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Diagnostic Imaging
MRI Screening for Prostate Cancer
N/A
Recruiting
Led By Danny J Vesprini, MD, MSc, FRCPC
Research Sponsored by Toronto Sunnybrook Regional Cancer Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be 50 years of age or older
Have positive genetic testing for a pathogenic BRCA1 or BRCA2 mutation
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years january 2016
Awards & highlights
Study Summary
This trial is testing whether MRI can help detect prostate cancer earlier in men who are at high risk for the disease because they have a BRCA1 or BRCA2 mutation.
Who is the study for?
This trial is for men over 50 who are part of the Male Hereditary Cancer Research Program, have a BRCA1 or BRCA2 mutation, and can undergo an ultrasound biopsy. It's not for those with claustrophobia, MRI contraindications, contrast agent issues, or previous prostate cancer diagnosis.Check my eligibility
What is being tested?
The study tests if using MRI as a screening tool helps detect prostate cancer earlier in men at high risk due to BRCA mutations. This is compared to standard PSA testing and digital rectal examination.See study design
What are the potential side effects?
Potential side effects may include discomfort from the MRI procedure or reactions to the contrast agent used during imaging. The biopsy could cause pain, bleeding, infection risks or urinary problems.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 50 years old or older.
Select...
I have a positive test for a harmful BRCA1 or BRCA2 mutation.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 years (january 2016)
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years (january 2016)
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Prostate MRI in BRCA carriers
Secondary outcome measures
Prostate cancer in BRCA carriers
Trial Design
1Treatment groups
Experimental Treatment
Group I: MS3TMRI / TRUS Guided BiopsyExperimental Treatment1 Intervention
Find a Location
Who is running the clinical trial?
Women's College HospitalOTHER
99 Previous Clinical Trials
38,711 Total Patients Enrolled
Toronto Sunnybrook Regional Cancer CentreLead Sponsor
9 Previous Clinical Trials
893 Total Patients Enrolled
2 Trials studying Prostate Cancer
146 Patients Enrolled for Prostate Cancer
Sunnybrook Health Sciences CentreOTHER
654 Previous Clinical Trials
1,543,257 Total Patients Enrolled
33 Trials studying Prostate Cancer
12,202 Patients Enrolled for Prostate Cancer
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am 50 years old or older.I cannot have MRI contrast due to a medical reason.I have been diagnosed with prostate cancer before.I am willing and able to have an ultrasound biopsy within 4 weeks after my MRI.I have a positive test for a harmful BRCA1 or BRCA2 mutation.
Research Study Groups:
This trial has the following groups:- Group 1: MS3TMRI / TRUS Guided Biopsy
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is the estimated size of this medical experiment's participant pool?
"Affirmative, the information available on clinicaltrials.gov implies that recruitment for this experiment is ongoing. Initially posted in January 2014, it was subsequently edited as recently as May 2022 and seeks a total of 60 individuals from 1 test site."
Answered by AI
Can participants join this experiment currently?
"According to the clinicaltrials.gov registry, this medical study is currently seeking participants. It was initially made available on January 1st 2014 and recently revised on May 5th 2022."
Answered by AI
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