Your session is about to expire
← Back to Search
Psilocybin-assisted Psychotherapy for Opioid Use Disorder
Study Summary
This trial tests if a type of psychedelic therapy can help people reduce their opioid use for chronic pain. Participation lasts 8 months and includes two 25mg psilocybin therapy sessions. Outcomes will be tracked for safety & effectiveness.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2021 Phase 2 trial • 95 Patients • NCT02061293Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I have a serious sleep disorder like sleep apnea that's not being treated.I can swallow pills.I have been on a stable opioid dose for at least 90 days.I've tried and failed to stop taking opioids before but want to try again.My chronic pain is caused by my cancer.I am not pregnant, planning to become pregnant, or breastfeeding during the study.I have not taken any mood stabilizers, antidepressants, or similar drugs in the last 8 weeks.I have been diagnosed with a psychotic disorder, such as schizophrenia, major depression with psychosis, or bipolar disorder.I have been on a stable dose of opioid pain medication for at least 90 days.I have a long-term pain condition like nerve pain or chronic back pain.You have a very serious problem with alcohol or drugs, as defined by the DSM-5. This does not include an opioid use disorder.You are unable to stay away from nicotine for 6-8 hours during the study.You have used drugs like LSD, MDMA, or ketamine in the past year.You have a history of a developmental disorder.You have serious health conditions that may or may not affect your mental well-being, as determined by the study doctor.I have asthma.I am between 19 and 75 years old.I've tried and failed to stop or reduce my long-term opioid use but want to try again.I have had a stroke or a mini-stroke (TIA) in the past.My liver is not working well.You have been diagnosed with antisocial or borderline personality disorders according to the DSM-5.I have a long-term pain condition like nerve pain, fibromyalgia, chronic headaches, back pain, or muscle pain.I have a close family member with schizophrenia or bipolar disorder.I can swallow pills.I am between 19 and 75 years old.I have epilepsy.I have a serious heart condition or abnormal heart test results.I require insulin to manage my diabetes.
- Group 1: Psilocybin-assisted Psychotherapy
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does the upper age limit for this clinical trial include seniors?
"People aged 19 to 75 who meet the other inclusion criteria are eligible for this clinical trial. There are 592 trials for people over 65 and 51 trials for people under 18."
Are there any opportunities for people to participate in this trial?
"This particular trial, which was posted on December 15th, 2022 and last updated October 14th, is no longer recruiting patients. However, there are 690 other active clinical trials that may be of interest."
Who would be an eligible candidate for this research?
"In order to be selected for this experiment, hopefuls must suffer from chronic pain and fall between the ages of 19-75. Unfortunately, only 10 people will be able to participate."
When will Psilocybin-assisted Psychotherapy be available to the general public?
"While there is some clinical evidence supporting the safety of Psilocybin-assisted Psychotherapy, it remains unproven whether or not the intervention is effective. Consequently, it received a score of 2."
Who else is applying?
What state do they live in?
How old are they?
What portion of applicants met pre-screening criteria?
What site did they apply to?
How many prior treatments have patients received?
Why did patients apply to this trial?
What questions have other patients asked about this trial?
How responsive is this trial?
Typically responds via
Most responsive sites:
- University of British Columbia - Okanagan Campus: < 48 hours
Average response time
- < 2 Days
Share this study with friends
Copy Link
Messenger