What is Xyzal Allergy 24Hr
LevocetirizineThe Generic name of this drug
Treatment SummaryLevocetirizine is an antihistamine medication used to relieve symptoms of allergies. It is the “left-handed” version of cetirizine and has a stronger bond to histamine receptors. The drug was approved by the FDA in 1995.
Xyzalis the brand name
Xyzal Allergy 24Hr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Xyzal
Levocetirizine
2007
123
Approved as Treatment by the FDA
Levocetirizine, commonly known as Xyzal, is approved by the FDA for 3 uses which include Hay Fever and Chronic Urticaria .Hay Fever
Chronic Urticaria
Perennial Allergic Rhinitis (PAR)
Effectiveness
How Xyzal Allergy 24Hr Affects PatientsLevocetirizine is a type of medication used to reduce the symptoms of allergies. It is usually taken once per day, and is considered safe as it takes a large amount to cause harm. Patients should be aware that this drug can make them drowsy, so they should avoid activities that require them to be alert. Those with a higher risk of urinary retention should be especially cautious when taking levocetirizine.
How Xyzal Allergy 24Hr works in the bodyLevocetirizine helps prevent the effects of histamines in the body. Histamines are chemicals that cause muscle contractions, allow fluid to move through vascular walls, stimulate cough receptors, and create flare responses in the nervous system. Levocetirizine stops these effects by blocking histamine from binding to its receptor.
When to interrupt dosage
The suggested dosage of Xyzal Allergy 24Hr is contingent upon the diagnosed state, including Perennial Allergy, Chronic Idiopathic Urticaria and Perennial Allergic Rhinitis (PAR). The measure of dosage fluctuates, depending on the technique of delivery (e.g. Oral or Gel) depicted in the table underneath.Condition
Dosage
Administration
Perennial Allergic Rhinitis (PAR)
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Perennial Allergy
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Hay Fever
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Catarrh
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Chronic Urticaria
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Not responsive to other therapy
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Nasal Congestion
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Hay Fever
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Seasonal Allergies
5.0 mg, , 0.01 mg/mg, 0.02 mg/mg, 0.5 mg/mL, 2.5 mg/mL, 3.0 mg/mg, 1.0 mg/mg, 50.0 mg/mL
Oral, Gel, Tablet, film coated, Topical, Tablet, , Gel - Topical, Kit - Topical, Tablet, film coated - Oral, Tablet, coated, Tablet - Oral, Shampoo - Topical, Cream - Topical, Solution, Cream, Kit, Shampoo, Tablet, coated - Oral, Solution - Oral
Warnings
Xyzal Allergy 24Hr has three contraindications. It should never be combined with any of the conditions listed in the below table.Xyzal Allergy 24Hr ContraindicationsCondition
Risk Level
Notes
Hemodialysis
Do Not Combine
Kidney Failure
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Levocetirizine may interact with Toxoplasma Infections
Common Xyzal Allergy 24Hr Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Levocetirizine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Levocetirizine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Hydroxyzine.
Mobocertinib
Major
The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Mobocertinib.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Levocetirizine is combined with Oliceridine.
Xyzal Allergy 24Hr Toxicity & Overdose RiskSigns of an overdose on this drug include drowsiness and restlessness in children. Treatments should focus on supportive measures, as dialysis cannot be used to remove the drug from the body. The highest amount of this drug that can be taken without causing death in mice and rats is 240mg/kg.
Xyzal Allergy 24Hr Novel Uses: Which Conditions Have a Clinical Trial Featuring Xyzal Allergy 24Hr?
9 active clinical trials are ongoing to explore the utility of Xyzal Allergy 24Hr in providing relief from Chronic Idiopathic Urticaria, Perennial Allergy and treatment-resistant conditions.Condition
Clinical Trials
Trial Phases
Chronic Urticaria
1 Actively Recruiting
Phase 4
Perennial Allergy
0 Actively Recruiting
Not responsive to other therapy
0 Actively Recruiting
Perennial Allergic Rhinitis (PAR)
0 Actively Recruiting
Hay Fever
3 Actively Recruiting
Phase 3
Catarrh
2 Actively Recruiting
Phase 2, Not Applicable
Hay Fever
3 Actively Recruiting
Phase 1, Not Applicable, Phase 2
Seasonal Allergies
1 Actively Recruiting
Early Phase 1
Nasal Congestion
1 Actively Recruiting
Not Applicable
Xyzal Allergy 24Hr Reviews: What are patients saying about Xyzal Allergy 24Hr?
5Patient Review
12/19/2021 I tried the generic form of this medication, and it was completely ineffective. I could tell no difference whatsoever after taking it as directed. My husband then got me the name brand version, and within minutes I felt a world of difference. If you can afford it, always go for the name brand version!
5Patient Review
10/14/2022 I was having a lot of trouble with itchiness and feeling like something was crawling under my skin. My allergist put me on xyzal 10mg at night, and it's really helped clear up those issues. Plus, an added bonus is that my sinuses have dried up!
5Patient Review
12/19/2021 The generic brand of this medication did not work for me at all, but the name brand gave me relief within minutes. I will never go back to a cheaper option again.
5Patient Review
10/14/2022 I was having a lot of trouble with itching and feeling like something was crawling under my skin. My allergies were also acting up and I had occasional respiratory issues. My allergist put me on xyzal 10mg at night and it's helped clear everything up, plus an added bonus of drying up my sinuses.
