Arthroplasty for Infection

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
InfectionArthroplasty - Procedure
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether one dose of antibiotics is as effective as one dose of antibiotics plus intra-articular antibiotics for preventing infection in primary or revision THA/TKA patients.

Treatment Effectiveness

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: 2 years

2 years
Long-term infection rate
Primary vs revision
Risk factor
Surgery time
3 months
Communicable Diseases
baseline, 1 year
EQ-5D-5L
The Western Ontario and McMaster Universities Arthritis Index (WOMAC)

Trial Safety

Trial Design

2 Treatment Groups

Standard
1 of 2
Vanco
1 of 2

Active Control

Experimental Treatment

1832 Total Participants · 2 Treatment Groups

Primary Treatment: Arthroplasty · No Placebo Group · N/A

Vanco
Procedure
Experimental Group · 1 Intervention: Arthroplasty · Intervention Types: Procedure
Standard
Procedure
ActiveComparator Group · 1 Intervention: Arthroplasty · Intervention Types: Procedure
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Arthroplasty
2013
Completed Phase 4
~30

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 2 years

Who is running the clinical trial?

Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de MontrealLead Sponsor
4 Previous Clinical Trials
1,379 Total Patients Enrolled
Benoit Benoit, MDPrincipal InvestigatorCIUSSS du Nord de l'Île de Montreal

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a diagnosis of osteoarthritis, osteonecrosis, or arthritis.
You are free of or treated for medical conditions that would pose excessive operative risk.