← Back to Search

tDCS for Cognitive Improvement in Healthy Subjects

N/A

Recruiting

Research Sponsored by University of California, Davis

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

between ages of 18 and 50

ability to give valid informed consent

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an average of 1 month

Awards & highlights

Study Summary

This trial will explore how stimulating brain regions with tDCS can improve higher-order cognitive skills in healthy and schizophrenia patients. EEGs and behavior tests will be used to assess performance.

Who is the study for?

This trial is for healthy individuals aged 18-50 who speak and understand English well enough to complete cognitive tasks. They must be able to consent to the study. People with head trauma, psychotropic medication use, poor vision without correction, or conditions that contraindicate tDCS/MRI (like pregnancy or metal in the body) cannot participate.Check my eligibility

What is being tested?

The study tests how transcranial direct current stimulation (tDCS) affects higher-order cognition like language comprehension and memory in healthy people and those with schizophrenia. It compares effects of stimulating different brain regions using behavioral tasks and EEG monitoring.See study design

What are the potential side effects?

Potential side effects of tDCS may include discomfort at the electrode sites, itching, tingling during application, headache, fatigue, nausea or other mild sensations but are generally considered minimal.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 50 years old.

Select...

I understand the study and can agree to participate.

Select...

I understand the study and can agree to participate.

Select...

I am between 18 and 50 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an average of 1 month

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an average of 1 month

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Behavioral Attention Lapse Measures on the Change Detection Task

Behavioral Attention Lapse Measures on the Stroop Task

Behavioral Cognitive Control Measures on the Change Detection Task Behavioral Cognitive Control Measures on the Change Detection Task

+6 more

Side effects data

From 2021 Phase 2 & 3 trial • 160 Patients • NCT02483468

Car accident

skin irritation

100%

80%

60%

40%

20%

Study treatment Arm

tDCS (Active)

tDCS (Sham)

Trial Design

3Treatment groups

Experimental Treatment

Placebo Group

Group I: Occipital StimulationExperimental Treatment1 Intervention

Intervention. 20 minutes of 2 mA direct current stimulation over the occipital cortex.

Group II: DLPFC StimulationExperimental Treatment1 Intervention

Intervention. 20 minutes of 2 mA direct current stimulation over the dorsolateral prefrontal cortex.

Group III: Sham StimulationPlacebo Group1 Intervention

Placebo Comparator. 0.5-1 minutes of 2 mA direct current stimulation over the dorsolateral prefrontal cortex followed by 19-19.5 minutes of sham stimulation

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Transcranial Direct Current Stimulation

2014

Completed Phase 3

~1100

0 / 4Eligibility criteria met