What is Delsym
DoxylamineThe Generic name of this drug
Treatment SummaryDoxylamine is a medication that reduces the effects of histamine, a natural chemical in the body. It is used to treat allergies, coughing, nausea, and can also help people sleep. It has been used to treat animals and was once used to treat Parkinson's disease.
Unisom SleepTabsis the brand name
Delsym Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Unisom SleepTabs
Doxylamine
1978
82
Approved as Treatment by the FDA
Doxylamine, also known as Unisom SleepTabs, is approved by the FDA for 4 uses like Nausea and Vomiting and Symptoms Flu .Nausea and Vomiting
Used to treat Vomiting in combination with Pyridoxine
Symptoms Flu
Used in combination with Doxylamine for Symptoms Flu
Catarrh
Used in combination with Doxylamine for Common Cold
Gastrointestinal distress
Used to treat Nausea in combination with Pyridoxine
Effectiveness
How Delsym Affects PatientsDoxylamine is an antihistamine commonly used to help people sleep and relieve symptoms of allergies like hay fever and hives. It is more effective than most other antihistamines available, with the exception of diphenhydramine (Benadryl). It is also more powerful than many prescription sleep aids. Studies have shown it to be more effective for sleep aid than even the barbiturate, phenobarbital. Doxylamine is also a strong anticholinergic.
How Delsym works in the bodyDoxylamine helps reduce allergy symptoms by blocking histamine from attaching to cells. It also has calming and muscle-relaxing properties.
When to interrupt dosage
The proposed measure of Delsym is contingent upon the specified condition, including Symptoms Flu, Nausea and Nausea and Vomiting. The amount of dosage fluctuates, in accordance with the method of administration noted in the table beneath.Condition
Dosage
Administration
Gastrointestinal distress
, 6.25 mg, 3.125 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 25.0 mg, 9.75 mg/mL, 1.0 mg/mL, 135.0 mg/mL, 20.0 mg, 6.25 mg/mL, 5.0 mg, 10.5 mg, 12.5 mg, 0.75 mg/mL, 7.5 mg/mL, 6.0 mg/mL, 1.2 mg/mL, 200.0 mg, 12.5 mg/mL, 0.4167 mg/mL, 1250.0 mg/mL, 6.5 mg, 7.5 mg, 9.78 mg/mL, 0.0125 mg/mg, 10.0 mg
Kit; Solution, , Powder, for solution - Oral, Liquid, Capsule, liquid filled, Syrup - Oral, Oral, Tablet, delayed release - Oral, Solution - Oral, Powder - Oral, Capsule, liquid filled - Oral, Tablet - Oral, Kit - Oral, Kit; Liquid - Oral, Kit, Tablet, effervescent - Oral, Syrup, Capsule, liquid filled; Kit, Solution, Tablet, film coated - Oral, Capsule - Oral, Tablet, extended release, Tablet, effervescent, Liquid - Oral, Capsule; Kit, Kit; Solution - Oral, Capsule, liquid filled; Kit - Oral, Kit; Suspension - Oral, Tablet, Powder, Kit; Liquid; Solution, Tablet, extended release - Oral, Tablet, chewable, Capsule; Kit - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit, Kit; Liquid, Capsule, gelatin coated - Oral, Kit; Tablet, film coated, Tablet, coated, Capsule, gelatin coated, Tablet, delayed release, Kit; Syrup - Oral, Capsule, Kit; Liquid; Solution - Oral, Kit; Tablet - Oral, Tablet, coated - Oral, Kit; Tablet, Kit; Syrup, Tablet, film coated, Kit; Tablet; Tablet, coated, Powder, for solution, Tablet, chewable - Oral, Kit; Powder, for solution - Oral, Kit; Powder, for solution, Kit; Tablet, film coated - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit - Oral, Kit; Suspension, Kit; Tablet; Tablet, coated - Oral
