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Diagnostic Imaging

MRI Screening for Prostate Cancer

N/A
Recruiting
Led By Danny J Vesprini, MD, MSc, FRCPC
Research Sponsored by Toronto Sunnybrook Regional Cancer Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be 50 years of age or older
Have positive genetic testing for a pathogenic BRCA1 or BRCA2 mutation
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years january 2016
Awards & highlights

Study Summary

This trial is testing whether MRI can help detect prostate cancer earlier in men who are at high risk for the disease because they have a BRCA1 or BRCA2 mutation.

Who is the study for?
This trial is for men over 50 who are part of the Male Hereditary Cancer Research Program, have a BRCA1 or BRCA2 mutation, and can undergo an ultrasound biopsy. It's not for those with claustrophobia, MRI contraindications, contrast agent issues, or previous prostate cancer diagnosis.Check my eligibility
What is being tested?
The study tests if using MRI as a screening tool helps detect prostate cancer earlier in men at high risk due to BRCA mutations. This is compared to standard PSA testing and digital rectal examination.See study design
What are the potential side effects?
Potential side effects may include discomfort from the MRI procedure or reactions to the contrast agent used during imaging. The biopsy could cause pain, bleeding, infection risks or urinary problems.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 50 years old or older.
Select...
I have a positive test for a harmful BRCA1 or BRCA2 mutation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years (january 2016)
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years (january 2016) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Prostate MRI in BRCA carriers
Secondary outcome measures
Prostate cancer in BRCA carriers

Trial Design

1Treatment groups
Experimental Treatment
Group I: MS3TMRI / TRUS Guided BiopsyExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Women's College HospitalOTHER
99 Previous Clinical Trials
38,711 Total Patients Enrolled
Toronto Sunnybrook Regional Cancer CentreLead Sponsor
9 Previous Clinical Trials
893 Total Patients Enrolled
2 Trials studying Prostate Cancer
146 Patients Enrolled for Prostate Cancer
Sunnybrook Health Sciences CentreOTHER
654 Previous Clinical Trials
1,543,257 Total Patients Enrolled
33 Trials studying Prostate Cancer
12,202 Patients Enrolled for Prostate Cancer

Media Library

MS3TMRI (Diagnostic Imaging) Clinical Trial Eligibility Overview. Trial Name: NCT01990521 — N/A
Prostate Cancer Research Study Groups: MS3TMRI / TRUS Guided Biopsy
Prostate Cancer Clinical Trial 2023: MS3TMRI Highlights & Side Effects. Trial Name: NCT01990521 — N/A
MS3TMRI (Diagnostic Imaging) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01990521 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the estimated size of this medical experiment's participant pool?

"Affirmative, the information available on clinicaltrials.gov implies that recruitment for this experiment is ongoing. Initially posted in January 2014, it was subsequently edited as recently as May 2022 and seeks a total of 60 individuals from 1 test site."

Answered by AI

Can participants join this experiment currently?

"According to the clinicaltrials.gov registry, this medical study is currently seeking participants. It was initially made available on January 1st 2014 and recently revised on May 5th 2022."

Answered by AI
~4 spots leftby Dec 2024