Evekeo

Narcolepsy, Depression, Attention Deficit Hyperactivity Disorder + 1 more
Treatment
2 FDA approvals
20 Active Studies for Evekeo

What is Evekeo

AmphetamineThe Generic name of this drug
Treatment SummaryAmphetamine is a type of drug that has been around for over 100 years. It was once used to treat a variety of conditions, but now it is only used in limited cases. Amphetamine has the chemical formula alpha-methylphenethylamine and was originally developed in 1910 and synthesized by 1927. It was used to reduce drug-induced anesthesia, promote wakefulness, and cause arousal and insomnia. During World War II, it was used to help keep soldiers awake. However, after the war ended, excess supplies of amphetamine ended up in the black market, leading to its misuse and illicit abuse.
Adderallis the brand name
image of different drug pills on a surface
Evekeo Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Adderall
Amphetamine
1996
507

Approved as Treatment by the FDA

Amphetamine, also known as Adderall, is approved by the FDA for 2 uses which include Attention Deficit Hyperactivity Disorder and Narcolepsy .
Attention Deficit Hyperactivity Disorder
Used to treat Attention Deficit Hyperactivity Disorder (ADHD) in combination with Dextroamphetamine
Narcolepsy

Effectiveness

How Evekeo Affects PatientsAmphetamine increases the amount of two important brain chemicals, noradrenaline and dopamine. It has been used to improve intelligence test scores, and has been shown to help people with ADHD improve their school performance, behavior, and demeanor. It is usually used in a 3:1 ratio of two forms of the drug. While it is sometimes used to treat depression and anxiety, amphetamine use can also lead to a paranoid state and should not be misused.
How Evekeo works in the bodyAmphetamine works by mimicking the structure and action of neurotransmitters. It competes with the neurotransmitters to be taken up by nerve terminals, and is then stored in vesicles. It is then released into the synapse where it blocks the reuptake of dopamine, noradrenaline, and serotonin. Lastly, it inhibits an enzyme responsible for breaking down excess neurotransmitters.

When to interrupt dosage

The suggested dose of Evekeo relies upon the diagnosed affliction, including Disease, Chronic Pain and Attention Deficit Hyperactivity Disorder. The measure of dosage can be found in the indicated table, based on the technique of delivery (e.g. Oral or Tablet - Oral).
Condition
Dosage
Administration
Narcolepsy
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral
Depression
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral
Chronic Pain
, 5.0 mg, 10.0 mg, 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, 18.8 mg, 2.5 mg/mL, 3.125 mg, 9.375 mg, 6.25 mg, 1.875 mg, 2.5 mg, 7.5 mg, 1.25 mg, 3.75 mg, 15.0 mg, 1.25 mg/mL, 18.75 mg, 25.0 mg, 7.26 mg, 12.11 mg, 2.42 mg, 9.69 mg, 14.53 mg, 4.84 mg, 20.0 mg, 60.0 mg, 40.0 mg, 30.0 mg
Tablet - Oral, , Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Suspension, extended release - Oral, Suspension, extended release, Capsule - Oral, Capsule, Tablet, extended release, Tablet, extended release - Oral

Warnings

Evekeo Contraindications
Condition
Risk Level
Notes
Agitation
Do Not Combine
advanced arteriosclerosis
Do Not Combine
Drug abuse
Do Not Combine
Hyperthyroidism
Do Not Combine
Hypertensive disease
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Amphetamine may interact with Pulse Frequency
There are 20 known major drug interactions with Evekeo.
Common Evekeo Drug Interactions
Drug Name
Risk Level
Description
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Amphetamine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Amphetamine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Amphetamine.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Amphetamine.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Amphetamine.
Evekeo Toxicity & Overdose RiskThe mean lethal dose of amphetamine is 6.4 mg/l. Symptoms of an overdose include high body temperature, decreased breathing, seizures, acidity of the blood, kidney failure, liver damage, and loss of consciousness. Other effects may include agitation, aggressive behavior, headache, hallucinations, irregular heartbeat, heart muscle damage, abdominal pain, vomiting, diarrhea, cramps, lack of appetite, and bleeding in the digestive tract. In animal studies, amphetamine has not been linked to cancer, genetic mutation, or fertility problems.
image of a doctor in a lab doing drug, clinical research

Evekeo Novel Uses: Which Conditions Have a Clinical Trial Featuring Evekeo?

710 active experiments are being conducted to investigate the potential of Evekeo to combat Depression, Disease and Narcolepsy.
Condition
Clinical Trials
Trial Phases
Narcolepsy
9 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4, Phase 1
Attention Deficit Hyperactivity Disorder
75 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Chronic Pain
32 Actively Recruiting
Phase 2, Not Applicable, Phase 3
Depression
693 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1, Early Phase 1, Phase 4

Evekeo Reviews: What are patients saying about Evekeo?

