This trial studies a drug to treat heart failure and pulmonary hypertension by reducing pulmonary vascular resistance.
- Pulmonary Hypertension
- Heart Failure
1 Primary · 25 Secondary · Reporting Duration: On Day 15, Day 29, Day 85, Day 127, Day 169, and Day 211
4 Treatment Groups
AZD3427 Dose A
1 of 4
AZD3427 Dose B
1 of 4
AZD3427 Dose C
1 of 4
1 of 4
220 Total Participants · 4 Treatment Groups
Primary Treatment: AZD3427 Dose A · Has Placebo Group · Phase 2
Who is running the clinical trial?
Age 18 - 130 · All Participants · 6 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
|Did not meet criteria||100.0%|
Why did patients apply to this trial?
- "Trying to help and need money"
How many prior treatments have patients received?
Frequently Asked Questions
Does this trial include participants of a younger age demographic?
"The requirements for admission to this trial are patients aged between 18 and 130 years old. There exists 79 studies catering exclusively toward those younger than 18, while 1363 trials address the needs of individuals over 65." - Anonymous Online Contributor
What is the current enrolment for this clinical research?
"Confirmed. Various details on clinicaltrials.gov suggest that this medical study, initially published on April 24th 2023, is actively looking for participants to enrol in the trial. Across 45 different locations 220 patients are being sought." - Anonymous Online Contributor
Has the Food and Drug Administration sanctioned the use of AZD3427 Dose A?
"While the efficacy of AZD3427 Dose A is yet to be established, its safety has been investigated and earned a score of 2." - Anonymous Online Contributor
Are there any open enrollment opportunities for this experiment?
"Affirmative. Sources on clinicaltrials.gov demonstrate that this trial, which first launched on April 24th 2023, is still recruiting participants. 220 volunteers are being sought from 45 different sites for the study." - Anonymous Online Contributor
How many settings are conducting this research project?
"45 sites are currently participating in this medical trial. These locations, which span from New Haven to Saint Louis, have been carefully chosen so that participants can easily access the nearest one and reduce travel requirements if they choose to enroll." - Anonymous Online Contributor
What is the participant criteria for this research endeavor?
"This clinical trial is in search of two hundred and twenty individuals aged between 18 to 130 who suffer from pulmonary hypertension. Potential participants must fulfil the following requirements: be of legal age, have a pre-existing heart failure diagnosis (NYHA FC II - IV), possess combined echocardiographic readings that are indicative of intermediate or high probability for PH (ESC/ERS 2022 Guidelines); exhibit an elevated PAWP (>15 mmHg) and mPAP (>20mmHG); have a minimum body weight of 50kg; provide valid consenting documentation." - Anonymous Online Contributor