Briviact

Seizures

Treatment

4 Active Studies for Briviact

Treatment for

Seizures

What is Briviact

Brivaracetam

The Generic name of this drug

Treatment Summary

Brivaracetam is a medication used to treat partial-onset seizures. It is derived from levetiracetam and binds to the protein SV2A with 20 times more strength. It is available under the brand name Briviact and was approved by the FDA in 2016.

Briviact

is the brand name

image of different drug pills on a surface

Briviact Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Briviact

Brivaracetam

2016

Effectiveness

How Briviact Affects Patients

Brivaracetam binds strongly to a protein (SV2A) that plays a role in the development of epilepsy by affecting the release of GABA. It is thought that this binding is how brivaracetam helps to prevent epilepsy. Additionally, brivaracetam is thought to also prevent epilepsy by blocking certain sodium channels in the body.

How Briviact works in the body

We don't know exactly how brivaracetam prevents seizures.

When to interrupt dosage

The recommended measure of Briviact is contingent upon the identified condition. The quantity of dosage deviates as per the administration strategy specified in the table below.

Condition

Dosage

Administration

Seizures

, 25.0 mg, 75.0 mg, 100.0 mg, 10.0 mg, 50.0 mg, 10.0 mg/mL, 50.0 mg/mL

Tablet - Oral, Oral, Tablet, , Intravenous, Solution - Intravenous, Solution, Solution - Oral, Tablet, film coated, Tablet, film coated - Oral, Injection, solution, Injection, solution - Intravenous, Injection, suspension - Intravenous, Injection, suspension

Warnings

There are 20 known major drug interactions with Briviact.

Common Briviact Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Cyclophosphamide

Major

The metabolism of Cyclophosphamide can be decreased when combined with Brivaracetam.

Dosulepin

Major

The metabolism of Dosulepin can be decreased when combined with Brivaracetam.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Brivaracetam.

Ethanol

Major

Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Briviact Toxicity & Overdose Risk

Taking too much of this drug can cause sleepiness and unsteadiness. No evidence that it increases the risk of cancer or affects fertility.

image of a doctor in a lab doing drug, clinical research

Briviact Novel Uses: Which Conditions Have a Clinical Trial Featuring Briviact?

Two current clinical trials are examining the potential of Briviact to alleviate Seizures.

Condition

Clinical Trials

Trial Phases

Seizures

5 Actively Recruiting

Phase 3, Phase 2, Phase 1

Briviact Reviews: What are patients saying about Briviact?

Patient Review

12/5/2016

Briviact for Additional Medication to Treat Partial Seizures

I have epilepsy and switched from Keppra to Breviact. I noticed less side effects with this new medication, such as bleeding gums, dry nasal passages and mouth, anxiety, and stuffiness.

Patient Review

1/28/2019

Briviact for Simple Seizure

This medication has been effective for me at treating seizures (have not had any since starting on it), but I have had rough side effects: depression, blurry vision, losing my train of thought mid sentence, mood swings throughout the day, and irritability. I switched to it after having similar side effects while on Keppra, but Keppra wasn't as bad. I am now switching to Lamotrigine hoping that will help.

2.7

Patient Review

10/23/2017

Briviact for Additional Medication to Treat Partial Seizures

Though this treatment is more convenient in that I only have to take two pills per day, it unfortunately has not been as effective at preventing seizures as the Keppra XR brand.

Patient Review

8/16/2020

Briviact for Simple Seizure

I've only been on this for three days and I'm already struggling. The ringing in my ears is so loud that it drowns out every other noise, and it's giving me a headache. I can't stand any more noise.

Patient Review

12/20/2016

Briviact for Additional Medication to Treat Partial Seizures

I tried this treatment once before in a trial study at UCSF, and I had visual hallucinations as a result. It's only become legal recently, so I decided to give it another shot; unfortunately, the hallucinations were just as bad as before.

Patient Review

11/12/2017

Briviact for Additional Medication to Treat Partial Seizures

I tried this medication for two weeks, and it made me so incredibly dizzy, nauseated, and uncoordinated that I could barely function. I had to stop taking it.

Patient Review

8/1/2022

Briviact for Additional Medication to Treat Partial Seizures

I sleep for 12 hours per day and I am still severely depressed. This medication may help reduce seizures, but it doesn't improve the quality of my life at all. I'm just a shell of my former self.

Patient Review

12/11/2017

Briviact for Additional Medication to Treat Partial Seizures

This medication was completely ineffective and, unfortunately, made my seizures worse. I had some of the worst seizures of my life while taking this drug. It should not have been approved for use.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about briviact

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Briviact prescribed for?

"BRIVIACT is a prescription medicine used to treat partial-onset seizures in children 1 month of age or older. Ask your doctor if BRIVIACT might be right for your child."

Answered by AI

Is Briviact the same as Keppra?

"Briviact and Keppra are both anticonvulsant medications that target the synaptic vesicle protein 2A (SV2A) in the brain. Briviact is a newer medication and is more selective for this receptor than Keppra, meaning that it has a higher affinity for the receptor."

Answered by AI