Axid

Pemphigus, Macular Edema, Iridocyclitis + 102 more

Treatment

57 FDA approvals

20 Active Studies for Axid

Treatment for

Pemphigus

What is Axid

DexamethasoneThe Generic name of this drug

Treatment SummaryHydrocodone is a synthetic painkiller derived from codeine. It is usually used in combination with acetaminophen to manage moderate to severe pain. In the past, hydrocodone was also used as a cough suppressant, but this has been largely replaced with dextromethorphan in cough and cold medications. A more powerful form of this drug called hydromorphone is used for treating severe pain. The FDA approved Hydrocodone for use in the cough suppressant syrup Hycodan in 1943.

Decadronis the brand name

image of different drug pills on a surface

Axid Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Decadron

Dexamethasone

1958

452

Approved as Treatment by the FDA

Dexamethasone, also known as Decadron, is approved by the FDA for 57 uses which include Mycosis Fungoides (MF) and Epicondylitis .

Mycosis Fungoides (MF)

Helps manage Mycosis Fungoides (MF)

Epicondylitis

Helps manage Epicondylitis

Rosacea

Helps manage Rosacea

Hypercalcemia

Helps manage Hypercalcemia

Brain

Helps manage Edema of the cerebrum

Perennial Allergic Rhinitis (PAR)

Helps manage Perennial Allergic Rhinitis (PAR)

Adrenal cortical hypofunctions

Helps manage Adrenal cortical hypofunctions

Malignant Lymphomas

Helps manage Malignant Lymphomas

Loeffler's syndrome

Helps manage Loeffler's syndrome

Ankylosing Spondylitis

Helps manage Ankylosing Spondylitis (AS)

Synovitis

Helps manage Synovitis

exfoliative erythroderma

Helps manage exfoliative erythroderma

Optic Neuritis

Helps manage Optic Neuritis

Congenital adrenal hyperplasia

Helps manage Congenital Adrenal Hyperplasia (CAH)

anterior eye segment inflammation

Helps manage anterior eye segment inflammation

Lupus

Helps manage Systemic Lupus Erythematosus (SLE)

acquired immune hemolytic anemia

Helps manage acquired immune hemolytic anemia

Crohn Disease

Helps manage Regional Enteritis

Bursitis

Helps manage Bursitis

Allergic Conjunctivitis (AC)

Helps manage Allergic Conjunctivitis (AC)

Congenital Hypoplastic Anemia

Helps manage Congenital Hypoplastic Anemia

Rheumatoid Arthritis, Juvenile

Helps manage Rheumatoid Arthritis, Juvenile

Acute Myeloid Leukemia (AML)

Helps manage Acute Leukemia (Category)

Tuberculosis (TB)

Helps manage Tuberculosis (TB)

Trialled at least two prior therapies including lenalidomide and a proteasome inhibitor

Used to treat Trialled at least two prior therapies including lenalidomide and a proteasome inhibitor in combination with Isatuximab

Drug Allergy

Helps manage Drug hypersensitivity reaction

Stevens-Johnson Syndrome

Helps manage Stevens-Johnson Syndrome

Berylliosis

Helps manage Berylliosis

Bullous dermatitis herpetiformis

Helps manage Bullous dermatitis herpetiformis

Pemphigus

Helps manage Pemphigus

Ophthalmia, Sympathetic

Helps manage Ophthalmia, Sympathetic

Psoriasis

Helps manage severe Psoriasis

Ulcerative Colitis

Helps manage Ulcerative Colitis

Inflammation

Hay Fever

Helps manage Seasonal Allergic Rhinitis

Cushing's Syndrome

Asthma

Helps manage Asthma

Trichinosis

Helps manage Trichinosis

Iritis

Helps manage Iritis

Degenerative polyarthritis

Helps manage Posttraumatic Osteoarthritis

Iridocyclitis

Helps manage Iridocyclitis

Rheumatoid Arthritis

Helps manage Rheumatoid Arthritis

Acute Coryza

Helps manage acute rheumatic carditis

Choroiditis

Helps manage Choroiditis

varicella-zoster virus acute retinal necrosis

Helps manage varicella-zoster virus acute retinal necrosis

Arthritis, Gouty

Helps manage Acute Gouty Arthritis

Chorioretinitis

Helps manage Chorioretinitis

Erythroblastopenia

Helps manage Erythroblastopenia

Multiple Myeloma

Used to treat Multiple Myeloma (MM) in combination with Isatuximab

Adrenocortical Hyperfunction

Seborrheic dermatitis

Helps manage Severe Seborrheic Dermatitis

Serum Sickness

Helps manage Serum Sickness

Secondary thrombocytopenia

Helps manage Secondary thrombocytopenia

Sarcoidosis

Helps manage Sarcoidosis

Uveitis

Helps manage Uveitis

Thyroiditis

Helps manage non-suppurative Thyroiditis

Aspiration Pneumonitis

Helps manage Aspiration Pneumonitis

Effectiveness

How Axid Affects PatientsHydrocodone is a painkiller that works by blocking pain signals in the brain and spine. It can also create feelings of euphoria, make it harder to breathe, and make people feel sleepy.

