Briviact

Seizures
Treatment
2 Active Studies for Briviact

What is Briviact

BrivaracetamThe Generic name of this drug
Treatment SummaryBrivaracetam is a medication used to treat partial-onset seizures. It is derived from levetiracetam and binds to the protein SV2A with 20 times more strength. It is available under the brand name Briviact and was approved by the FDA in 2016.
Briviactis the brand name
image of different drug pills on a surface
Briviact Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Briviact
Brivaracetam
2016
7

Effectiveness

How Briviact Affects PatientsBrivaracetam binds strongly to a protein (SV2A) that plays a role in the development of epilepsy by affecting the release of GABA. It is thought that this binding is how brivaracetam helps to prevent epilepsy. Additionally, brivaracetam is thought to also prevent epilepsy by blocking certain sodium channels in the body.
How Briviact works in the bodyWe don't know exactly how brivaracetam prevents seizures.

When to interrupt dosage

The recommended measure of Briviact is contingent upon the identified condition. The quantity of dosage deviates as per the administration strategy specified in the table below.
Condition
Dosage
Administration
Seizures
, 25.0 mg, 75.0 mg, 100.0 mg, 10.0 mg, 50.0 mg, 10.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Solution - Oral, Solution, Solution - Intravenous, Intravenous, Tablet, film coated, Tablet, film coated - Oral, Injection, solution, Injection, solution - Intravenous, Injection, suspension, Injection, suspension - Intravenous

Warnings

There are 20 known major drug interactions with Briviact.
Common Briviact Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Brivaracetam.
Dosulepin
Major
The metabolism of Dosulepin can be decreased when combined with Brivaracetam.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Brivaracetam.
Ethanol
Major
Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Briviact Toxicity & Overdose RiskTaking too much of this drug can cause sleepiness and unsteadiness. No evidence that it increases the risk of cancer or affects fertility.
image of a doctor in a lab doing drug, clinical research

Briviact Novel Uses: Which Conditions Have a Clinical Trial Featuring Briviact?

Two current clinical trials are examining the potential of Briviact to alleviate Seizures.
Condition
Clinical Trials
Trial Phases
Seizures
2 Actively Recruiting
Phase 3

Briviact Reviews: What are patients saying about Briviact?

5Patient Review
12/5/2016
Briviact for Additional Medication to Treat Partial Seizures
I have epilepsy and switched from Keppra to Breviact. I noticed less side effects with this new medication, such as bleeding gums, dry nasal passages and mouth, anxiety, and stuffiness.
4Patient Review
1/28/2019
Briviact for Simple Seizure
This medication has been effective for me at treating seizures (have not had any since starting on it), but I have had rough side effects: depression, blurry vision, losing my train of thought mid sentence, mood swings throughout the day, and irritability. I switched to it after having similar side effects while on Keppra, but Keppra wasn't as bad. I am now switching to Lamotrigine hoping that will help.
2.7Patient Review
10/23/2017
Briviact for Additional Medication to Treat Partial Seizures
Though this treatment is more convenient in that I only have to take two pills per day, it unfortunately has not been as effective at preventing seizures as the Keppra XR brand.
2Patient Review
8/16/2020
Briviact for Simple Seizure
I've only been on this for three days and I'm already struggling. The ringing in my ears is so loud that it drowns out every other noise, and it's giving me a headache. I can't stand any more noise.
1Patient Review
12/20/2016
Briviact for Additional Medication to Treat Partial Seizures
I tried this treatment once before in a trial study at UCSF, and I had visual hallucinations as a result. It's only become legal recently, so I decided to give it another shot; unfortunately, the hallucinations were just as bad as before.
1Patient Review
11/12/2017
Briviact for Additional Medication to Treat Partial Seizures
I tried this medication for two weeks, and it made me so incredibly dizzy, nauseated, and uncoordinated that I could barely function. I had to stop taking it.
1Patient Review
8/1/2022
Briviact for Additional Medication to Treat Partial Seizures
I sleep for 12 hours per day and I am still severely depressed. This medication may help reduce seizures, but it doesn't improve the quality of my life at all. I'm just a shell of my former self.
1Patient Review
12/11/2017
Briviact for Additional Medication to Treat Partial Seizures
This medication was completely ineffective and, unfortunately, made my seizures worse. I had some of the worst seizures of my life while taking this drug. It should not have been approved for use.
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Patient Q&A Section about briviact

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Briviact prescribed for?

"BRIVIACT is a prescription medicine used to treat partial-onset seizures in children 1 month of age or older. Ask your doctor if BRIVIACT might be right for your child."

Answered by AI

Is Briviact the same as Keppra?

"Briviact and Keppra are both anticonvulsant medications that target the synaptic vesicle protein 2A (SV2A) in the brain. Briviact is a newer medication and is more selective for this receptor than Keppra, meaning that it has a higher affinity for the receptor."

Answered by AI

What type of seizures does Briviact treat?

"Briviact is a drug used to treat partial seizures in people with epilepsy. It is for use in adults and children who are at least one month old."

Answered by AI

What are the side effects for Briviact?

"Symptoms of concussion can include: feeling sleepy, dizzy, or tired; feeling nauseous or vomiting; and having problems with balance."

Answered by AI

Clinical Trials for Briviact