Symptoms Flu
, 6.25 mg, 3.125 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 25.0 mg, 9.75 mg/mL, 1.0 mg/mL, 135.0 mg/mL, 20.0 mg, 6.25 mg/mL, 5.0 mg, 10.5 mg, 12.5 mg, 0.75 mg/mL, 7.5 mg/mL, 6.0 mg/mL, 1.2 mg/mL, 200.0 mg, 12.5 mg/mL, 0.4167 mg/mL, 1250.0 mg/mL, 6.5 mg, 7.5 mg, 9.78 mg/mL, 0.0125 mg/mg, 10.0 mg
Kit; Solution, , Powder, for solution - Oral, Liquid, Capsule, liquid filled, Syrup - Oral, Oral, Tablet, delayed release - Oral, Solution - Oral, Powder - Oral, Capsule, liquid filled - Oral, Tablet - Oral, Kit - Oral, Kit; Liquid - Oral, Kit, Tablet, effervescent - Oral, Syrup, Capsule, liquid filled; Kit, Solution, Tablet, film coated - Oral, Capsule - Oral, Tablet, extended release, Tablet, effervescent, Liquid - Oral, Capsule; Kit, Kit; Solution - Oral, Capsule, liquid filled; Kit - Oral, Kit; Suspension - Oral, Tablet, Powder, Kit; Liquid; Solution, Tablet, extended release - Oral, Tablet, chewable, Capsule; Kit - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit, Kit; Liquid, Capsule, gelatin coated - Oral, Kit; Tablet, film coated, Tablet, coated, Capsule, gelatin coated, Tablet, delayed release, Kit; Syrup - Oral, Capsule, Kit; Liquid; Solution - Oral, Kit; Tablet - Oral, Tablet, coated - Oral, Kit; Tablet, Kit; Syrup, Tablet, film coated, Kit; Tablet; Tablet, coated, Powder, for solution, Tablet, chewable - Oral, Kit; Powder, for solution - Oral, Kit; Powder, for solution, Kit; Tablet, film coated - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit - Oral, Kit; Suspension, Kit; Tablet; Tablet, coated - Oral
Insomnia
, 6.25 mg, 3.125 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 25.0 mg, 9.75 mg/mL, 1.0 mg/mL, 135.0 mg/mL, 20.0 mg, 6.25 mg/mL, 5.0 mg, 10.5 mg, 12.5 mg, 0.75 mg/mL, 7.5 mg/mL, 6.0 mg/mL, 1.2 mg/mL, 200.0 mg, 12.5 mg/mL, 0.4167 mg/mL, 1250.0 mg/mL, 6.5 mg, 7.5 mg, 9.78 mg/mL, 0.0125 mg/mg, 10.0 mg
Kit; Solution, , Powder, for solution - Oral, Liquid, Capsule, liquid filled, Syrup - Oral, Oral, Tablet, delayed release - Oral, Solution - Oral, Powder - Oral, Capsule, liquid filled - Oral, Tablet - Oral, Kit - Oral, Kit; Liquid - Oral, Kit, Tablet, effervescent - Oral, Syrup, Capsule, liquid filled; Kit, Solution, Tablet, film coated - Oral, Capsule - Oral, Tablet, extended release, Tablet, effervescent, Liquid - Oral, Capsule; Kit, Kit; Solution - Oral, Capsule, liquid filled; Kit - Oral, Kit; Suspension - Oral, Tablet, Powder, Kit; Liquid; Solution, Tablet, extended release - Oral, Tablet, chewable, Capsule; Kit - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit, Kit; Liquid, Capsule, gelatin coated - Oral, Kit; Tablet, film coated, Tablet, coated, Capsule, gelatin coated, Tablet, delayed release, Kit; Syrup - Oral, Capsule, Kit; Liquid; Solution - Oral, Kit; Tablet - Oral, Tablet, coated - Oral, Kit; Tablet, Kit; Syrup, Tablet, film coated, Kit; Tablet; Tablet, coated, Powder, for solution, Tablet, chewable - Oral, Kit; Powder, for solution - Oral, Kit; Powder, for solution, Kit; Tablet, film coated - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit - Oral, Kit; Suspension, Kit; Tablet; Tablet, coated - Oral
Mild Allergic Rhinitis
, 6.25 mg, 3.125 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 25.0 mg, 9.75 mg/mL, 1.0 mg/mL, 135.0 mg/mL, 20.0 mg, 6.25 mg/mL, 5.0 mg, 10.5 mg, 12.5 mg, 0.75 mg/mL, 7.5 mg/mL, 6.0 mg/mL, 1.2 mg/mL, 200.0 mg, 12.5 mg/mL, 0.4167 mg/mL, 1250.0 mg/mL, 6.5 mg, 7.5 mg, 9.78 mg/mL, 0.0125 mg/mg, 10.0 mg
