Dr. Danny Vesprini, MD
Claim this profileSunnybrook Odette Cancer Centre
Studies Prostate Cancer
Studies Prostate Adenocarcinoma
6 reported clinical trials
7 drugs studied
Area of expertise
1Prostate Cancer
BRCA1 positive
BRCA2 positive
Stage III
2Prostate Adenocarcinoma
Affiliated Hospitals
Clinical Trials Danny Vesprini, MD is currently running
Rectal Hydrogel Spacer
for Prostate Cancer
There are several single institutional series that have reported their experience with salvage radiotherapy options that include EBRT, LDR and HDR brachytherapy. Gastrointestinal (GI) toxicity with salvage radiotherapy range between14-58%, respectively for patients undergoing re-irradiation. There is a concern for an increased risk of fistula development in these patients who receive second course of radiation. Hypofractionation using SABR has been utilized in the re-irradiation setting for prostate cancer with good tumor control and toxicity outcomes. In order to decrease the rectal toxicity, dose to the rectum should be kept as low as possible. Several techniques can be used to achieve this: tighter dosimetric dose painting, better patient or organ immobilization or use of a biodegradable gel. The Investigators ropose a phase I study to assess placement of a hydrogel spacer between the prostate and rectum, in an effort to decrease toxicity and improve patient's bowel quality of life.
Recruiting1 award N/A
Targeted Radiotherapy
for Prostate Cancer
This study is a single centre feasibility trial. The trial will recruit men with intermediate risk localised prostate cancer who will all receive targeted dose (escalated/de-escalated dose directed by MRI) 5 fraction SBRT to the prostate. Trial Objectives are: 1. Primary To develop a 5 fraction de-escalated dose SBRT protocol capable of reducing side effects 2. Secondary * To assess levels of acute GU and GI toxicity (CTCAE) * To assess levels of late GU and GI toxicity (CTCAE) * To assess late sexual quality of life (expanded EPIC, IIEF-5) * To assess biochemical relapse-free survival at 2
Recruiting1 award N/A10 criteria
More about Danny Vesprini, MD
Clinical Trial Related7 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Danny Vesprini, MD has experience with
- Stereotactic Ablative Body Radiation
- MR Linac Delivered Radiotherapy
- SBRT
- MS3TMRI
- TRUS Guided Biopsy
- SABR
Breakdown of trials Danny Vesprini, MD has run
Prostate Cancer
Prostate Adenocarcinoma
Breast Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Danny Vesprini, MD specialize in?
Danny Vesprini, MD focuses on Prostate Cancer and Prostate Adenocarcinoma. In particular, much of their work with Prostate Cancer has involved BRCA1 positive patients, or patients who are BRCA2 positive.
Is Danny Vesprini, MD currently recruiting for clinical trials?
Yes, Danny Vesprini, MD is currently recruiting for 3 clinical trials in Toronto Ontario. If you're interested in participating, you should apply.
Are there any treatments that Danny Vesprini, MD has studied deeply?
Yes, Danny Vesprini, MD has studied treatments such as Stereotactic Ablative Body Radiation, MR Linac delivered Radiotherapy, SBRT.
What is the best way to schedule an appointment with Danny Vesprini, MD?
Apply for one of the trials that Danny Vesprini, MD is conducting.
What is the office address of Danny Vesprini, MD?
The office of Danny Vesprini, MD is located at: Sunnybrook Odette Cancer Centre, Toronto, Ontario M4N 3M5 Canada. This is the address for their practice at the Sunnybrook Odette Cancer Centre.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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