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What is Dopram
DoxapramThe Generic name of this drug
Treatment SummaryA medication that helps to increase breathing rate for a short period of time.
Dopramis the brand name
Dopram Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dopram
Doxapram
1965
4
Effectiveness
How Dopram Affects PatientsDoxapram is a drug that helps to stimulate the central nervous system. It increases the amount of air breathed in, and can raise blood pressure if there is no heart issue. The increase in blood pressure is caused by improved blood flow rather than the narrowing of blood vessels. After taking doxapram, there is usually a higher release of hormones in the body.
How Dopram works in the bodyDoxapram stimulates breathing by blocking potassium channels in your carotid body, which is a sensory organ that monitors your blood oxygen levels.
When to interrupt dosage
The quantity of Dopram is dependent upon the indicated condition, such as Acoustic Stimulation, post-operative respiratory stimulation therapy and Anesthetic complication pulmonary. The dose also relies on the technique of delivery (e.g. Injection or Injection - Intravenous) detailed in the table below.Condition
Dosage
Administration
Respiratory Depression
20.0 mg/mL,
, Intravenous, Injection, Injection - Intravenous, Liquid - Intravenous, Liquid
Chronic Obstructive Pulmonary Disease
20.0 mg/mL,
, Intravenous, Injection, Injection - Intravenous, Liquid - Intravenous, Liquid
Hypercapnia
20.0 mg/mL,
, Intravenous, Injection, Injection - Intravenous, Liquid - Intravenous, Liquid
postoperative respiratory depression
20.0 mg/mL,
, Intravenous, Injection, Injection - Intravenous, Liquid - Intravenous, Liquid
Anesthetic complication pulmonary
20.0 mg/mL,
, Intravenous, Injection, Injection - Intravenous, Liquid - Intravenous, Liquid
post-operative respiratory stimulation therapy
20.0 mg/mL,
, Intravenous, Injection, Injection - Intravenous, Liquid - Intravenous, Liquid
Warnings
Dopram has fifteen contraindications, so it should not be undertaken when encountering any of the conditions shown in the following table.Dopram ContraindicationsCondition
Risk Level
Notes
Tissue Expansion
Do Not Combine
respiration restriction
Do Not Combine
Chest wall structure
Do Not Combine
cardiovascular impairment
Do Not Combine
Severe Coronary Artery Disease
Do Not Combine
Stroke
Do Not Combine
Heart Decompensation
Do Not Combine
Severe Hypertension
Do Not Combine
convulsive disorders
Do Not Combine
Jaundice, Obstructive
Do Not Combine
Pulmonary Embolism
Do Not Combine
Suspected Pulmonary Embolism
Do Not Combine
Epilepsies
Do Not Combine
Brain
Do Not Combine
Muscle Tissue
Do Not Combine
Common Dopram Drug Interactions
Drug Name
Risk Level
Description
1-benzylimidazole
Minor
The risk or severity of hypertension can be increased when Doxapram is combined with 1-benzylimidazole.
2,5-Dimethoxy-4-ethylamphetamine
Minor
The risk or severity of hypertension can be increased when Doxapram is combined with 2,5-Dimethoxy-4-ethylamphetamine.
2,5-Dimethoxy-4-ethylthioamphetamine
Minor
The risk or severity of hypertension can be increased when Doxapram is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamine
Minor
The risk or severity of hypertension can be increased when Doxapram is combined with 4-Bromo-2,5-dimethoxyamphetamine.
4-Methoxyamphetamine
Minor
The risk or severity of hypertension can be increased when Doxapram is combined with 4-Methoxyamphetamine.
Dopram Toxicity & Overdose RiskThe most toxic dose of the drug in mice and rats is 75mg/kg and 40-80mg/kg in cats and dogs. Signs of overdosing include high blood pressure, fast heartbeat, increased muscle activity, and more active reflexes.
Dopram Novel Uses: Which Conditions Have a Clinical Trial Featuring Dopram?
98 investigations are presently underway to gauge the potential of Dopram in alleviating Anesthetic-induced Pulmonary Complication, Chronic Obstructive Pulmonary Disease (COPD) and Respiratory Depression.Condition
Clinical Trials
Trial Phases
Chronic Obstructive Pulmonary Disease
101 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Anesthetic complication pulmonary
0 Actively Recruiting
post-operative respiratory stimulation therapy
0 Actively Recruiting
Hypercapnia
0 Actively Recruiting
postoperative respiratory depression
0 Actively Recruiting
Respiratory Depression
0 Actively Recruiting
Patient Q&A Section about dopram
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What type of drug is doxapram?
"Doxapram is a central nervous system stimulant that increases tidal volume and slightly increases respiratory rate. It may also cause a pressor response."
Answered by AI
Is Dopram the same as doxapram?
"Doxapram hydrochloride is a drug that is used to stimulate the respiratory system. It is given intravenously, and increases the tidal volume and respiratory rate."
Answered by AI
Is doxapram still used?
"Doxapram has been used mostly in clinical areas involving patients who need intensive care, such as after surgery or childbirth, or in a neonatal intensive care unit."
Answered by AI
What is Dopram used for?
"Doxapram is a respiratory stimulant that is used to treat drug-induced ventilatory depression and apnoea in newborn animals and humans."
Answered by AI