Kit; Solution, , Powder, for solution - Oral, Liquid, Capsule, liquid filled, Syrup - Oral, Oral, Tablet, delayed release - Oral, Solution - Oral, Powder - Oral, Capsule, liquid filled - Oral, Tablet - Oral, Kit - Oral, Kit; Liquid - Oral, Kit, Tablet, effervescent - Oral, Syrup, Capsule, liquid filled; Kit, Solution, Tablet, film coated - Oral, Capsule - Oral, Tablet, extended release, Tablet, effervescent, Liquid - Oral, Capsule; Kit, Kit; Solution - Oral, Capsule, liquid filled; Kit - Oral, Kit; Suspension - Oral, Tablet, Powder, Kit; Liquid; Solution, Tablet, extended release - Oral, Tablet, chewable, Capsule; Kit - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit, Kit; Liquid, Capsule, gelatin coated - Oral, Kit; Tablet, film coated, Tablet, coated, Capsule, gelatin coated, Tablet, delayed release, Kit; Syrup - Oral, Capsule, Kit; Liquid; Solution - Oral, Kit; Tablet - Oral, Tablet, coated - Oral, Kit; Tablet, Kit; Syrup, Tablet, film coated, Kit; Tablet; Tablet, coated, Powder, for solution, Tablet, chewable - Oral, Kit; Powder, for solution - Oral, Kit; Powder, for solution, Kit; Tablet, film coated - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit - Oral, Kit; Suspension, Kit; Tablet; Tablet, coated - Oral
Nausea and Vomiting
, 6.25 mg, 3.125 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 25.0 mg, 9.75 mg/mL, 1.0 mg/mL, 135.0 mg/mL, 20.0 mg, 6.25 mg/mL, 5.0 mg, 10.5 mg, 12.5 mg, 0.75 mg/mL, 7.5 mg/mL, 6.0 mg/mL, 1.2 mg/mL, 200.0 mg, 12.5 mg/mL, 0.4167 mg/mL, 1250.0 mg/mL, 6.5 mg, 7.5 mg, 9.78 mg/mL, 0.0125 mg/mg, 10.0 mg
Kit; Solution, , Powder, for solution - Oral, Liquid, Capsule, liquid filled, Syrup - Oral, Oral, Tablet, delayed release - Oral, Solution - Oral, Powder - Oral, Capsule, liquid filled - Oral, Tablet - Oral, Kit - Oral, Kit; Liquid - Oral, Kit, Tablet, effervescent - Oral, Syrup, Capsule, liquid filled; Kit, Solution, Tablet, film coated - Oral, Capsule - Oral, Tablet, extended release, Tablet, effervescent, Liquid - Oral, Capsule; Kit, Kit; Solution - Oral, Capsule, liquid filled; Kit - Oral, Kit; Suspension - Oral, Tablet, Powder, Kit; Liquid; Solution, Tablet, extended release - Oral, Tablet, chewable, Capsule; Kit - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit, Kit; Liquid, Capsule, gelatin coated - Oral, Kit; Tablet, film coated, Tablet, coated, Capsule, gelatin coated, Tablet, delayed release, Kit; Syrup - Oral, Capsule, Kit; Liquid; Solution - Oral, Kit; Tablet - Oral, Tablet, coated - Oral, Kit; Tablet, Kit; Syrup, Tablet, film coated, Kit; Tablet; Tablet, coated, Powder, for solution, Tablet, chewable - Oral, Kit; Powder, for solution - Oral, Kit; Powder, for solution, Kit; Tablet, film coated - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit - Oral, Kit; Suspension, Kit; Tablet; Tablet, coated - Oral
Catarrh
, 6.25 mg, 3.125 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 25.0 mg, 9.75 mg/mL, 1.0 mg/mL, 135.0 mg/mL, 20.0 mg, 6.25 mg/mL, 5.0 mg, 10.5 mg, 12.5 mg, 0.75 mg/mL, 7.5 mg/mL, 6.0 mg/mL, 1.2 mg/mL, 200.0 mg, 12.5 mg/mL, 0.4167 mg/mL, 1250.0 mg/mL, 6.5 mg, 7.5 mg, 9.78 mg/mL, 0.0125 mg/mg, 10.0 mg
