Ansaid

Pain, Chronic Pain, Postoperative Pain + 14 more

Treatment

5 FDA approvals

20 Active Studies for Ansaid

What is Ansaid

Flurbiprofen

The Generic name of this drug

Treatment Summary

Flurbiprofen is a type of medication used to reduce inflammation, fever, and pain. It is taken orally to treat rheumatoid arthritis, osteoarthritis and anklylosing spondylitis, or applied topically to the eyes prior to surgery. Flurbiprofen is similar to other drugs like ibuprofen, fenoprofen, and ketoprofen in terms of structure and effect.

Ocufen

is the brand name

Ansaid Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Ocufen

Flurbiprofen

1987

34

Approved as Treatment by the FDA

Flurbiprofen, also called Ocufen, is approved by the FDA for 5 uses including Menstrual Distress (Dysmenorrhea) and Ankylosing Spondylitis (AS) .

Menstrual Distress (Dysmenorrhea)

Ankylosing Spondylitis (AS)

Ankylosing Spondylitis

Pain

Dysmenorrhea

Effectiveness

How Ansaid Affects Patients

Flurbiprofen is a type of nonsteroidal anti-inflammatory drug (NSAID) similar to fenoprofen, ibuprofen, and ketoprofen. It works to reduce inflammation, pain, and fever. This drug is composed of two different forms (left and right-hand versions) known as enantiomers. The left-hand version is believed to be the one that provides most of the anti-inflammatory effects, while both versions may help with pain relief.

How Ansaid works in the body

Flurbiprofen is a type of non-steroidal anti-inflammatory drug (NSAIA) which works by blocking an enzyme that turns fatty acids into molecules that cause inflammation. This stops the production of these inflammatory molecules and helps to reduce pain, swelling and fever. Flurbiprofen is especially powerful at blocking this enzyme, making it one of the most effective NSAIAs.

When to interrupt dosage

The measure of Ansaid is reliant upon the distinguished ailment, including Postoperative Pain, Menstrual Distress (Dysmenorrhea) and Back. The total of dosage varies, contingent upon the technique of delivery (e.g. Tablet, film coated or Liquid - Ophthalmic) specified in the table underneath.

Condition

Dosage

Administration

Pain

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Chronic Pain

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Postoperative Pain

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Rheumatoid Arthritis

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Rheumatoid Arthritis

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Pain

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Neurodegenerative Diseases

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Dysmenorrhea

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Back

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Spasm

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Lumbar Region

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Osteoarthritis

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Ankylosing Spondylitis

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Epilepsy, Post-Traumatic

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Chronic Back Pain

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Wounds and Injuries

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Spasm

0.3 mg/mL, , 100.0 mg, 0.242 mg/mL, 3.3 mg, 50.0 mg, 200.0 mg, 0.03 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Topical, Topical, Tablet, Tablet - Oral, Capsule, extended release - Oral, Capsule, extended release, Liquid, Liquid - Ophthalmic

Warnings

There are 20 known major drug interactions with Ansaid.

Common Ansaid Drug Interactions

Drug Name

Risk Level

Description

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Flurbiprofen.

Belinostat

Major

The metabolism of Belinostat can be decreased when combined with Flurbiprofen.

Binimetinib

Major

The metabolism of Binimetinib can be decreased when combined with Flurbiprofen.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Flurbiprofen.

Etoposide

Major

The metabolism of Etoposide can be decreased when combined with Flurbiprofen.

Ansaid Toxicity & Overdose Risk

The toxic dose of flurbiprofen in dogs is 10mg/kg when taken orally. It has been linked to an increased risk of heart attack, stroke, high blood pressure, fluid retention and swelling, and stomach irritation. It can also cause kidney damage, allergic reactions, abdominal pain, constipation, diarrhea, indigestion, gas, vomiting, anemia, dizziness, headache, prolonged bleeding, itching, rashes, and ringing in the ears. Rarely, allergic reactions may occur.

Ansaid Novel Uses: Which Conditions Have a Clinical Trial Featuring Ansaid?

293 active studies are being conducted to assess the potential of Ansaid to alleviate symptoms associated with Osteoarthritis (OA), Rheumatoid Arthritis and Pain.

