Cutivate

Q: What is Cutivate used for?

<p>This medication can be used to treat <a href="https://www.withpower.com/clinical-trials/eczema">eczema</a>, <a href="https://www.withpower.com/clinical-trials/psoriasis">psoriasis</a>, and rash. It works by reducing swelling, itching, and redness. This is a medium-strength corticosteroid that is available as a cream, ointment, or lotion.</p>

House dust allergy, Sneezing, Allergic Rhinitis + 22 more

Treatment

20 Active Studies for Cutivate

Treatment for

House dust allergy

What is Cutivate

Fluticasone propionate

The Generic name of this drug

Treatment Summary

Fluticasone propionate is a steroid medication used to treat inflammation. It is available in the form of inhalers, nasal sprays, and topical creams. Fluticasone propionate was approved by the FDA in 1990 and has been used to treat a variety of inflammatory conditions since then.

Cutivate

is the brand name

image of different drug pills on a surface

Cutivate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cutivate

Fluticasone propionate

1990

366

Effectiveness

How Cutivate Affects Patients

When taken orally, fluticasone propionate reduces inflammation and eosinophilia in the lungs of rats. When applied topically, it has been shown to cause vasoconstriction (narrowing of blood vessels) on the skin.

How Cutivate works in the body

Fluticasone propionate helps reduce inflammation in the lungs by activating certain receptors and inhibiting eosinophilia in rats. We don't know exactly how it works, but it has been shown to be effective.

When to interrupt dosage

The proposed dosage of Cutivate is contingent upon the diagnosed condition, such as Sinusitis, Chronic Obstructive Pulmonary Disease (COPD) and Non-Allergic Rhinitis. The measure of dosage fluctuates as per the management approach (e.g. Spray, metered - Nasal or Respiratory (inhalation)) recorded in the table beneath.

Condition

Dosage

Administration

prophylaxis of Allergic rhinitis

, 0.05 mg, 0.0005 mg/mg, 0.00005 mg/mg, 0.25 mg, 0.1 mg, 0.5 mg, 0.044 mg, 0.11 mg, 0.22 mg, 0.5 mg/mL, 0.05 %, 0.045 mg, 0.115 mg, 0.23 mg, 0.055 mg, 0.113 mg, 0.232 mg, 0.093 mg, 5.0 mg/mg, 2.5 mg/mg, 0.1 mg/pump actuation, 0.055 mg/pump actuation, 0.25 mg/pump actuation, 0.5 mg/pump actuation, 0.125 mg/pump actuation, 0.05 mg/pump actuation, 0.113 mg/pump actuation, 0.025 mg/pump actuation, 0.232 mg/pump actuation, 0.202 mg

, Nasal, Spray, metered, Spray, metered - Nasal, Cream - Topical, Cream, Topical, Ointment, Ointment - Topical, Respiratory (inhalation), Powder, metered - Respiratory (inhalation), Powder, metered, Powder - Respiratory (inhalation), Powder, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Lotion - Topical, Lotion, Powder - Oral; Respiratory (inhalation), Oral; Respiratory (inhalation), Kit, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Kit - Topical, Spray, Spray - Nasal, Kit - Nasal

Bronchitis, Chronic

Eosinophilic Esophagitis

Allergy to Mold

Sinusitis

Nasal Congestion

Nose

Rhinitis

House dust allergy

Emphysema

Rhinorrhea

Hay Fever

Sinusitis

Adrenal Cortex Hormones

moderate, severe Seasonal Allergic Rhinitis

Asthma

Chronic Obstructive Pulmonary Disease

Allergy to Tree Pollen

Rhinitis, Allergic

Allergy to Animal Dander

Warnings

Cutivate has five contraindications and should not be combined with the ailments highlighted in the following table.

Cutivate Contraindications

Condition

Risk Level

Notes

Status Asthmaticus

Do Not Combine

Asthma

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Fluticasone Propionate may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Fluticasone Propionate may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Fluticasone Propionate may interact with Pulse Frequency

There are 20 known major drug interactions with Cutivate.

Common Cutivate Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Fluticasone propionate.

Abetimus

Major

The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Abetimus.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Fluticasone propionate.