Kit; Solution, , Powder, for solution - Oral, Liquid, Capsule, liquid filled, Syrup - Oral, Oral, Tablet, delayed release - Oral, Solution - Oral, Powder - Oral, Capsule, liquid filled - Oral, Tablet - Oral, Kit - Oral, Kit; Liquid - Oral, Kit, Tablet, effervescent - Oral, Syrup, Capsule, liquid filled; Kit, Solution, Tablet, film coated - Oral, Capsule - Oral, Tablet, extended release, Tablet, effervescent, Liquid - Oral, Capsule; Kit, Kit; Solution - Oral, Capsule, liquid filled; Kit - Oral, Kit; Suspension - Oral, Tablet, Powder, Kit; Liquid; Solution, Tablet, extended release - Oral, Tablet, chewable, Capsule; Kit - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit, Kit; Liquid, Capsule, gelatin coated - Oral, Kit; Tablet, film coated, Tablet, coated, Capsule, gelatin coated, Tablet, delayed release, Kit; Syrup - Oral, Capsule, Kit; Liquid; Solution - Oral, Kit; Tablet - Oral, Tablet, coated - Oral, Kit; Tablet, Kit; Syrup, Tablet, film coated, Kit; Tablet; Tablet, coated, Powder, for solution, Tablet, chewable - Oral, Kit; Powder, for solution - Oral, Kit; Powder, for solution, Kit; Tablet, film coated - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit - Oral, Kit; Suspension, Kit; Tablet; Tablet, coated - Oral
Pregnancy
, 6.25 mg, 3.125 mg/mL, 0.625 mg/mL, 1.25 mg/mL, 25.0 mg, 9.75 mg/mL, 1.0 mg/mL, 135.0 mg/mL, 20.0 mg, 6.25 mg/mL, 5.0 mg, 10.5 mg, 12.5 mg, 0.75 mg/mL, 7.5 mg/mL, 6.0 mg/mL, 1.2 mg/mL, 200.0 mg, 12.5 mg/mL, 0.4167 mg/mL, 1250.0 mg/mL, 6.5 mg, 7.5 mg, 9.78 mg/mL, 0.0125 mg/mg, 10.0 mg
Kit; Solution, , Powder, for solution - Oral, Liquid, Capsule, liquid filled, Syrup - Oral, Oral, Tablet, delayed release - Oral, Solution - Oral, Powder - Oral, Capsule, liquid filled - Oral, Tablet - Oral, Kit - Oral, Kit; Liquid - Oral, Kit, Tablet, effervescent - Oral, Syrup, Capsule, liquid filled; Kit, Solution, Tablet, film coated - Oral, Capsule - Oral, Tablet, extended release, Tablet, effervescent, Liquid - Oral, Capsule; Kit, Kit; Solution - Oral, Capsule, liquid filled; Kit - Oral, Kit; Suspension - Oral, Tablet, Powder, Kit; Liquid; Solution, Tablet, extended release - Oral, Tablet, chewable, Capsule; Kit - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit, Kit; Liquid, Capsule, gelatin coated - Oral, Kit; Tablet, film coated, Tablet, coated, Capsule, gelatin coated, Tablet, delayed release, Kit; Syrup - Oral, Capsule, Kit; Liquid; Solution - Oral, Kit; Tablet - Oral, Tablet, coated - Oral, Kit; Tablet, Kit; Syrup, Tablet, film coated, Kit; Tablet; Tablet, coated, Powder, for solution, Tablet, chewable - Oral, Kit; Powder, for solution - Oral, Kit; Powder, for solution, Kit; Tablet, film coated - Oral, Capsule, gelatin coated; Capsule, liquid filled; Kit - Oral, Kit; Suspension, Kit; Tablet; Tablet, coated - Oral
Warnings
There are 20 known major drug interactions with Delsym.Common Delsym Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Doxylamine is combined with Aclidinium.
Azelastine
Major
Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Doxylamine is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Doxylamine is combined with Eluxadoline.
Glycopyrronium
Major
The risk or severity of adverse effects can be increased when Doxylamine is combined with Glycopyrronium.
Delsym Toxicity & Overdose RiskSigns of an overdose on amoxicillin include wheezing, chest tightness, fever, itching, severe coughing, skin discoloration, seizures, and swelling of the face, lips, tongue, or throat.
Delsym Novel Uses: Which Conditions Have a Clinical Trial Featuring Delsym?
