What is Eskalith Cr
Lithium carbonateThe Generic name of this drug
Treatment SummaryLithium has a long history of use as a treatment for episodes of mania, though it is not yet clear how it works to treat these episodes. It is important to closely monitor the amount of lithium taken, as there is a small range between the therapeutic and harmful levels of the drug.
Eskalithis the brand name
Eskalith Cr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Eskalith
Lithium carbonate
1970
174
Effectiveness
How Eskalith Cr Affects PatientsThe exact way that lithium works is not completely understood. It may work by blocking certain enzymes or altering how our body responds to glutamate, a type of chemical messenger.
How Eskalith Cr works in the bodyThe exact mechanism of how lithium works is not known. The most likely explanation is that it affects three different parts of the cell. First, lithium prevents an enzyme from breaking down inositol, a molecule found in the cell. Second, it blocks another enzyme from working, although the effects of this are not fully understood. Third, it helps regulate a protein called GSK-3, which controls other proteins through a process called phosphorylation. It may also prevent GSK-3 from working by blocking the magnesium ion in its active site.
When to interrupt dosage
The prescribed dosage of Eskalith Cr is determined by the diagnosed condition. The measure of dosage fluctuates, based on the method of delivery (e.g. Oral or Tablet, extended release - Oral) noted in the table underneath.Condition
Dosage
Administration
Behcet Syndrome
150.0 mg, 450.0 mg, 300.0 mg, 8.0 meq/mL, , 600.0 mg, 250.0 mg, 400.0 mg
Oral, Tablet, extended release - Oral, Capsule - Oral, , Tablet, film coated, extended release - Oral, Capsule, Capsule, gelatin coated - Oral, Solution, Tablet, extended release, Tablet, Tablet - Oral, Capsule, gelatin coated, Tablet, film coated, extended release, Solution - Oral
Acute Coryza
150.0 mg, 450.0 mg, 300.0 mg, 8.0 meq/mL, , 600.0 mg, 250.0 mg, 400.0 mg
Oral, Tablet, extended release - Oral, Capsule - Oral, , Tablet, film coated, extended release - Oral, Capsule, Capsule, gelatin coated - Oral, Solution, Tablet, extended release, Tablet, Tablet - Oral, Capsule, gelatin coated, Tablet, film coated, extended release, Solution - Oral
Warnings
Eskalith Cr has one contraindication and should not be taken along with any of the conditions provided in the following table.Eskalith Cr ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Lithium Carbonate may interact with Toxoplasma Infections
Common Eskalith Cr Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Lithium carbonate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Lithium carbonate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Lithium carbonate is combined with Neomycin.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Lithium carbonate is combined with Oliceridine.
Sodium oxybate
Major
Lithium carbonate may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Eskalith Cr Toxicity & Overdose RiskTests with rats have found that the toxic dose of lithium carbonate is 525mg/kg when taken orally. The effects of lithium carbonate on fertility, cancer, and mutation have not been fully studied yet. Studies with animals have shown that too much lithium can affect male reproductive organs, sperm production, and testosterone levels. There is conflicting evidence about the effects of lithium during the first trimester of pregnancy. If a pregnant woman needs to take lithium, their dosage should be closely monitored and decreased or stopped a few days before giving birth. It is not recommended to breastfeed while taking lithium, but if someone does, the baby should be monitored
Eskalith Cr Novel Uses: Which Conditions Have a Clinical Trial Featuring Eskalith Cr?
Two active clinical trials are evaluating the potential of Eskalith Cr to ameliorate Acute Coryza.Condition
Clinical Trials
Trial Phases
Acute Coryza
1 Actively Recruiting
Not Applicable
Behcet Syndrome
2 Actively Recruiting
Not Applicable
Eskalith Cr Reviews: What are patients saying about Eskalith Cr?
5Patient Review
11/11/2010 I've tried a lot of different medications over the years, and this one is definitely the most effective. It's tough on your body, but it really does work. Maybe not in the way you would expect, but it does help to level you out as much as possible.
4.3Patient Review
2/27/2009 I was on this medication for around 6 months, but it didn't help me as much as I thought it would. I've since tried other medications (Ativan and Strattera) that have worked better for me.
4.3Patient Review
11/28/20074Patient Review
10/2/2009 I've been taking this medication for 12 years to manage my mania, and it's been fairly effective with only a few side effects.
4Patient Review
12/30/20074Patient Review
1/10/20083.7Patient Review
7/13/2008 I've been on this medication for a year now and, to be honest, I haven't seen much of a difference.
3.7Patient Review
11/16/20072.7Patient Review
3/26/2008 I'm taking this drug along with Zyprexa and it's working much better than just Zyprexa alone. I'm pretty content with the results.
Patient Q&A Section about eskalith cr
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Eskalith the same as lithium?
"Eskalith is lithium carbonate that is immediate release and supplied in 300 mg capsules. Eskalith CR is a slow release version of lithium carbonate that is supplied in 450 mg scored, breakable tablets."
Answered by AI
What is the generic name for Eskalith?
"Lithium is a medication used to treat mental health disorders and is available under the brand names Eskalith and Lithobid."
Answered by AI
What is Eskalith used for?
"ESKALITH is indicated for the treatment of manic episodes of manic-depressive illness. Maintenance therapy with ESKALITH can help prevent or lessen the intensity of future episodes in patients with a history of mania."
Answered by AI
Is Eskalith a mood stabilizer?
"Although the way lithium works to stabilize a person's mood is not known, it is known that it affects the central nervous system. This then leads to the person being able to better control their emotions and cope with the problems of living. It is important that both the person taking the lithium and their family understand the different effects it can have."
Answered by AI