How Axid works in the bodyHydrocodone binds to two types of opioid receptors, the mu and delta receptors. It is the mu receptor that is primarily responsible for its pain-relieving effects. Hydrocodone works by preventing neurons from sending signals to the brain that cause pain. It also inhibits neurons that would normally be activated by glutamate. In addition, it can activate neurons in the brain responsible for pleasure and reward, which can lead to addiction. Hydrocodone can also depress breathing, cause sedation, and suppress the cough reflex. Delta receptors may also contribute to hydrocodone's pain-relieving effects, but this has not been

When to interrupt dosage

The suggested dosage of Axid is contingent upon the diagnosed condition, including Coughing, Coughing and Chronic Pain. The measure additionally wavers as indicated by the means of delivery (e.g. Tablet, extended release - Oral or Tablet - Oral) outlined in the table underneath.

Condition

Dosage

Administration

Tuberculosis (TB)

, 0.7 mg, 0.001 mg/mg, 10.0 mg/mL, 4.0 mg/mL, 1.5 mg, 1.0 mg/mL, 4.0 mg, 0.75 mg, 1.0 mg, 2.0 mg, 6.0 mg, 0.5 mg, 0.5 mg/mL, 0.1 %, 40.0 mg, 0.0005 mg/mg, 517.0 mg/mL, 0.0015 mg/mg, 0.4 mg, 20.0 mg, 0.1 mg/mL, 0.5 mg/units

, Implant, Implant - Intravitreal, Intravitreal, Ointment, Ointment - Ophthalmic, Ophthalmic, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Injection, solution - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Oral, Tablet, Tablet - Oral, Solution / drops - Ophthalmic, Solution / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Suspension, Suspension / drops, Solution, Solution - Ophthalmic, Auricular (otic), Suspension - Auricular (otic), Intramuscular, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Injection, Intra-articular; Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Elixir, Elixir - Oral, Liquid, Liquid - Intramuscular; Intravenous, Intramuscular; Intrasynovial; Intravenous, Liquid - Intramuscular; Intrasynovial; Intravenous, Liquid - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Auricular (otic); Ophthalmic, Solution / drops - Auricular (otic); Ophthalmic, Solution - Intramuscular; Intrasynovial; Intravenous, Solution - Auricular (otic); Ophthalmic, Solution - Intra-articular; Intramuscular; Intravenous, Topical, Solution / drops - Topical, Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ointment - Topical, Liquid - Auricular (otic); Ophthalmic, Ointment - Auricular (otic); Ophthalmic, Solution - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Solution - Intramuscular; Intravenous, Liquid - Intra-articular; Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Oral, Suspension / drops - Auricular (otic), Injection - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Dental, Liquid - Dental, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Injection - Intramuscular, Solution - Parenteral, Parenteral, Injection, solution - Ophthalmic, Intraocular, Injection, solution - Intraocular, Injection, suspension, Injection, suspension - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue, Intramuscular; Intravenous; Topical, Kit - Intramuscular; Intravenous; Topical, Injection, emulsion, Injection, emulsion - Intramuscular; Intravenous, Insert, Insert - Ophthalmic, Solution - Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Perineural; Topical, Epidural; Infiltration; Intramuscular; Intravenous; Perineural; Topical, Perineural, Suspension / drops - Topical

Iridocyclitis

Chorioretinitis

Stevens-Johnson Syndrome

Iritis

Hypercalcemia

Loeffler's syndrome

Erythroblastopenia

Bullous dermatitis herpetiformis

exfoliative erythroderma

Drug Allergy

Adrenal cortical hypofunctions

Hay Fever

Ocular Inflammation

Asthma

Lupus Erythematosus, Discoid

Lichen Planus (LP)

Mycosis Fungoides (MF)

Perennial Allergic Rhinitis (PAR)

Ocular Inflammation and Pain

Warnings

Axid has twenty-one contraindications, and it ought not to be taken when having any of the conditions presented in the following table.Axid Contraindications

Condition

Risk Level

Notes

active periocular infections

Do Not Combine

Eye

Do Not Combine

Tympanic membrane structure

Do Not Combine

suspected periocular infections

Do Not Combine

Eye Infections, Fungal

Do Not Combine

Viral Conjunctivitis

Do Not Combine

Communicable Diseases

Do Not Combine

Eye Infection

Do Not Combine

Mycoses

Do Not Combine

acute infectious stages of varicella

Do Not Combine

External auditory canal structure

Do Not Combine

epithelial herpes simplex keratitis

Do Not Combine

External Ear

Do Not Combine

torn posterior lens

Do Not Combine

Open-angle glaucoma

Do Not Combine

Cornea

Do Not Combine

active ocular infections

Do Not Combine

ruptured posterior lens

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Dexamethasone may interact with Pulse Frequency

There are 20 known major drug interactions with Axid.

Common Axid Drug Interactions

Drug Name

Risk Level

Description

1,2-Benzodiazepine

Major

The metabolism of 1,2-Benzodiazepine can be increased when combined with Dexamethasone.