178 active trials are being conducted to determine the effectiveness of Delsym in alleviating Insomnia, Flu Symptoms and Catarrh.Condition
Clinical Trials
Trial Phases
Symptoms Flu
0 Actively Recruiting
Catarrh
2 Actively Recruiting
Phase 2, Not Applicable
Pregnancy
43 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 1, Phase 4
Insomnia
85 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3
Gastrointestinal distress
25 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1
Nausea and Vomiting
28 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 4, Phase 1
Mild Allergic Rhinitis
0 Actively Recruiting
Delsym Reviews: What are patients saying about Delsym?
5Patient Review
8/22/2016 I had no issues with this cough syrup. I slept soundly through the night and didn't experience any adverse effects. It also stopped my coughing fits during the day and night.
5Patient Review
12/1/2021 My wife recommended this product to help with my cough, and I'm so glad she did! It allowed me to sleep through the night, which was a huge relief. I didn't experience any negative side effects, so I would definitely take it again if needed.
3.7Patient Review
11/5/2014 Though it did stop my coughing, I would not recommend this medication. After taking it, I woke up just a few hours later feeling confused and jittery. Additionally, I experienced an upset stomach and have been dealing with the after-effects for a day now.
3.7Patient Review
1/12/2017 While this did help with my problem, it unfortunately also came with some less desirable side effects like an increased heart rate and blood pressure.
3.7Patient Review
9/3/2021 Delsym unfortunately raised my blood pressure after taking it just once. I was informed in the hospital emergency room not to take this again. Even now, some time later, my blood pressure is still higher than normal.
3.3Patient Review
1/5/2015 Delsym did stop my coughing at night, however I began vomiting and felt awful. It was like food poisoning! I'll never take this again.
3Patient Review
11/23/2014 I took the recommended amount and got a high off of it. I felt unreal and disconnected. I have never used drugs in my life but everyone told me that it sounded like I was high. I also felt nauseated!
2.7Patient Review
12/19/2014 This drug worked well during the day to suppress my cough, but I couldn't sleep at all when taking it at night.
2.7Patient Review
5/13/2016 Delsym stopped me from being able to poop for an entire week. It was really uncomfortable and caused a lot of problems. I don't think I'll be using this treatment again.
2.7Patient Review
4/14/2020 I lost my sense of taste and smell after taking this medication. My boss experienced the same thing.
2.3Patient Review
5/20/2015 I had a bad cough that got worse after taking this syrup. I ended up going to the ER where I received steroid injections and nebulizer treatment. Not worth it.
2.3Patient Review
3/2/2019 I took the recommended dose of this medication and, within a couple hours, had severe diarrhea. I also felt faint, nauseous, anxious, and experienced muscle spasms. This was easily the worst experience I've ever had--I would rather have kept the cough!
2Patient Review
12/5/2014 I had a cough that was disrupting my workday, so I went to the pharmacy and they recommended this product. It helped somewhat, but then I woke up in the middle of the night with a burning stomach and couldn't get back to sleep. As a result, I'm feeling awful today and can barely function.
2Patient Review
12/18/2016 I wasn't really impressed with this cough syrup. I can't tell if it's caused my loss of smell and taste, but that's been a problem since I started taking it.
1.7Patient Review
9/11/2019 Tessalon Perles are a godsend for those struggling with coughs. I'd definitely recommend seeing a doctor and getting a prescription for them.
1.7Patient Review
3/3/2015 My son several sleepless nights after taking this medicine. It seemed to make him more wired and hyperactive before I realized what was happening.
Patient Q&A Section about delsym
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Delsym good for a cough?
"Delsym and Robitussin can help relieve coughs temporarily, and are especially useful for non-productive coughs like those caused by the common cold or bronchitis. Dextromethorphan, the active ingredient found in both Delsym and Robitussin, can also be used to relieve pain associated with diabetic neuropathy, even though it's not officially approved for that use."
Answered by AI
What is the difference between mucinex and Delsym?
"Delsym is a good option for treating dry cough, as it breaks up mucus that causes the cough. However, it is not safe to take with MAO inhibitors. Mucinex is a useful medicine for loosening congestion in your chest and throat, and it lasts longer than other guaifenesin products."
Answered by AI
What is Delsym used for?
"Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses. Dextromethorphan is a cough suppressant that reduces the urge to cough. Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages, which can cause congestion."
Answered by AI
Will Delsym make me sleepy?
"Drowsiness, dizziness, nausea, and vomiting may occur with this medication. Rarely, people may experience severe drowsiness or dizziness. If you experience any of these side effects, tell your doctor or pharmacist immediately."
Answered by AI