Your session is about to expire
← Back to Search
Pembrolizumab for Lymphoma
Study Summary
This trial is testing whether the drug pembrolizumab can help treat people with Hodgkin lymphoma or primary mediastinal large B-cell lymphoma.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2024 Phase 2 trial • 57 Patients • NCT03004183Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- You have a severe allergic reaction (Grade 3 or higher) to pembrolizumab or any of its ingredients.I have received CAR-T cell therapy before.I have had a serious heart condition or stroke in the last 6 months.I had another cancer but have been cancer-free for 2 years, except for certain skin, bladder, cervical, or in situ cancers.I have been treated with specific immune therapy drugs before.My cancer can be measured on scans and has a large enough lesion that hasn't been treated with radiation.I haven't had monoclonal antibody treatment in the last 4 weeks or have recovered from its side effects.I am using effective birth control or have been abstinent, and will continue for 120 days after the study ends.I am on high-dose steroids (more than 10 mg of prednisone or equivalent) but started less than 3 days ago, except for daily replacement therapy.My lymphoma has spread to my brain or spinal cord.I haven't needed systemic treatment for an autoimmune disease in the last 2 years.I am currently being treated for an infection.I have not received a live vaccine in the last 30 days.I have or had lung inflammation that needed steroids.My cancer returned or didn't respond well after my stem cell transplant.I can provide a recent or older lymph node biopsy for testing.I am not pregnant or breastfeeding.I've had 2+ treatments for my condition and didn't respond well to the last one, including a treatment with rituximab.My Hodgkin's lymphoma returned after my last treatment.I've had at least one treatment for Hodgkin lymphoma and it didn't work or the cancer came back.I have a history of Hepatitis B or active Hepatitis C.My PMBCL cancer has returned or is not responding to treatment.My diagnosis is cHL or PMBCL, as confirmed by a lab test.My organs are working well.I haven't had radiotherapy in the last 2 weeks and have no lung damage from past treatments.I have an immune system disorder or have been on high-dose steroids or other immune-weakening medicines recently.I haven't had cancer treatment or major surgery in the last 4 weeks.I am fully active or restricted in physically strenuous activity but can do light work.I have had a solid organ transplant or a bone marrow transplant in the last 5 years.I have fluid around my heart or in my lungs.My Hodgkin lymphoma has returned or is not responding to treatment.
- Group 1: Arm 1
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Has Pembrolizumab received regulatory approval from the FDA?
"Pembrolizumab is still being tested for efficacy in Phase 2 trials, however there is some data supporting its safety--so it received a score of 2."
What is the purpose of this clinical trial?
"The primary focus of this long-term trial is to observe the Objective Response Rate (ORR) and Percentage of Participants with Complete Response (CR) or Partial Response (PR) over the course of approximately 40 months. Additionally, researchers will be looking at secondary outcomes such as Number of Participants with Adverse Events (AEs), Duration of Response (DOR), and Number of Participants Who Discontinued Study Treatment Due to AEs."
Does this clinical trial have any open slots for new patients?
"This trial is not presently recruiting patients, as per the information on clinicaltrials.gov. The clinical trial was initially posted on 6/7/2021 and was most recently edited on 10/20/2022. Although this particular trial is not looking for patients at this time, there are 2791 other trials that are actively searching for participants."
Are there other ongoing studies that include Pembrolizumab?
"Pembrolizumab is being trialed in 1000 different ongoing clinical studies. 122 of those are large-scale Phase 3 trials. Although many of the investigations are based out of Houston, Texas, there are 36034 total locations running Pembrolizumab studies."
How many test subjects are participating in this clinical trial?
"Unfortunately, this trial is no longer recruiting patients. The listing was created on June 7th 2021 and last updated on October 20th 2022. There are other studies you may be eligible for - 1791 trials for lymphoma, b-cell and 1000 for Pembrolizumab are currently enrolling participants."
What is Pembrolizumab's most common purpose?
"Pembrolizumab is a medication that oncologists use to treat malignant neoplasms. However, it can also be used for the treatment of other conditions such as unresectable melanoma and microsatellite instability high."
Share this study with friends
Copy Link
Messenger