5Patient Review
6/24/2015
Evekeo for Attention Deficit Disorder with Hyperactivity
I've tried so many other treatments and they either don't work or I feel awful on them. This one works quickly and lasts about 7 hours for me. I've been on it for two weeks and haven't had any side effects really. I also received a free trial and I did not have to pay anything for a 60 tablet supply. My doc also gave me a copay card to use after that will really keep the cost down. Safe to say I'll be sticking with Evekeo!
5Patient Review
8/3/2015
Evekeo for Attention Deficit Disorder with Hyperactivity
This is my first time taking medication for ADHD, and I think it's helping. I started with a low dose of 5mg twice a day, and increased it to 10mg after a week. I felt some side effects at the lower dose, but they were manageable. So far so good, and I plan on continuing the treatment for now.
5Patient Review
10/2/2015
Evekeo for Attention Deficit Disorder with Hyperactivity
I found this treatment to be much better than generic adderall. It lasts longer and helped me focus more. The free trial is also a nice bonus so you can test it out before committing to it.
5Patient Review
5/17/2016
Evekeo for Attention Deficit Disorder with Hyperactivity
After trying other drugs, my doctor recommended this one. It helps me focus without any terrible side effects, which I'm grateful for.
5Patient Review
6/23/2018
Evekeo for Weight Loss Management for an Obese Person
In just four months, I've dropped 40 pounds. Evekeo makes it much easier to diet and exercise by suppressing my appetite and giving me energy boosts. It's been wonderful for me; the only downside is that sometimes my heart races, even though my blood pressure seems fine.
5Patient Review
4/20/2018
Evekeo for Attention Deficit Disorder with Hyperactivity
I appreciate the fact that I was able to get a free trial from my doctor. My son's ADHD is much better managed now and he's doing great in school again. The flexible dosing is really helpful, and it only costs me $15 per month through our local pharmacy copay program.
5Patient Review
5/4/2018
Evekeo for Attention Deficit Disorder with Hyperactivity
I wasn't able to focus before taking this medication, and it was really disrupting my life. Evekeo has been a lifesaver for me, 10mg is the perfect amount to help me get through my day without feeling jittery or out of control.
4.3Patient Review
12/8/2015
Evekeo for Attention Deficit Disorder with Hyperactivity
I've tried four different medications for my ADD and this one by far is the best. I just wish they had higher strengths available; 15mg twice daily works well for me, but I have to break the tablet in half which is annoying. There are no side effects that I've noticed and it really helps with my attention deficit disorder.
4.3Patient Review
8/31/2015
Evekeo for Attention Deficit Disorder with Hyperactivity
I've been using this for two weeks and it's definitely better than Adderall. The only downside is that I turn into a bit of a jerk at the end of the day, but smoking some weed takes care of that.
3Patient Review
5/12/2016
Evekeo for Attention Deficit Disorder with Hyperactivity
Recently switched to Evekeo, but it was difficult to find a pharmacy that had it in stock. Additionally, my insurance didn't cover it. The coupon from the doctor helped offset some of the cost, but I think I'm going to switch back to my old medication (Adderall Tablet).
1.3Patient Review
6/25/2018
Evekeo for Attention Deficit Disorder with Hyperactivity
I found this treatment to be ineffective and actually quite counterproductive. It made me more sleepy and irritable, rather than helping my ADHD symptoms.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about evekeo

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic for Evekeo?

"Evekeo is a medication used to treat attention deficit hyperactivity disorder (ADHD). It is a short-acting stimulant that is taken orally. It is available in tablet and capsule form."

Answered by AI

How does Evekeo make you feel?

"It's common for people to abuse Evekeo because it affects dopamine levels in the brain and can create a feeling of euphoria. When people abuse large doses of Evekeo, this feeling is even more intense."

Answered by AI

What is the difference between Adderall and Evekeo?

"Evekeo is an ADHD stimulant medication that was approved by the FDA in 2014. It is an amphetamine sulfate that is similar to Adderall, but it has a different composition. Adderall is 75 percent dextroamphetamine and 25 percent levoamphetamine, whereas Evekeo is an even 50 percent of each."

Answered by AI

What is Evekeo used for?

"Amphetamine is a medication used to treat attention deficit hyperactivity disorder (ADHD). It works by changing the amounts of certain natural substances in the brain. Amphetamine belongs to a class of drugs known as stimulants."

Answered by AI

Clinical Trials for Evekeo

Have you considered Evekeo clinical trials? We made a collection of clinical trials featuring Evekeo, we think they might fit your search criteria.
Have you considered Evekeo clinical trials? We made a collection of clinical trials featuring Evekeo, we think they might fit your search criteria.
Have you considered Evekeo clinical trials? We made a collection of clinical trials featuring Evekeo, we think they might fit your search criteria.