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What is Chloramphenicol Sodium Succinate
Chloramphenicol succinateThe Generic name of this drug
Treatment SummaryChloramphenicol succinate is a medication derived from chloramphenicol, an antibiotic used to treat bacterial infections. Due to its potential to cause serious blood disorders, the use of Chloramphenicol succinate and Chloramphenicol has decreased. The FDA approved it in 1959.
Chloromycetin Sodium Succinateis the brand name
Chloramphenicol Sodium Succinate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Chloromycetin Sodium Succinate
Chloramphenicol succinate
1959
3
Effectiveness
How Chloramphenicol Sodium Succinate Affects PatientsChloramphenicol succinate is a drug that works by stopping bacteria from reproducing. It is a strong medication and should only be used under doctor's orders, as it can cause serious blood problems.
How Chloramphenicol Sodium Succinate works in the bodyChloramphenicol succinate is broken down into its active form. This active form mimics a molecule called uridine-5'-phosphate. It then binds to certain parts of bacterial cells, which stops them from making proteins. This stops the bacteria from growing and reproducing.
When to interrupt dosage
The recommended dosage of Chloramphenicol Sodium Succinate is contingent upon the established condition, such as Typhoid Fever, Cystic Fibrosis (CF) and Bacterial Infections. The quantity of dosage varies, as per the procedure of delivery (e.g. Powder, for solution or Intravenous) specified in the table below.Condition
Dosage
Administration
Communicable Diseases
, 100.0 mg/mL, 1000.0 mg
, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Intravenous, Injection, Injection - Intravenous, Powder, for solution - Intravenous, Powder, for solution
Disease
, 100.0 mg/mL, 1000.0 mg
, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Intravenous, Injection, Injection - Intravenous, Powder, for solution - Intravenous, Powder, for solution
Bacterial Infections
, 100.0 mg/mL, 1000.0 mg
, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Intravenous, Injection, Injection - Intravenous, Powder, for solution - Intravenous, Powder, for solution
Cystic Fibrosis (CF)
, 100.0 mg/mL, 1000.0 mg
, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, lyophilized, for solution, Intravenous, Injection, Injection - Intravenous, Powder, for solution - Intravenous, Powder, for solution
Warnings
Chloramphenicol Sodium Succinate has two contraindications. It should not be consumed while undergoing any of the conditions detailed in the following table.Chloramphenicol Sodium Succinate ContraindicationsCondition
Risk Level
Notes
Communicable Diseases
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Chloramphenicol Succinate may interact with Pulse Frequency
Common Chloramphenicol Sodium Succinate Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Chloramphenicol succinate.
Typhoid vaccine
Minor
The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Chloramphenicol succinate.
(R)-warfarin
Moderate
The risk or severity of bleeding can be increased when Chloramphenicol succinate is combined with (R)-warfarin.
(S)-Warfarin
Moderate
The risk or severity of bleeding can be increased when Chloramphenicol succinate is combined with (S)-Warfarin.
4-hydroxycoumarin
Moderate
The risk or severity of bleeding can be increased when Chloramphenicol succinate is combined with 4-hydroxycoumarin.
Chloramphenicol Sodium Succinate Toxicity & Overdose RiskSigns of an overdose include shock, bluish skin, and unconsciousness. Treatment for an overdose on this drug may involve providing fluids, exchanging blood transfusions, and administering dopamine.
Chloramphenicol Sodium Succinate Novel Uses: Which Conditions Have a Clinical Trial Featuring Chloramphenicol Sodium Succinate?
Two active trials are assessing the potential of Chloramphenicol Sodium Succinate to combat Bacterial Infections, Communicable Diseases and Typhoid Fever.Condition
Clinical Trials
Trial Phases
Bacterial Infections
0 Actively Recruiting
Disease
0 Actively Recruiting
Cystic Fibrosis (CF)
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Chloramphenicol Sodium Succinate Reviews: What are patients saying about Chloramphenicol Sodium Succinate?
5Patient Review
11/9/20123.7Patient Review
4/17/2017 I was born with a staff infection and this drug was the only thing that worked.
Patient Q&A Section about chloramphenicol sodium succinate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the most toxic reaction to chloramphenicol?
"Chloramphenicol can lead to two very serious, but rare, toxic effects. These are "gray syndrome" and bone marrow aplasia. Gray syndrome is a condition where newborns have a vasomotor collapse, caused by too high of a dose of chloramphenicol given through injection. Bone marrow aplasia is when the bone marrow is unable to produce blood cells. Both of these conditions have a high mortality rate."
Answered by AI
What was chloramphenicol used for?
"Chloramphenicol is used to treat serious infections in different parts of the body. It is sometimes given with other antibiotics. However, chloramphenicol should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections."
Answered by AI
What type of drug is chloramphenicol?
"Chloramphenicol is a medication used to treat superficial eye infections, such as bacterial conjunctivitis, and otitis externa. It is an antibiotic that inhibits protein synthesis."
Answered by AI
What is the other name for chloramphenicol?
"Chloramphenicol is used to treat serious infections including typhoid fever, Rocky Mountain spotted fever, rickettsial infections, meningitis, plague and bronchitis. Chloramphenicol was first introduced in the 1950s.
Chloramphenicol is a man-made antibiotic that is used to treat serious infections including typhoid fever, Rocky Mountain spotted fever, rickettsial infections, meningitis, plague and bronchitis. Chloramphenicol was first introduced in the 1950s."
Answered by AI