Multidisciplinary Clinic Evaluation for Sarcopenia Due to COPD
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores new methods to diagnose and treat sarcopenia, the loss of muscle mass, in individuals with COPD, a lung disease. The trial compares the outcomes of a specialized clinic with a team of experts (Implementation of a Sarcopenia Clinic) to the usual care patients receive. Researchers aim to determine if this new approach can help patients gain muscle and improve their health, thereby reducing hospital visits and flare-ups. The trial seeks participants who have been hospitalized for COPD, have lower muscle mass as seen on a CT scan, and have a history of heavy smoking. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance future care for COPD patients.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this multidisciplinary clinic approach is safe for diagnosing and treating sarcopenia in COPD patients?
Research shows that the multidisciplinary sarcopenia clinic aims to help people with COPD and muscle loss feel better. Some studies suggest that this type of clinic could help manage symptoms and improve quality of life. The clinic uses a team of specialists, such as lung doctors and nurses, to provide comprehensive care.
Regarding safety, previous research has not shown any clear evidence of harmful side effects from this clinic model. Since the trial is in an early phase, the treatment is likely considered safe enough for human testing. The studies reviewed have not reported any major adverse events (serious side effects).
So far, the approach seems well-tolerated, meaning most people can handle it without problems. However, discussing the risks and benefits with a healthcare provider before joining any trial is always important.12345Why are researchers excited about this trial?
Researchers are excited about the implementation of a Sarcopenia Clinic for people with COPD because it offers a new, comprehensive approach to tackling muscle loss associated with the condition. Unlike traditional treatments that primarily focus on medication and pulmonary rehabilitation, this clinic combines expertise from various specialties to address sarcopenia from multiple angles. By integrating nutrition, exercise, and medical management, the Sarcopenia Clinic aims to not just slow muscle loss, but potentially improve muscle mass and strength more effectively than current standard care clinics.
What evidence suggests that this multidisciplinary clinic approach is effective for sarcopenia due to COPD?
Research shows that muscle loss, known as sarcopenia, is common and serious for people with COPD, a lung disease. Studies indicate that sarcopenia can worsen lung function and lead to more hospital visits. This trial will compare two approaches: a multidisciplinary sarcopenia clinic and a COPD standard of care clinic. A team-based approach, as used in the sarcopenia clinic, may improve muscle mass and overall health. Evidence suggests that these clinics, which include experts like doctors, nurses, and pharmacists, can improve outcomes for COPD patients. The goal is to increase muscle strength and reduce hospital visits. Early findings are promising, showing that sarcopenia is treatable, which could lead to better health for those with COPD.12678
Who Is on the Research Team?
Amy Attaway, MD
Principal Investigator
The Cleveland Clinic
Are You a Good Fit for This Trial?
This trial is for COPD patients over 40 who've been hospitalized due to a COPD exacerbation, have low muscle mass shown by CT scans, and have moderate lung obstruction. They must have a history of significant smoking (at least 10 pack years).Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are enrolled in either the multidisciplinary sarcopenia clinic or the standard ambulatory COPD clinic for treatment and monitoring
Follow-up
Participants are monitored for safety and effectiveness after treatment, including skeletal muscle mass, mortality, hospitalizations, and COPD exacerbations
What Are the Treatments Tested in This Trial?
Interventions
- Implementation of a Sarcopenia Clinic
Find a Clinic Near You
Who Is Running the Clinical Trial?
The Cleveland Clinic
Lead Sponsor