← Back to Search

Radiation Therapy

SBRT for Breast Cancer

N/A
Recruiting
Led By Danny Vesprini, MD, FRCPC
Research Sponsored by Toronto Sunnybrook Regional Cancer Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years post treatment
Awards & highlights

Study Summary

This trial will study if SBRT is an effective treatment for 24 patients with unresectable breast cancer.

Eligible Conditions
  • Breast Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years post treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years post treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Acute toxicity
Secondary outcome measures
Breast Symptom Scores
Patient Reported Pain Level
Patient Reported Quality of Life
+1 more

Side effects data

From 2024 Phase 2 trial • 57 Patients • NCT03004183
21%
Fatigue
13%
Nausea
11%
Back pain
9%
Shortness of Breath
9%
Anemia
9%
Abdominal pain
9%
Diarrhea
7%
Kidney Injury and/or Infection
7%
Pneumonia
7%
Dyspnea
7%
Weight Loss
5%
Malnutrition, Hypercalcemia and Weakness
5%
Pneumothorax
5%
Activated partial thromboplastin time prolonged
5%
Intractable pain, back pain, hip pain
4%
Pleural effusion
4%
Atrial fibrillation with rapid ventricular response
2%
Skin rash
2%
Thrombocytopenia
2%
Respiratory failure
2%
colitis
100%
80%
60%
40%
20%
0%
Study treatment Arm
Single Arm

Trial Design

1Treatment groups
Experimental Treatment
Group I: SBRT to the Primary Breast TumourExperimental Treatment1 Intervention
SBRT to the breast using 4 sequentially escalating dose levels from 9Gy to 12 Gy.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
SBRT
2014
Completed Phase 2
~1060

Find a Location

Who is running the clinical trial?

Toronto Sunnybrook Regional Cancer CentreLead Sponsor
9 Previous Clinical Trials
929 Total Patients Enrolled
1 Trials studying Breast Cancer
30 Patients Enrolled for Breast Cancer
Danny Vesprini, MD, FRCPCPrincipal InvestigatorSunnybrook Health Sciences Centre, University of Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities for prospective participants to join this research endeavor?

"Affirmative. Clinicaltrials.gov records indicate that this medical trial is actively seeking participants, with the first posting on July 17th 2018 and an update dated to May 5th 2022. 24 individuals are being sought from one research centre for recruitment into the study."

Answered by AI

How many participants are being recruited for this research endeavor?

"Affirmative. Clinicaltrials.gov indicates that this research study is recruiting patients, which began on July 17th 2018 and was last updated on May 5th 2022. 24 participants are being sought from one clinical centre."

Answered by AI
~4 spots leftby Mar 2025