis. However, because of potential safety concerns (as described in sections 4.2, 4.3, and 4.4 of the accompanying literature), Feldene should not be the first choice of medication if an anti-inflammatory drug is needed."

Answered by AI

Is Feldene still on the market?

"The group then characterized the drug as an "imminent hazard to the public health" and urged the FDA to ban prescriptions of Feldene to people aged 60 and older, who are most at risk for severe side effects. However, after conducting a review, the FDA decided that Feldene should remain on the market."

Answered by AI

What are the side effects of Feldene?

"You may experience abnormal liver function tests, urination problems, upset stomach, heartburn, loss of appetite, stomach pain, nausea, vomiting, gas, diarrhea, constipation, dizziness, headache, itching, or rash. You may also experience ringing in your ears."

Answered by AI

Clinical Trials for Feldene

Have you considered Feldene clinical trials? We made a collection of clinical trials featuring Feldene, we think they might fit your search criteria.
Have you considered Feldene clinical trials? We made a collection of clinical trials featuring Feldene, we think they might fit your search criteria.
Have you considered Feldene clinical trials? We made a collection of clinical trials featuring Feldene, we think they might fit your search criteria.