What is Evoclin
ClindamycinThe Generic name of this drug
Treatment SummaryClindamycin is an antibiotic used to treat a range of bacterial infections. It can also be used topically to treat acne. Clindamycin has a limited spectrum of activity, meaning it only works against certain types of bacteria. Additionally, it holds some activity against protozoans, and is sometimes used off-label to treat toxoplasmosis, malaria, and babesiosis. Clindamycin is a semi-synthetic version of lincomycin, a naturally occurring lincosamide antibiotic, and is considered to be more effective than its predecessor. The name lincomycin comes from the city
Cleocin Hydrochlorideis the brand name
Evoclin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cleocin Hydrochloride
Clindamycin
1970
501
Effectiveness
How Evoclin Affects PatientsClindamycin works by preventing bacteria from creating proteins, which stops them from multiplying. It needs to be taken every six hours to keep the antibiotic effective. Clindamycin can cause a type of diarrhea called Clostridium difficile associated diarrhea (CDAD) which can range from mild diarrhea to life-threatening colitis. This is why clindamycin should only be used for serious infections that cannot be treated with less harmful antibiotics. Clindamycin is effective against many types of bacteria, including both aerobes and anaerobes, however resistance to the drug may develop over time. It is recommended
How Evoclin works in the bodyClindamycin works by blocking bacteria from making proteins. It does this by binding to a part of the bacterial ribosome, which is necessary for protein formation. Clindamycin also has an effect on Propionibacterium acnes, a bacteria linked to acne. It's not clear how it works against acne, but this is likely to be one of the ways.
When to interrupt dosage
The prescribed dosage of Evoclin is contingent upon the diagnosed condition, such as viridans group streptococci, Vaginal Infections and Surgical Intervention. The amount of dosage is contingent upon the delivery approach (e.g. Cream - Vaginal or Suspension - Topical) listed in the table below.Condition
Dosage
Administration
Heart Valve Prosthesis
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Vaginal Infections
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Peritonitis caused by Anaerobic Bacterial Infection
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Surgically constructed systemic-pulmonary shunt
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Endometritis caused by Anaerobic Bacterial Infection
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Bacteria, Anaerobic
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Lung Abscess caused by Anaerobic Bacterial Infection
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Mitral Valve Prolapse
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Bacterial Vaginosis
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Vaginal Candidiasis
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Bacteria, Anaerobic
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Pregnancy
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Respiratory Tract Infections (RTI) caused by susceptible streptococci
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Bacteria, Anaerobic
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Respiratory Tract Infections (RTI) caused by susceptible pneumococci
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Bacteria, Anaerobic
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Pneumocystis Jirovecii Pneumonia
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Hypertrophic Cardiomyopathy
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Acquired valvular dysfunction
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Toxoplasmosis
150.0 mg, 150.0 mg/mL, 100.0 mg, 300.0 mg, 0.01 mg/mg, , 10.0 mg, 18.0 mg/mL, 12.0 mg/mL, 30.0 mg/mL, 1.2 %, 0.02 mg/mg, 60.0 mg/mL, 0.012 mg/mg, 75.0 mg/mL, 6.0 mg/mL, 90.0 mg/mL, 1.0 %, 10.0 mg/mL, 100.0 mg/mL, 0.1 mg/mg, 0.007 mg/mg, 75.0 mg, 11.9 mg/mL, 5.0 mg/mg, 0.01 mg/mL
Cream - Vaginal, Suspension - Topical, Solution - Topical, , Capsule - Oral, Solution - Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Gel - Topical, Kit - Intramuscular; Intravenous, Solution, Gel; Kit; Powder, for solution - Topical, Kit, Injection, Topical, Cream - Topical, Aerosol, foam - Topical, Oral, Aerosol, foam, Kit - Topical, Granule, for solution, Cream, Capsule, gelatin coated, Injection, solution - Intravenous, Vaginal, Swab - Topical, Gel, Powder, for solution - Oral, Injection, solution, Suspension, Capsule, Swab, Capsule, gelatin coated - Oral, Injection - Intravenous, Intravenous, Infiltration; Intramuscular; Intravenous, Solution - Intravenous, Gel - Vaginal, Injection, solution, concentrate - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Granule, for solution - Oral, Lotion, Injection, solution, concentrate - Intramuscular; Intravenous, Suppository - Vaginal, Lotion - Topical, Suppository, Injection - Intramuscular; Intravenous, Liquid, Kit - Infiltration; Intramuscular; Intravenous, Gel; Kit; Powder, for solution, Powder, for solution, Injection, solution, concentrate, Solution - Oral
Warnings
Evoclin ContraindicationsCondition
Risk Level
Notes
Crohn Disease
Do Not Combine
Ulcerative Colitis
Do Not Combine
History of Antibiotics Associated Colitis
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Clindamycin may interact with Toxoplasma Infections
Common Evoclin Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Clindamycin.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Clindamycin.
