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What is Dexmethylphenidate Hydrochloride
DexmethylphenidateThe Generic name of this drug
Treatment SummaryDexmethylphenidate is a stimulant medication used to treat Attention Deficit Hyperactivity Disorder (ADHD). It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and was introduced in 2002. It is the dextrorotary form of methylphenidate and is thought to be more effective than the l-isomer or the racemic mixture and have fewer side effects.
Ritalinis the brand name
Dexmethylphenidate Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ritalin
Dexmethylphenidate
1955
400
Approved as Treatment by the FDA
Dexmethylphenidate, otherwise known as Ritalin, is approved by the FDA for 1 uses including Attention Deficit Hyperactivity Disorder .Attention Deficit Hyperactivity Disorder
Helps manage Attention Deficit Hyperactivity Disorder (ADHD)
Effectiveness
How Dexmethylphenidate Hydrochloride Affects PatientsDexmethylphenidate is a form of the drug methylphenidate, which is more active in the body than the regular version. It works by preventing norepinephrine and dopamine from being taken up in the brain.
How Dexmethylphenidate Hydrochloride works in the bodyMethylphenidate works by preventing dopamine and norepinephrine from being reabsorbed into brain cells. This means that more of these chemicals can be present in the brain for a longer period of time. Studies have shown that this can result in increased blood flow to certain parts of the brain, such as the striatum, supplementary motor area, and posterior parietal cortex.
When to interrupt dosage
The quantity of Dexmethylphenidate Hydrochloride is based on the diagnosed condition. The dosage fluctuates depending on the administration technique (e.g. Tablet, film coated, extended release or Capsule, extended release) indicated in the table below.Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 15.0 mg, 25.0 mg, 35.0 mg, 2.5 mg, 10.0 mg/mL, 5.0 mg/mL, 18.0 mg, 36.0 mg, 27.0 mg, 54.0 mg, 72.0 mg, 85.0 mg, 55.0 mg, 45.0 mg, 70.0 mg, 80.0 mg, 60.0 mg, 100.0 mg, 50.0 mg, 10.4 mg, 6.0 mg/mL, 5.2 mg, 9.0 mg/mL, 30.0 mg/mL, 7.5 mg/mL, 7.8 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Capsule - Oral, Capsule, Solution - Oral, Solution, Tablet, chewable, Tablet, extended release - Oral, Tablet, extended release, Tablet, chewable - Oral, Tablet, Chewable, Extended Release, Suspension, extended release, Tablet, Chewable, Extended Release - Oral, Suspension, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Warnings
Dexmethylphenidate Hydrochloride ContraindicationsCondition
Risk Level
Notes
Gilles de la Tourette syndrome
Do Not Combine
Tension
Do Not Combine
Agitation
Do Not Combine
Pulse Frequency
Do Not Combine
diagnosed tourette's syndrome
Do Not Combine
Tic, Motor
Do Not Combine
Generalized Anxiety Disorder
Do Not Combine
Open-angle glaucoma
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Dexmethylphenidate may interact with Pulse Frequency
Common Dexmethylphenidate Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Desflurane
Major
Dexmethylphenidate may increase the hypertensive activities of Desflurane.
Diethyl ether
Major
Dexmethylphenidate may increase the hypertensive activities of Diethyl ether.
Enflurane
Major
Dexmethylphenidate may increase the hypertensive activities of Enflurane.
Ethanol
Major
Dexmethylphenidate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Dexmethylphenidate Hydrochloride Toxicity & Overdose RiskDexmethylphenidate has the same effect in men and women. It is unclear if there are different effects on different races, children under 6 years old, people with kidney or liver problems, pregnant or breastfeeding women, or elderly people. Kidney issues should not affect the dose of dexmethylphenidate as it is not mainly cleared by the kidneys. Animal studies have shown that taking this drug during pregnancy can slow down the development of bones in the fetus, and can lead to reduced weight gain in male offspring. The benefits and risks should be carefully weighed before taking this drug. Animal studies suggest that dexmethylphenidate may cause liver tumors and
Dexmethylphenidate Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Dexmethylphenidate Hydrochloride?
77 active investigations are examining the potential of Dexmethylphenidate Hydrochloride to manage Attention Deficit Hyperactivity Disorder.Condition
Clinical Trials
Trial Phases
Attention Deficit Hyperactivity Disorder
71 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Dexmethylphenidate Hydrochloride Reviews: What are patients saying about Dexmethylphenidate Hydrochloride?
5Patient Review
2/19/2015 I only get headaches every once in a while, and I actually lost weight in the first few months. However, that has since leveled off.
5Patient Review
2/19/2015 I only got occasional headaches from this treatment, and I actually lost a few pounds in the first few months. It's been really great!
4.7Patient Review
2/19/2014 I've tried a lot of different treatments for my son's ADHD, and this one seems to be working the best so far. He's on 20mg in the morning and another 20mg at lunchtime, five hours later. No problems with side effects that we can tell.
4.7Patient Review
2/19/2014 I've tried a lot of different treatments for my son's ADHD, and this one seems to be working better than the others. I'm hesitant to increase the dosage as recommended by his doctor, but so far he's been doing well on it.
4Patient Review
8/1/2015 This medication has helped me be able to focus on my work, school, and family life. I would recommend it to other adults who have trouble focusing.
