Comprehensive Behavioral Intervention for Tics (CBIT) for Tic Disorders

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Miami, Coral Gables, FL
Tic Disorders
Comprehensive Behavioral Intervention for Tics (CBIT) - Behavioral
Eligibility
< 18
All Sexes
What conditions do you have?
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Study Summary

The purpose of this protocol is to examine treatment outcomes of youth receiving the Comprehensive Behavioral Intervention for Tics (CBIT) and better understand the predictors, moderators, mediators and/or mechanisms of change for this intervention.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Tic Disorders

Study Objectives

10 Primary · 2 Secondary · Reporting Duration: Change from baseline YQOL Scores, to 6 weeks, to 12 weeks from the start of treatment.

Week 12
Yale Global Tic Severity Scale (YGTSS) - Overall Tic Related Impairment Scores
Week 12
Clinical Global Impression (CGI) - Improvement Scores
Week 12
Clinical Global Impression (CGI) - Severity Scale Scores
Week 12
Premonitory Urge Tic Scale (PUTS)
Week 12
Revised Children's Anxiety and Depression Scale - Child and Revised Parent Short (RCADS-25/RCADS-P-25) Scores
Week 12
Tic Accommodation and Reactions Scale (TARS) Scores
Week 12
Youth Quality of Life (YQOL) Instrument - Short Form (SF) Scores
Week 12
Parent Tic Questionnaire (PTQ)
Week 12
Yale Global Tic Severity Scale (YGTSS) - Global Severity Score
Week 12
Yale Global Tic Severity Scale (YGTSS) - Total Motor Tic Scores
Week 12
Yale Global Tic Severity Scale (YGTSS) - Total Phonic Tic Score
Week 12
Yale Global Tic Severity Scale (YGTSS) - Total Tic Scores

Trial Safety

Safety Progress

1 of 3

Other trials for Tic Disorders

Trial Design

1 Treatment Group

Comprehensive Behavioral Intervention for Tics (CBIT)
1 of 1
Experimental Treatment

200 Total Participants · 1 Treatment Group

Primary Treatment: Comprehensive Behavioral Intervention for Tics (CBIT) · No Placebo Group · N/A

Comprehensive Behavioral Intervention for Tics (CBIT)
Behavioral
Experimental Group · 1 Intervention: Comprehensive Behavioral Intervention for Tics (CBIT) · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Comprehensive Behavioral Intervention for Tics (CBIT)
2012
Completed Phase 1
~90

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: change from baseline yqol scores, to 6 weeks, to 12 weeks from the start of treatment.
Closest Location: University of Miami · Coral Gables, FL
Photo of University of Miami 1Photo of University of Miami 2Photo of University of Miami 3
1991First Recorded Clinical Trial
1 TrialsResearching Tic Disorders
621 CompletedClinical Trials

Who is running the clinical trial?

University of MiamiLead Sponsor
780 Previous Clinical Trials
381,562 Total Patients Enrolled
Jill Ehrenreich-May, Ph.D.Study DirectorUniversity of Miami
2 Previous Clinical Trials
276 Total Patients Enrolled

Eligibility Criteria

Age < 18 · All Participants · 3 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.