Treatment for Opioid Withdrawal (Disorder)

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Johns Hopkins University Bayview Medical Campus, Baltimore, MD
Opioid Withdrawal (Disorder)+4 More
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether there are differences in the expression of opioid withdrawal symptoms in people with opioid use disorder while they are completing a clinically-indicated medication taper.

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Eligible Conditions

  • Opioid Withdrawal (Disorder)
  • Opioid Use Disorder (OUD)
  • Opioid Craving

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 2 primary outcomes in patients with Opioid Withdrawal (Disorder). Measurement will happen over the course of Days 1 through 5.

Days 1 through 5
Withdrawal severity during naloxone challenge
Days 6 through 10
Withdrawal severity during lofexidine taper

Trial Safety

Safety Estimate

2 of 3
This is better than 68% of similar trials

Trial Design

0 Treatment Group

This trial requires 60 total participants across 0 different treatment group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: days 6 through 10
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly days 6 through 10 for reporting.

Closest Location

Johns Hopkins University Bayview Medical Campus - Baltimore, MD

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
A urine sample that contains opioids. show original
is a required inclusion criterion for opioid maintenance treatment with buprenorphine/naloxone in the United States show original
The 18 year old is young, and the 65 year old is old. show original
Interest in undergoing opioid taper

Patient Q&A Section

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Other questions from users

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any geographic restrictions to consider when applying for this trial?

Patients from any state can participate in this trial, so long as they are able to attend all treatment sessions.

Will my insurance cover participating in this trial?

In order to understand how insurance coverage works for this trial, you will need to contact the study coordinator.

See if you qualify for this trial
Get access to this novel treatment for Opioid Withdrawal (Disorder) by sharing your contact details with the study coordinator.