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Dexamethasone is combined with 2-Methoxyethanol.

3,5-diiodothyropropionic acid

Major

The metabolism of 3,5-diiodothyropropionic acid can be increased when combined with Dexamethasone.

6-O-benzylguanine

Major

The metabolism of 6-O-benzylguanine can be increased when combined with Dexamethasone.

7-ethyl-10-hydroxycamptothecin

Major

The metabolism of 7-ethyl-10-hydroxycamptothecin can be increased when combined with Dexamethasone.

Axid Toxicity & Overdose RiskTaking too much hydrocodone can cause symptoms such as shallow breathing, sleepiness, and muscle weakness. If this happens, it is important to make sure the person has a clear airway and that they are receiving enough oxygen. Other treatments like IV fluids, oxygen, and medicines to raise blood pressure may be needed. In some cases, a medicine called naloxone may be used to reverse the effects of the overdose. Even after taking naloxone, people should continue to be monitored in case the effects of the overdose come back. Naloxone can also cause withdrawal symptoms if given to someone who is used to

image of a doctor in a lab doing drug, clinical research

Axid Novel Uses: Which Conditions Have a Clinical Trial Featuring Axid?

A total of 50 active trials are assessing the ability of Axid to alleviate Chronic Pain, Nasal Congestion caused by Common Cold and Acute Bronchitis.

Condition

Clinical Trials

Trial Phases

Chorioretinitis

0 Actively Recruiting

anterior eye segment inflammation

0 Actively Recruiting

Necrobiosis lipoidica diabeticorum

0 Actively Recruiting

Psoriasis

0 Actively Recruiting

Granuloma Annulare

0 Actively Recruiting

Trichinosis

0 Actively Recruiting

ear infection-not otherwise specified caused by susceptible bacteria

0 Actively Recruiting

Pemphigus

1 Actively Recruiting

Phase 1

Keloids Scars

1 Actively Recruiting

Not Applicable

Middle ear inflammation

0 Actively Recruiting

Bullous dermatitis herpetiformis

0 Actively Recruiting

Bursitis

6 Actively Recruiting

Phase 4, Not Applicable

Asthma

160 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1, Phase 3

Bacterial Infections

0 Actively Recruiting

Acute Otitis Media (AOM)

3 Actively Recruiting

Not Applicable

Thyroiditis

0 Actively Recruiting

Ophthalmia, Sympathetic

0 Actively Recruiting

Otitis Externa

0 Actively Recruiting

Phlyctenular keratoconjunctivitis

0 Actively Recruiting

Iridocyclitis

1 Actively Recruiting

Phase 2, Phase 3

Axid Reviews: What are patients saying about Axid?

5Patient Review

3/3/2011

Axid for Condition in which Stomach Acid is Pushed Into the Esophagus

This product offers rapid relief from stomach discomfort caused by onions, peppers, and heartburn.

5Patient Review

3/25/2010

Axid for Inflammation of the Esophagus with Erosion

This drug helped me with my sudden stomach problems and I also lost the desire to drink alcohol, which is a good thing. I recommend this over Prilosic

5Patient Review

6/17/2009

Axid for Conditions of Excess Stomach Acid Secretion

The only side effect I experienced was very bad constipation.

5Patient Review

4/9/2013

Axid for Condition in which Stomach Acid is Pushed Into the Esophagus

I've been using Axid for a long time and it's really helped me with heartburn, acid indigestion, and burning throat. I'm finding it hard to locate now. What's up with this??? IT'S WONDERFUL!!! Please tell me where to get it now that Wal-Mart doesn't carry it any longer.

5Patient Review

10/5/2020

Axid for Inflammation of Esophagus from Backflow of Stomach Acid

I don't know why this medication is no longer available, because it worked great for me for 30 years. I hope it becomes available again soon.

5Patient Review

3/23/2009

Axid for Inflammation of Esophagus from Backflow of Stomach Acid

I've had stomach problems for a while now, and this is the only treatment that has worked for me. My doctor prescribed it to me, and it seems to be doing its job; I had a test done on my stomach that showed the ulcers were healing within a week of starting to take the medicine. I'm really grateful for this medication because it's helping me get rid of my stomach pains and other issues.

4.7Patient Review

9/25/2008

Axid for Stomach Ulcer

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about axid

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Axid still sold?

"TheAxid brand will no longer be sold in the U.S. If the FDA has approved generic versions of this product, there may be generic equivalents available."

Answered by AI

What are the side effects of Axid?

"The text lists various symptoms which may include a headache, dizziness, rash, diarrhea, a runny or stuffy nose, a sore throat, or a cough."

Answered by AI

What is the generic name for Axid?

"This medication is used to treat ulcers in the stomach and intestines and to prevent them from returning after they have healed. It is also used to treat certain stomach and throat problems such as erosive esophagitis and gastroesophageal reflux disease."

Answered by AI

How often can you take Axid?

"The recommended oral dosage of Axid is 300 mg given either as 150 mg twice daily or 300 mg once daily at bedtime. Prior to treatment, care should be taken to exclude the possibility of malignant gastric ulceration."

Answered by AI