XEN1101 for Epilepsy
(X-TOLE4 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial will test the safety and effectiveness of taking a 25 mg pill of XEN1101 in patients with specific types of seizures. The goal is to see if it can help control their seizures by affecting brain activity. Participants must have completed earlier related studies.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the study team or your doctor.
Who Is on the Research Team?
Medical Director
Principal Investigator
Xenon Pharmaceuticals Inc.
Are You a Good Fit for This Trial?
This trial is for individuals with Focal Onset Seizures or Primary Generalized Tonic-Clonic Seizures who have completed a previous study without early termination or significant issues. Participants must be able to follow the study's instructions, keep accurate seizure diaries, and provide informed consent.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive XEN1101 for the treatment of seizures, with visits at 2-, 4-, and 13-weeks post-entry, and subsequent visits at 13-week intervals during the first year, then at 26-week intervals with a telephone call in between
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- XEN1101
Find a Clinic Near You
Who Is Running the Clinical Trial?
Xenon Pharmaceuticals Inc.
Lead Sponsor
Worldwide Clinical Trials
Collaborator