4.3Patient Review
11/28/2020 I was completely satisfied with Xyzal until I started having nosebleeds. As that is a listed side effect, I stopped taking it immediately and the nosebleeds have since stopped.
4.3Patient Review
11/28/2020 After taking Xyzal for several weeks, I began having nosebleeds. I see that is listed as a serious side effect (especially for children), but I stopped it immediately. The nosebleeds have stopped as well. After having 3 bleeds within 24 hours, it got my attention.
4Patient Review
9/26/2021 While this medication is mild, I did find that it caused some light drowsiness and congestion relief. However, after a week of taking it I started to feel depressed and had nightmares. Given the light nature of this drug, the side effects are not worth it in my opinion.
4Patient Review
9/26/2021 I found this to be a mild antihistamine. It helped me sleep at night, but I didn't find it effective for severe allergy congestion. Additionally, I started feeling depressed after taking it for a week straight and had terrible nightmares. Given the light effect of the drug, it wasn't worth the side effects for me.
3.3Patient Review
10/14/2021 Allergy symptoms were much better, however I had trouble sleeping. Also frequently woke up to use the restroom and my urine was very dark in color. Overall, the benefits didn't outweigh the risks for me so I stopped taking this medication.
3.3Patient Review
10/14/2021 Helped with my allergies, but caused some serious sleeping issues like terrible nightmares and fatigue during the day. Also seemed to mess with my kidneys, as I was having dark urine and needing to urinate more frequently. Overall, the side effects were just too much for me to continue taking this medication.
3Patient Review
10/2/2020 I took this medication last night and felt no difference whatsoever compared to Benedryl. I was expecting more given the price tag, but sadly it did not meet my expectations.
3Patient Review
10/2/2020 I took this medication last night and I'm still feeling very tired today. It's basically the same as taking Benedryl, but much more expensive. I won't be using this again.
3Patient Review
6/11/2021 Though this treatment was alright, I found that it didn't last as long as advertised. I had to switch to Allegra, which worked better for me.
3Patient Review
6/11/2021 Though this treatment was effective, it didn't last the full 24 hours as advertised. I had to switch to Allegra, which worked better for me.
2.3Patient Review
9/26/2022 Did not help my allergies and made my nose stuffed at night making it harder to sleep. Did not make me drowsy. Pretty much worthless.
2.3Patient Review
5/17/2022 I was really hoping Xyzal would alleviate my allergies, but unfortunately the side effects were just too much to handle. It did dry up my sinuses, but also caused excruciating headaches and some muscle aches. I couldn't get out of bed the next day after using it three times in a row.
2.3Patient Review
9/26/2022 This did nothing to help my allergies and actually made it harder to sleep at night due to a stuffed nose. It also didn't make me drowsy, so I wouldn't recommend it for that purpose either.
2.3Patient Review
5/17/2022 I hoped Xyzal would help my allergies, but unfortunately the side effects were too severe. It did dry up my sinuses, but also caused terrible headaches and some muscle aches. I couldn't get out of bed the next day after using it three times.
1.7Patient Review
2/19/2021 The brain fog side effect is really terrible. I even experienced it the morning after taking the drug at night. In addition to that, I had a headache and my ears were ringing.
1.7Patient Review
2/19/2021 The brain fog side effect is really terrible. I even experienced it the morning after taking the medication at night. In addition to that, I had a headache and my ears were ringing.
1Patient Review
5/19/2022 I had a really terrible experience with this medication. After taking it for a month, I started having vertigo, pressure and pain in my ears, blurred vision, and tinnitus. I could barely stand because I was so dizzy. When I went to the ENT and eye doctor, they said everything was fine. But after looking up the side effects of the medicine, it fit perfectly. So I stopped taking it and finally a week later all my symptoms went away.
1Patient Review
4/10/2022 I took Claritin for a long time, but it eventually stopped working. I then tried another medication, but that didn't do anything at all.
1Patient Review
5/19/2022 After taking this medicine for a month, I started to experience intense vertigo, pressure and pain in my ears, blurred vision, and tinnitus. These symptoms were so severe that I thought I might have a brain tumor. Thankfully, after stopping the medication and waiting a week, all of my symptoms went away.
1Patient Review
4/10/2022 I took Claritin for a long time and it eventually stopped being effective. I then tried _____, but that didn't do anything at all.
Patient Q&A Section about xyzal allergy 24hr
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Are Xyzal and Zyrtec the same?
"The main difference between Xyzal and Zyrtec is that Xyzal pills are nearly half the size as Zyrtec pills. So, when looking for a smaller tablet, consider Xyzal."
Answered by AI
How many Xyzal can I take in 24 hours?
"Oral dosage form (Children's Xyzal® Allergy 24HR solution): Adults and children 12 years of age and over—Take 5 or 10 milliliters (mL) once a day in the evening. Don't take more than 10 mL in 24 hours."
Answered by AI
What happens if you take 2 Xyzal in 24 hours?
"If you take too much of the medication Xyzal, you should call your healthcare provider or local Poison Control Center, or seek emergency medical attention immediately. If a healthcare provider gives you Xyzal in a medical setting, it is unlikely that you will overdose on the medication."
Answered by AI
Does Xyzal allergy 24 hour make you drowsy?
"Xyzal may make you feel drowsy. In studies where people took it at night, 6% of them felt drowsy. You should take Xyzal at night and be careful if you're driving or operating machinery."
Answered by AI