Bromocriptine
Major
The serum concentration of Bromocriptine can be increased when it is combined with Clindamycin.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Clindamycin.
Cabergoline
Major
The serum concentration of Cabergoline can be increased when it is combined with Clindamycin.
Evoclin Toxicity & Overdose RiskThe toxic dose of clindamycin in mice and rats has been recorded as 2540 mg/kg and 2190 mg/kg respectively. No cases of overdose have been reported, but symptoms could include abdominal pain, nausea, vomiting, and diarrhea. One 3-year-old child was given 100 mg/kg daily for 5 days and only experienced mild abdominal pain and diarrhea. Activated charcoal may be used to remove unabsorbed drug, but hemodialysis and peritoneal dialysis will not be effective. General supportive measures are recommended if someone takes too much clindamycin.
Evoclin Novel Uses: Which Conditions Have a Clinical Trial Featuring Evoclin?
Presently, 73 active clinical trials are underway to assess the potential of Evoclin in alleviating Bacterial Endocarditis, Acne and Pneumocystis Jirovecii Pneumonia.Condition
Clinical Trials
Trial Phases
Bacterial Endocarditis
0 Actively Recruiting
Bacterial Endocarditis
0 Actively Recruiting
viridans group streptococci
0 Actively Recruiting
Respiratory Tract Infections
0 Actively Recruiting
Bacterial Vaginosis
5 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1
Bacteria, Anaerobic
0 Actively Recruiting
penicillins
3 Actively Recruiting
Not Applicable, Phase 4
Acquired Immunodeficiency Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Phase 1, Not Applicable
Mitral Valve Prolapse
0 Actively Recruiting
Bacteria, Anaerobic
0 Actively Recruiting
Bone and Bones
0 Actively Recruiting
Surgical Intervention
0 Actively Recruiting
Vaginal Mycosis
0 Actively Recruiting
Bacteria, Anaerobic
0 Actively Recruiting
Pneumocystis Jirovecii Pneumonia
1 Actively Recruiting
Phase 3
Bacteria, Anaerobic
0 Actively Recruiting
Respiratory Tract Infections (RTI) caused by susceptible pneumococci
0 Actively Recruiting
Peritonitis caused by Anaerobic Bacterial Infection
0 Actively Recruiting
Pelvic cellulitis caused by Anaerobic Bacterial Infection
0 Actively Recruiting
Heart Valve Prosthesis
0 Actively Recruiting
Evoclin Reviews: What are patients saying about Evoclin?
5Patient Review
8/29/2009 Used this in conjunction with Proactiv Cleanser and it was very effective at minimizing the appearance of large pores.
5Patient Review
8/29/2009 This stuff works wonders on acne and blackheads. You'll see a difference in no time flat!
5Patient Review
5/28/2009 I've been using this product for acne treatment twice daily for almost three weeks now, and not only has it cleared up my skin, but the pores by my nose and chin that have always been larger have gotten a lot smaller. I'm very happy with this product!
5Patient Review
4/3/2008 I've tried a lot of different things to get rid of my acne, but none of them worked as well as Evoclin. I'm really happy with the results.
4.7Patient Review
6/11/2009 I used to love this medication because it was so easy and effective, but I think it's stopped working for me.
4.3Patient Review
2/10/2010 I'm 28 and I have chest acne. I'm on week 2 and I see a significant reduction in my acne. My skin is not irritated or dry, which is amazing.
3.3Patient Review
6/3/2008 I'm a teenager with acne. I sought treatment for it, and while this did eventually help dry out my skin, it wasn't as effective as other treatments I've tried since then.
1.7Patient Review
3/24/2011 I didn't see any reduction in the number of sores on my scalp.
Patient Q&A Section about evoclin
What does clindamycin do for acne?
"Topical clindamycin is a medication used to treat acne. Clindamycin is an antibiotic that works by stopping the growth of bacteria that cause acne." - Anonymous Online Contributor
Unverified Answer
Who makes Evoclin?
"Suspected adverse reactions should be reported to Stiefel Laboratories, Inc. at 1-888-784-3335 (1-888-STIEFEL) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch." - Anonymous Online Contributor
Unverified Answer
What does clindamycin gel do?
"Topical clindamycin is a medication used to treat acne. It is usually applied to the skin once or twice a day. It may be used alone or in combination with other acne treatments. Topical clindamycin may also be used to treat other conditions as prescribed by a doctor. Clindamycin requires a doctor's prescription." - Anonymous Online Contributor
Unverified Answer
What is evoclin used for?
"This acne medication helps to reduce the number of pimples by using the antibiotic clindamycin to kill bacteria." - Anonymous Online Contributor
Unverified Answer