4Patient Review
8/1/2015 This medication helped me be able to focus a lot better. I'm now able to work full-time, take care of my three kids, and still have time to work on my degree plans. I definitely noticed a difference in how well I was able to pay attention to details and get things done.
3.7Patient Review
5/1/2015 We've been using Focalin XR for a little over a year now. It's helped my son, but he has zero appetite while the drug is active (which lasts about 7 hours). Additionally, his hyperactivity gets worse after the effects of the medication wear off. We had to start giving him Melatonin at night so that he could settle down and sleep. We're currently investigating other options for longer-term treatment.
3.7Patient Review
10/16/2014 My son was prescribed Ritalin, but it would wear off too quickly and he'd lose focus in school. His doctor recommended Focalin as a time-release option, and we've seen great results so far. He hasn't had any changes to his sleep or eating patterns, and there haven't been any negative side effects that we've noticed.
3.7Patient Review
4/17/2014 My son has been on this medication for eight months. The first few were great, but then he started becoming irritable and developed anxiety and thoughts of harming himself. I'm looking to switch medications, but his doctor seems to think we can power through these side effects.
3.7Patient Review
4/17/2014 My son has been on this medication for eight months. At first, it was going great; however, a few months ago I started to notice his irritability. He's also developed anxiety and now he's having harmful thoughts of hurting himself. An 8-year-old shouldn't be experiencing these things.
3.7Patient Review
5/1/2015 My son has been taking Focalin XR for a little over a year now. I am satisfied for the most part; however, he has complete lack of appetite for the 7 hours the drug actually works (compensating in the evenings by eating 3 plates at dinner). In addition, his hyperactivity after the drug wears off is significantly increased. We had to start him on Melatonin at night to settle his mind and get him to sleep. We are looking into a longer lasting medication.
3.7Patient Review
10/16/2014 So far, this has been a much better option for my son than Ritalin. He's able to focus longer and there haven't been any negative side effects that we've seen.
3.3Patient Review
2/19/2014 I was diagnosed with ADHD and this treatment has helped me a lot.
3.3Patient Review
2/19/2014 this helps with my adhd but i still have some problems
3Patient Review
7/29/2014 I took this at 2pm and by 3pm, just one hour later, I noticed it wearing off. I was disappointed because I thought XR meant it was time-released.
3Patient Review
7/29/2014 I first took this medication at 2pm, and by 3pm I noticed it wearing off. Maybe it just didn't work well for me, but I was expecting the XR version to last longer since it's supposed to be time-released.
2.7Patient Review
8/21/2014 I saw no change in my daughter after using this treatment. If anything, it made her more lost and unattentive.
2.7Patient Review
8/21/2014 I saw no real change in my daughter after using this treatment. If anything, she seemed more lost and unattentive than before.
2.3Patient Review
1/25/2022 I didn't enjoy this medication from the start. It also doesn't last very long, which is frustrating. I feel nauseous and down when it wears off, so I'm not looking forward to trying a different variation of this drug.
2.3Patient Review
8/3/2022 This medicine had some short-term benefits, but after a while, I started to lose weight and look very sick. I was more focused, but I wasn't my usual happy self. I felt like a zombie.
2.3Patient Review
1/25/2022 I didn't enjoy this medication from the start. It also only lasted for a few hours, which was frustrating. Additionally, I felt nauseous and down when it wore off. My doctor wants me to try regular Focalin next, but I'm not hopeful that it will be any better.
2.3Patient Review
8/3/2022 I tried this treatment as a child at the suggestion of my mother. It was effective for a short while, but then I started losing weight and looking very sick. I wasn't myself at all while taking this medication; rather, I felt like a zombie.
2Patient Review
6/24/2014 My child has been dealing with a lot of anxiety and fearfulness.
2Patient Review
6/24/2014 My child has been very anxious and fearful
1.7Patient Review
4/7/2021 This was a big help in terms of calming my mind, but I started experiencing some very severe mood swings. Once I stopped taking the medication, those feelings went away.
1.7Patient Review
4/7/2021 This was a marked improvement from other common stimulants I had tried, in that it actually helped to calm my mind. For the first time in a long while, my thoughts were quiet and at peace. However, I started experiencing severe mood swings in the evening hours; becoming enraged and throwing things. Once I was taken off the medication by my doctor, those feelings stopped entirely.
Patient Q&A Section about dexmethylphenidate hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is dexmethylphenidate a Ritalin?
"Derivatives of methylphenidate (Ritalin, Concerta, Metadate, etc.) include dexmethylphenidate, which is a man-made stimulant."
Answered by AI
Is dexmethylphenidate hydrochloride the same as Adderall?
"Adderall and Focalin differ in that Adderall contains four types of amphetamine salt, while Focalin only contains one. Another key difference is that there is no generic form of Vyvanse, making it more expensive than Adderall."
Answered by AI
What does dexmethylphenidate hydrochloride do?
"Dexmethylphenidate is a medication used to treat attention deficit hyperactivity disorder (ADHD). It is classified as a central nervous system (CNS) stimulant. Dexmethylphenidate works by increasing attention and decreasing restlessness in patients who are hyperactive, have difficulty concentrating, or are easily distracted."
Answered by AI
Is dexmethylphenidate hydrochloride a narcotic?
"Focalin is a Schedule II controlled substance in the U.S., meaning it has a high potential for abuse and dependence."
Answered by AI