Captopril And Hydrochlorothiazide

Ventricular Dysfunction, Left, Hyperaldosteronism, Renal Artery Stenosis + 9 more

Treatment

10 FDA approvals

20 Active Studies for Captopril And Hydrochlorothiazide

Treatment for

Ventricular Dysfunction, Left

What is Captopril And Hydrochlorothiazide

CaptoprilThe Generic name of this drug

Treatment SummaryCaptopril is a medication used to treat high blood pressure. It works by blocking the enzyme that converts angiotensin I, a hormone that helps regulate blood pressure, into angiotensin II. By stopping this conversion, Captopril helps to lower blood pressure levels.

Capotenis the brand name

image of different drug pills on a surface

Captopril And Hydrochlorothiazide Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Capoten

Captopril

1981

183

Approved as Treatment by the FDA

Captopril, otherwise known as Capoten, is approved by the FDA for 10 uses like Ventricular Dysfunction, Left and Type 1 Diabetes Mellitus .

Ventricular Dysfunction, Left

Helps manage ejection fraction of 40% or less Left ventricular dysfunction

Type 1 Diabetes Mellitus

Helps manage Type 1 Diabetes Mellitus

ejection fraction of 40% or less Left ventricular dysfunction

Helps manage ejection fraction of 40% or less Left ventricular dysfunction

Diabetic Nephropathy

Helps manage Diabetic Nephropathy

Hypertensive disease

Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide

Congestive Heart Failure (CHF)

Helps manage Congestive Heart Failure (CHF)

Type 1 Diabetes

Helps manage Type 1 Diabetes Mellitus

Heart Attack

Helps manage Myocardial Infarction

Congestive Heart Failure

Helps manage Congestive Heart Failure (CHF)

Diabetic Nephropathies

Helps manage Diabetic Nephropathy

Effectiveness

How Captopril And Hydrochlorothiazide Affects PatientsCaptopril, an ACE inhibitor, works by blocking the action of a hormone system (RAAS) that controls blood pressure and water balance. When there is stress or reduced blood pressure in the kidneys, this system (renin-angiotensin-aldosterone system) releases a hormone (renin) that changes into another hormone (angiotensin I) which then changes into yet another hormone (angiotensin II). This hormone (angiotensin II) raises blood pressure in three ways: it encourages the body to absorb more salt and water, it releases another hormone (vasopressin) that also

How Captopril And Hydrochlorothiazide works in the bodyThere are two forms of ACE: one found in the body and one found in the testicles. The body form is made of two parts that work together to control blood pressure. ACE inhibitors target both parts, but have a stronger effect on the part that affects blood pressure. Captopril is an ACE inhibitor that stops the body from breaking down a molecule called ATI. This lowers the amount of a second molecule (ATII) in the body, which also helps reduce blood pressure. Captopril also increases the activity of a molecule called renin, which helps regulate blood pressure. Captopril is very good at binding to ACE,

When to interrupt dosage

The advisable dosage of Captopril And Hydrochlorothiazide is contingent upon the recognized condition, such as Heart Attack, Non-STEMI Acute Coronary Syndrome and Aldosteronism. The measure of dosage modifies as per the technique of delivery (e.g. Oral or Tablet - Oral) highlighted in the table beneath.

Condition

Dosage

Administration

Ventricular Dysfunction, Left