Your session is about to expire
← Back to Search
Etrasimod for Ulcerative Colitis (ELEVATE UC OLE Trial)
ELEVATE UC OLE Trial Summary
This trial will assess the safety and efficacy of etrasimod in people with moderate-to-severe UC who have previously received treatment in a double-blind study.
ELEVATE UC OLE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2022 Phase 3 trial • 42 Patients • NCT04706793ELEVATE UC OLE Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- People who were previously enrolled in the study called APD334-302 must have finished their visit at Week 12.I was in a previous study and either my UC didn't improve by Week 12 or I completed Week 52.
- Group 1: Etrasimod 2 mg
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this study only for patients who are 35 years or older?
"Patients that meet the requirements for this study must be between 16 and 80 years old. There are 72 clinical trials for people under 18 and 369 for patients over 65."
What makes this research project unique compared to others?
"There are currently 7 active clinical trials for Etrasimod in 368 cities and 50 countries. The first trial was conducted in 2019 by Arena Pharmaceuticals. 912 participants were involved and the study completed its Phase 3 drug approval stage. Since then, 6 more trials have been carried out."
When will Etrasimod be cleared for public use by the FDA?
"Etrasimod has been rated a 3 for safety by our team at Power. This is because there is some data supporting efficacy and multiple rounds of data supporting safety, as this is a Phase 3 trial."
In how many different places is this trial being conducted?
"Right now, there are 44 different enrolling sites for this study. While some locations are in Ogden, Orange and La Jolla, other enrolment centres are more widespread to allow closer proximity for potential participants. If you do decide to take part in this research project, try to choose the location that is closest to reduce travel burden."
Who would be an eligible candidate for this research?
"Eligible patients for this study must have a diagnosis of colitis, be between 16-80 years old, and meet one the following criteria: -Have completed the Week 12 visit in Study APD334-301 (NCT03945188) or APD334-210 (NCT04607837), with an assessment of active UC that has not improved or has worsened from baseline. -OR have completed the Week 52 visit in APD334-302 (NCT03996369)."
How many individuals are taking part in this research project?
"912 patients that pass the screening process are necessary to run this study smoothly. Arena Pharmaceuticals, the trial's sponsor, will be managing different research sites; two examples include Care Access Research LLC in Ogden, Utah and University of California, Irvine in Orange, California."
Are there precedents for this Etrasimod clinical trial?
"Etrasimod was first studied in 2019 at Fakultni nemocnice u svate Anny v Brne. There have been 6 completed trials since then, with 7 more active clinical trials as of now. Many of these are based in Ogden, Utah."
Are patients being actively sought for this experiment?
"That is correct, the online information portal clinicaltrials.gov has this trial listed as currently seeking participants. The 912 patients will be drawn from 44 different hospitals, clinics, and medical research institutions."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Share this study with friends
Copy Link
Messenger