Condition

Clinical Trials

Trial Phases

Chronic Pain

130 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1, Phase 1

Spasm

0 Actively Recruiting

Rheumatoid Arthritis

8 Actively Recruiting

Not Applicable, Phase 4, Phase 2

Back

0 Actively Recruiting

Postoperative Pain

19 Actively Recruiting

Phase 4, Phase 2, Phase 1, Phase 3, Not Applicable

Pain

0 Actively Recruiting

Neurodegenerative Diseases

4 Actively Recruiting

Phase 2, Phase 3, Not Applicable

Dysmenorrhea

1 Actively Recruiting

Not Applicable

Spasm

0 Actively Recruiting

Pain

0 Actively Recruiting

Wounds and Injuries

7 Actively Recruiting

Not Applicable, Phase 3

Ankylosing Spondylitis

3 Actively Recruiting

Phase 3, Not Applicable

Chronic Back Pain

5 Actively Recruiting

Not Applicable

Lumbar Region

1 Actively Recruiting

Not Applicable

Epilepsy, Post-Traumatic

0 Actively Recruiting

Rheumatoid Arthritis

55 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Osteoarthritis

0 Actively Recruiting

Ansaid Reviews: What are patients saying about Ansaid?

5

Patient Review

3/3/2010

Ansaid for Joint Damage causing Pain and Loss of Function

I have osteoarthritis in my knee, which was exacerbated by spinal fusion surgery. I tried this medication in conjunction with Synevisc and after taking it for a few months, I feel much better. I would recommend this to others who are struggling with similar issues.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about ansaid

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Ansaid good for toothache?

"It is used to relieve pain in conditions like headache, mild migraines, muscle pain, joint pain, tooth pain, menstrual pain, ankylosing spondylitis, osteoarthritis and rheumatoid arthritis."

Answered by AI

What is Ancid used for?

"Ancid 150mg Tablet is a medicine that reduces the amount of acid your stomach makes. It can be used to treat and prevent heartburn as well as indigestion and other symptoms caused by too much acid in the stomach. It can also be used to treat and prevent stomach ulcers, reflux disease, and some rarer conditions."

Answered by AI

What is Ansaid tablets used for?

"Ansaid is a prescription medicine used to treat the symptoms of Rheumatoid arthritis and Osteoarthritis. Ansaid may be used alone or with other medications."

Answered by AI

Is Ansaid the same as ibuprofen?

"Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. Flurbiprofen is similar to other NSAIDs such as ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others."

Answered by AI

Clinical Trials for Ansaid

Image of University Center for Ambulatory Surgery in Somerset, United States.

Infusion Pump for Postoperative Pain

18+
All Sexes
Somerset, NJ

This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period.. Patients 18 years or older undergoing ACL reconstruction, open shoulder labrum or rotator cuff surgery, arthroscopic rotator cuff repair, proximal or distal patellar realignment surgery, open knee arthrotomy cases (i.e. inside out meniscus repair, osteochondral allograft transplantation (OCA), meniscal allograft transplantation (MAT)) at University Center for Ambulatory Surgery, LLC (UOA) will be reviewed for eligibility. Once identified, potential study subjects will be asked whether they are interested in participating in the project. If the patient agrees, the subject will be given the informed consent to read and sign. Objectives: The primary objective is to compare the effectiveness of postoperative infusion pain pump versus preoperative nerve block in reducing visual analog pain scores/numerical pain rating scale (VAS/NPRS) in the postoperative period. The second objective is to evaluate the requirement of narcotic and non-narcotic analgesic medications between the two groups. Hypotheses: Use of continuous infusion pain pump or single shot peripheral block will result in similar post-operative pain control after outpatient sports medicine surgical cases.

Phase 4
Recruiting

University Center for Ambulatory Surgery

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

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Image of St. John's Rehab at Sunnybrook in Toronto, Canada.

Peer Support Program for Traumatic Injury

18+
All Sexes
Toronto, Canada

Traumatic injuries from events like car crashes, falls, or fires are a leading cause of disability. Survivors often face not only physical challenges but also long-lasting pain, mental health challenges and difficulty returning to work and family life. Although medical care focuses on physical recovery, survivors frequently report that their emotional and social needs are overlooked and unmet. Peer support-guidance from people who have lived through similar injuries-can reduce distress and improve coping. However, no programs in Canada currently provide peer support to trauma survivors across their recovery journey, from hospital to rehabilitation to community living. The investigators worked with trauma survivors, caregivers, and healthcare providers to co-design a Peer Support Program (PSP) that offers support throughout these stages. This pilot study will test whether the program is feasible and acceptable, and explore its early impact on recovery. Results will guide a future larger trial to expand peer support in trauma care.

Waitlist Available
Has No Placebo

St. John's Rehab at Sunnybrook (+1 Sites)

Marina Wasilewski, PhD

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