Cutivate Toxicity & Overdose Risk

Not enough research has been done to know the effects of fluticasone propionate in certain groups. Studies on animals have shown that fluticasone propionate can cause birth defects if injected, but not if taken orally. There have not been any reported negative effects on pregnant women taking fluticasone propionate, but it is present in breast milk and may affect the growth of a baby. Children and elderly people taking fluticasone propionate may be more sensitive to its side effects. Fluticasone propionate affects people of all genders and races the same way. Those with liver issues should

image of a doctor in a lab doing drug, clinical research

Cutivate Novel Uses: Which Conditions Have a Clinical Trial Featuring Cutivate?

An extensive amount of investigations are actively assessing the potential of Cutivate to manage Nasal Congestion, House Dust Mite Allergy and Atopic Dermatitis.

Condition

Clinical Trials

Trial Phases

Bronchitis, Chronic

0 Actively Recruiting

Asthma

92 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3

Chronic Obstructive Pulmonary Disease

76 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4

Sinusitis

0 Actively Recruiting

Adrenal Cortex Hormones

0 Actively Recruiting

Emphysema

4 Actively Recruiting

Phase 2, Not Applicable

Sinusitis

6 Actively Recruiting

Early Phase 1, Phase 2, Phase 3, Phase 1

House dust allergy

0 Actively Recruiting

Rhinitis, Allergic

0 Actively Recruiting

Allergy to Mold

0 Actively Recruiting

Allergy to Tree Pollen

0 Actively Recruiting

Allergic Rhinitis

0 Actively Recruiting

Nose

0 Actively Recruiting

Eosinophilic Esophagitis

0 Actively Recruiting

moderate, severe Seasonal Allergic Rhinitis

0 Actively Recruiting

Sneezing

0 Actively Recruiting

Hay Fever

0 Actively Recruiting

House Dust Mite Allergy

0 Actively Recruiting

Non-Allergic Rhinitis

0 Actively Recruiting

Atopic Dermatitis

10 Actively Recruiting

Phase 2, Phase 3, Phase 4

Cutivate Reviews: What are patients saying about Cutivate?

Patient Review

8/14/2009

Cutivate for Scaly Oily Skin Problem Primarily On Face and Scalp

We used this on our 3-month-old daughter when we noticed a rash spreading from her face to her scalp and ears. We thought it might just be baby acne, but this cleared it up overnight! Now we just use it as needed for spot treatment.

Patient Review

4/13/2012

Cutivate for Atopic Dermatitis

This is a great medicine to have on hand for when my toddler gets hurt. It works quickly and really helps soothe her pain.

Patient Review

6/16/2008

Cutivate for Atopic Dermatitis

My son's eczema was really bad, but after using this treatment it completely cleared up.

Patient Review

10/3/2008

Cutivate for Rash

My son's rash was really bothering him, and it didn't seem to be going away no matter what we tried. But after using this treatment for just two days, the rash was completely gone!

Patient Review

1/23/2012

Cutivate for Atopic Dermatitis

Cutivate really helped me out when nothing else would. I have a persistent rash that comes and goes, but this ointment clears it up within a day or two every time.

4.7

Patient Review

1/22/2022

Cutivate for Atopic Dermatitis

I've used this treatment for about 5 years, usually just once or twice a month. I've never had any problems with it; it always works quickly and effectively overnight.

Patient Review

9/28/2008

Cutivate for Scaly Oily Skin Problem Primarily On Face and Scalp

I used this on my four-month-old's cradle cap and it cleared up within two applications.

Patient Review

11/10/2009

Cutivate for Psoriasis of Scalp

I used this medication for three months, as recommended. Unfortunately, I saw no improvement in my condition whatsoever. It was also very expensive; a 4 oz bottle cost me $344.

1.7

Patient Review

2/19/2009

Cutivate for Skin Rash that Becomes Thick & Discolored From Rubbing It

Not only was this medication ineffective, it was also very costly.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cutivate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What class steroid is Cutivate?

"Cutivate is a prescription medicine that is used to relieve the symptoms of Atopic dermatitis and Corticosteroid-responsive Dermatoses. Cutivate works by reducing inflammation, itchiness, and redness. It is typically used in conjunction with other medications. Cutivate is a type of corticosteroid drug, which is a class of drugs that are used to reduce inflammation."

Answered by AI

What is Cutivate ointment?

"Cutivate is a medicated lotion that's prescribed to relieve eczema symptoms such as itchy skin and inflammation (swelling). It's FDA-approved for use in adults and in children ages 3 months and older. Eczema, also called atopic dermatitis, is a common skin condition that causes itching, redness, and dryness."

Answered by AI

What is Cutivate used for?

