Hypofractionated radiation therapy for Mucosal Melanoma of the Head and Neck
Study Summary
This trial is testing a new cancer treatment combining hypofractionated radiotherapy (HRT) with pembrolizumab. The goal is to see if this new treatment is more effective than HRT alone in controlling the tumor. Safety will also be monitored.
- Mucosal Melanoma of the Head and Neck
Treatment Effectiveness
Study Objectives
1 Primary · 5 Secondary · Reporting Duration: 1 year
Trial Safety
Safety Progress
Side Effects for
Trial Design
1 Treatment Group
Pembrolizumab + Hypofractionated radiation therapy
1 of 1
Experimental Treatment
16 Total Participants · 1 Treatment Group
Primary Treatment: Hypofractionated radiation therapy · No Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age Any Age · All Participants · 6 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Are there long-term repercussions to Hypofractionated radiation therapy?
"While Phase 2 trials don't have data supporting efficacy, there is some evidence indicating that hypofractionated radiation therapy is safe." - Anonymous Online Contributor
How many volunteers are participating in this research project?
"That is correct. The trial, which began recruiting on May 29th 2020 and was last updated February 7th 2022, is looking for 16 patients from a single location." - Anonymous Online Contributor
What cancerous tumors does Hypofractionated radiation therapy usually target?
"Hypofractionated radiation therapy can be used to target and treat malignant neoplasms, unresectable melanoma, and microsatellite instability high." - Anonymous Online Contributor
Can new patients still sign up to participate in this research?
"The clinical trial is still recruiting patients, as seen on the website clinicaltrials.gov. The listing for this study was first posted on May 29th, 2020 and updated February 7th, 2022." - Anonymous Online Contributor
Are there any precedent studies that have used Hypofractionated radiation therapy?
"Right now, there are 1000 ongoing clinical trials for Hypofractionated radiation therapy. 122 of these studies are in Phase 3. The majority of these Houston-based trials originated in Texas but there are 36053 locations running similar studies." - Anonymous Online Contributor