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Water Dosing for Orthostatic Hypotension

N/A

Waitlist Available

Led By Satish R Raj, MD MSCI

Research Sponsored by Satish R. Raj

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 18-80 years

Orthostatic hypotension (fall in BP>20/10 mmHg)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2nd intervention

Awards & highlights

Study Summary

This trial is testing whether drinking water will help blood pressure in patients with low blood pressure when standing up, when they have had a lot to drink beforehand.

Who is the study for?

This trial is for adults aged 18-80 with orthostatic hypotension, which means their blood pressure drops significantly when standing up. They should have previously shown a blood pressure increase after drinking water in other studies. Pregnant individuals cannot participate.Check my eligibility

What is being tested?

The study investigates the effect of two different doses of water on blood pressure in patients with orthostatic hypotension. It aims to determine if the pressor (blood-pressure raising) response to water diminishes when a full dose is taken earlier.See study design

What are the potential side effects?

Drinking high or low doses of water typically does not cause side effects; however, it may lead to discomfort from bloating or stomach fullness and very rarely might contribute to changes in electrolyte balance.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 18 and 80 years old.

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My blood pressure drops significantly when I stand up.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2nd intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2nd intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2nd intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

blood pressure

Secondary outcome measures

heart rate

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: 1Experimental Treatment1 Intervention

16 oz water in AM

Group II: 2Active Control1 Intervention

water 1 oz in AM

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Satish R. RajLead Sponsor

6 Previous Clinical Trials

510 Total Patients Enrolled

1 Trials studying Orthostatic Hypotension

20 Patients Enrolled for Orthostatic Hypotension

Satish R Raj, MD MSCIPrincipal InvestigatorVanderbilt University Medical Center

19 Previous Clinical Trials

1,406 Total Patients Enrolled

2 Trials studying Orthostatic Hypotension

20 Patients Enrolled for Orthostatic Hypotension

Media Library

water high dose Clinical Trial Eligibility Overview. Trial Name: NCT00580996 — N/A

Orthostatic Hypotension Research Study Groups: 1, 2

Orthostatic Hypotension Clinical Trial 2023: water high dose Highlights & Side Effects. Trial Name: NCT00580996 — N/A

water high dose 2023 Treatment Timeline for Medical Study. Trial Name: NCT00580996 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What criteria must potential participants fulfill to qualify for this research endeavor?

"This medical experiment is actively searching for 20 individuals between 18 and 80 years of age who suffer from orthostatic hypotension. Furthermore, candidates must have shown a pressor response to water in past studies."

Answered by AI

Does this research initiative allow for participation from those over the age of forty?

"This trial mandates that all participants be 18 years of age or older, with no upper limit for eligibility; the maximum permitted age is 80."

Answered by AI

Is there still the opportunity to join this experiment?

"According to clinicaltrials.gov, this experiment is not accepting new participants at present. The trial was initially uploaded on July 1st 2006 and last updated September 12th 2022; however, there are 110 other studies currently recruiting patients."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Water and the Gastropressor Response - Tachyphylaxis

Satish R. Raj 2006. "Water and the Gastropressor Response - Tachyphylaxis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00580996.

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