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What is Dexmethylphenidate Hydrochloride
DexmethylphenidateThe Generic name of this drug
Treatment SummaryDexmethylphenidate is a stimulant medication used to treat Attention Deficit Hyperactivity Disorder (ADHD). It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and was introduced in 2002. It is the dextrorotary form of methylphenidate and is thought to be more effective than the l-isomer or the racemic mixture and have fewer side effects.
Ritalinis the brand name
Dexmethylphenidate Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ritalin
Dexmethylphenidate
1955
400
Approved as Treatment by the FDA
Dexmethylphenidate, otherwise known as Ritalin, is approved by the FDA for 1 uses including Attention Deficit Hyperactivity Disorder .Attention Deficit Hyperactivity Disorder
Helps manage Attention Deficit Hyperactivity Disorder (ADHD)
Effectiveness
How Dexmethylphenidate Hydrochloride Affects PatientsDexmethylphenidate is a form of the drug methylphenidate, which is more active in the body than the regular version. It works by preventing norepinephrine and dopamine from being taken up in the brain.
How Dexmethylphenidate Hydrochloride works in the bodyMethylphenidate works by preventing dopamine and norepinephrine from being reabsorbed into brain cells. This means that more of these chemicals can be present in the brain for a longer period of time. Studies have shown that this can result in increased blood flow to certain parts of the brain, such as the striatum, supplementary motor area, and posterior parietal cortex.
When to interrupt dosage
The quantity of Dexmethylphenidate Hydrochloride is based on the diagnosed condition. The dosage fluctuates depending on the administration technique (e.g. Tablet, film coated, extended release or Capsule, extended release) indicated in the table below.Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 15.0 mg, 25.0 mg, 35.0 mg, 2.5 mg, 10.0 mg/mL, 5.0 mg/mL, 18.0 mg, 36.0 mg, 27.0 mg, 54.0 mg, 72.0 mg, 85.0 mg, 55.0 mg, 45.0 mg, 70.0 mg, 80.0 mg, 60.0 mg, 100.0 mg, 50.0 mg, 10.4 mg, 6.0 mg/mL, 5.2 mg, 9.0 mg/mL, 30.0 mg/mL, 7.5 mg/mL, 7.8 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Solution - Oral, Solution, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Tablet, Chewable, Extended Release, Suspension, extended release, Tablet, Chewable, Extended Release - Oral, Suspension, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Warnings
Dexmethylphenidate Hydrochloride ContraindicationsCondition
Risk Level
Notes
Gilles de la Tourette syndrome
Do Not Combine
Tension-Type Headache
Do Not Combine
Agitation
Do Not Combine
Pulse Frequency
Do Not Combine
Tourette Syndrome
Do Not Combine
Tics
Do Not Combine
Generalized Anxiety Disorder
Do Not Combine
Open-angle glaucoma
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Dexmethylphenidate may interact with Pulse Frequency
Common Dexmethylphenidate Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Desflurane
Major
Dexmethylphenidate may increase the hypertensive activities of Desflurane.
Diethyl ether
Major
Dexmethylphenidate may increase the hypertensive activities of Diethyl ether.
Enflurane
Major
Dexmethylphenidate may increase the hypertensive activities of Enflurane.
Ethanol
Major
Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Dexmethylphenidate Hydrochloride Toxicity & Overdose RiskDexmethylphenidate has the same effect in men and women. It is unclear if there are different effects on different races, children under 6 years old, people with kidney or liver problems, pregnant or breastfeeding women, or elderly people. Kidney issues should not affect the dose of dexmethylphenidate as it is not mainly cleared by the kidneys. Animal studies have shown that taking this drug during pregnancy can slow down the development of bones in the fetus, and can lead to reduced weight gain in male offspring. The benefits and risks should be carefully weighed before taking this drug. Animal studies suggest that dexmethylphenidate may cause liver tumors and
Dexmethylphenidate Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Dexmethylphenidate Hydrochloride?
77 active investigations are examining the potential of Dexmethylphenidate Hydrochloride to manage Attention Deficit Hyperactivity Disorder.Condition
Clinical Trials
Trial Phases
Attention Deficit Hyperactivity Disorder
65 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 2, Phase 1, Early Phase 1
Dexmethylphenidate Hydrochloride Reviews: What are patients saying about Dexmethylphenidate Hydrochloride?
5Patient Review
2/19/2015 I only get headaches every once in a while, and I actually lost weight in the first few months. However, that has since leveled off.
5Patient Review
2/19/2015 I only got occasional headaches from this treatment, and I actually lost a few pounds in the first few months. It's been really great!
4.7Patient Review
2/19/2014 I've tried a lot of different treatments for my son's ADHD, and this one seems to be working the best so far. He's on 20mg in the morning and another 20mg at lunchtime, five hours later. No problems with side effects that we can tell.
4.7Patient Review
2/19/2014 I've tried a lot of different treatments for my son's ADHD, and this one seems to be working better than the others. I'm hesitant to increase the dosage as recommended by his doctor, but so far he's been doing well on it.
4Patient Review
8/1/2015 This medication has helped me be able to focus on my work, school, and family life. I would recommend it to other adults who have trouble focusing.
Patient Q&A Section about dexmethylphenidate hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is dexmethylphenidate a Ritalin?
"Derivatives of methylphenidate (Ritalin, Concerta, Metadate, etc.) include dexmethylphenidate, which is a man-made stimulant."
Answered by AI
Is dexmethylphenidate hydrochloride the same as Adderall?
"Adderall and Focalin differ in that Adderall contains four types of amphetamine salt, while Focalin only contains one. Another key difference is that there is no generic form of Vyvanse, making it more expensive than Adderall."
Answered by AI
What does dexmethylphenidate hydrochloride do?
"Dexmethylphenidate is a medication used to treat attention deficit hyperactivity disorder (ADHD). It is classified as a central nervous system (CNS) stimulant. Dexmethylphenidate works by increasing attention and decreasing restlessness in patients who are hyperactive, have difficulty concentrating, or are easily distracted."
Answered by AI
Is dexmethylphenidate hydrochloride a narcotic?
"Focalin is a Schedule II controlled substance in the U.S., meaning it has a high potential for abuse and dependence."
Answered by AI
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