"This medication can be used to treat eczema, psoriasis, and rash. It works by reducing swelling, itching, and redness. This is a medium-strength corticosteroid that is available as a cream, ointment, or lotion."

Answered by AI

Is Cutivate cream a steroid?

"Cutivate is a topical cream that contains the corticosteroid fluticasone propionate. It is used to treat skin conditions such as eczema, psoriasis, and allergic reactions. It works by reducing inflammation and itching."

Answered by AI

Clinical Trials for Cutivate

Have you considered Cutivate clinical trials?

We made a collection of clinical trials featuring Cutivate, we think they might fit your search criteria.

Image of Stanford University in Stanford, United States.

MoblO2 for Chronic Lung Diseases

18+

All Sexes

Stanford, CA

Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course. Practitioners prescribe O2 to patients with chronic lung disease in hopes of the following: 1) that it will limit desaturation events and combat breathlessness, thus preventing the frustratingly slow pace and numerous rest breaks patients are forced to adopt while doing even simple tasks; 2) that it will allow patients to be more active physically (perhaps increase their ability to exercise) and socially (perhaps leave the home more often); 3) that it will stave off putative complications of hypoxemia (e.g., cognitive dysfunction, pulmonary hypertension) and 4) that it will improve health-related quality of life (HRQL). However, despite the rationale for O2, and prescribers' good intentions, patients generally view O2 with frustration and fear - it threatens their HRQL, which is already impaired by having a condition that imposes itself on every aspect of their lives. Nasal cannulas and delivery devices call unwanted attention to patients when they are out in public. O2 users feel stigmatized and are often viewed as "smokers who get what they deserve, even if they never smoked a day in their lives" - or as disabled, sick or even infectious. O2 steals patients' independence, forcing them to plan their lives around it. The anxiety that patients and their caregivers experience around running out of oxygen, or not getting enough, immobilizes them and restricts participation in activities outside of the home. O2 disrupts the home environment, adding stress, and creating a burden for patients' caregiver-loved-ones who are often saddled with the responsibility of ensuring adequate equipment and supply of O2, and O2 is a constant reminder to patients they are living with a condition that could shorten their lives. O2 delivery equipment is typically heavy, unwieldy and intimidating. Different recommendations (e.g., insurance companies use 88% as a cut-off for SpO2, while many practitioners focus on 90%) make it confusing for patients, which almost certainly affects adherence. O2-requiringpatients are starving for things that can make their lives easier. An auto-adjusting O2 delivery device - one that automatically delivers the correct amount of O2 to maintain blood oxygen at desired, pre-set levels - would alleviate the need for patients to constantly (incessantly for many) monitor their peripheral oxygen saturation (SpO2) and adjust O2flow to meet the demands as exertion levels vary . The MoblO2 device is a battery-operated, light-weight, closed-loop O2 delivery device that houses a regulator (which attaches to compressed gas O2 tanks) and adjusts O2 flow to meet a pre-set blood oxygen level. A pulse oximeter is worn on the ear and transmits via Bluetooth to the device, which adjusts an internal valve to control flow on a second-to-second basis. The user sets the dial to the highest flow of O2 needed to meet the demands of activities they might perform (up to 15 liters per minute), and the device adjusts flow, up to the pre-set level to maintain SpO2 at a preset level (e.g., \> 90%). To conserve O2 supply in the tank - and to avoid over-oxygenation (which could be problematic for a small percentage of patients with the most severe COPD) - the MoblO2 begins to limit O2 flow at a SpO2 of 93%. The device can be manually over-ridden by the user, and should the battery run out - or the device fail for some unforeseen reason - the default position is valve open, so the users receive whatever flow of oxygen has been set on the dial. Given the substantial burdens of O2 on patients and their families, the hassles patients describe with having to monitor their SpO2 and repeatedly adjust the flow of O2 to meet their needs, patients and experts around the world have called for improvements in O2 delivery equipment. The MoblO2 is just such a remarkable improvement and a giant step forward in helping to ease the burdens of O2 on patients who require it. The purpose of this study is to investigate the effects of the MoblO2 O2 delivery device on a range of outcomes, including physical activity, amount (liters) O2 use; maintenance of adequate SpO2 levels; patient reported outcomes including symptoms, HRQL and satisfaction with the MoblO2 O2 device.

Waitlist Available

Has No Placebo

Stanford University

Jeff Swigris, DO, MS

Minnesota Health Solutions