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Behavioral Intervention

Rumination-Focused Cognitive Behavioral Therapy for Depression (RFCBT-I Trial)

N/A

Recruiting

Led By Patrick Possel, Dr.rer.soc.

Research Sponsored by University of Louisville

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 33 weeks after baseline 1

Awards & highlights

RFCBT-I Trial Summary

This trial will explore if treating depression can reduce risk of heart disease in low-income Americans. #HeartDisease #Depression #RFCBT

Who is the study for?

This trial is for individuals who often have negative thoughts that loop continuously (rumination), are experiencing mild to moderate depression, and have high blood pressure. Participants must score at least 11 on the RSQ-Brooding scale, between 10-20 on the PHQ-9 depression scale, and have a systolic blood pressure of 120 or higher or diastolic blood pressure of 80 or higher. They also need to be fluent in English.Check my eligibility

What is being tested?

The study is testing Rumination-Focused Cognitive Behavioral Therapy (RFCBT) to see if it can reduce the risk of heart disease by targeting rumination—a factor linked to both depression and heart health—especially in low-income patients.See study design

What are the potential side effects?

Since RFCBT is a type of talk therapy focused on changing thought patterns, there are no direct physical side effects like with medication. However, discussing negative thoughts may initially cause discomfort or emotional distress.

RFCBT-I Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 33 weeks after baseline 1

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~33 weeks after baseline 1

This trial's timeline: 3 weeks for screening, Varies for treatment, and 33 weeks after baseline 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Patient Health Questionnaire-9

Response Style Questionnaire

diastolic blood pressure measures

+1 more

RFCBT-I Trial Design

1Treatment groups

Experimental Treatment

Group I: RFCBTExperimental Treatment1 Intervention

This is a single subject design study. Thus, all participants receive Rumination-Focused Cognitive Behavior Therapy

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Rumination-Focused Cognitive Behavior Therapy

2013

N/A

~40

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of LouisvilleLead Sponsor

339 Previous Clinical Trials

76,671 Total Patients Enrolled

Patrick Possel, Dr.rer.soc.Principal InvestigatorUniversity of Louisville

1 Previous Clinical Trials

740 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the research team currently seeking new participants?

"According to clinicaltrials.gov, this trial is presently enlisting participants. It was initially announced on August 15th 2023 and subsequently modified on October 16th of the same year."

Answered by AI

To what extent is the research sample size in this investigation?

"Yes, according to clinicaltrials.gov the trial is recruiting participants and it was initially posted on August 15th 2023 with a recent update occurring October 16th of the same year. Nine individuals are needed at one particular site for this medical research endeavour."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease?

Patrick Possel 2023. "Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease?". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05980130.

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