Amidate

General Anesthesia

Treatment

1 FDA approval

0 Active Studies for Amidate

Treatment for

General Anesthesia

What is Amidate

EtomidateThe Generic name of this drug

Treatment SummaryImidazole is a type of drug used as an anesthetic and hypnotic. It is known to have little impact on the cardiovascular system, blood gases, or breathing. It is sometimes used to put a patient to sleep during medical procedures.

Etomidateis the brand name

image of different drug pills on a surface

Amidate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Etomidate

1996

Approved as Treatment by the FDA

Etomidate, also known as Etomidate, is approved by the FDA for 1 uses like General Anesthesia .

General Anesthesia

Effectiveness

How Amidate Affects PatientsEtomidate is a drug used to cause unconsciousness so that anesthesia can be administered. It works by affecting the level of the reticular-activating system in the brain. Its effects last longer than thiopental and methohexital, but not as long as barbituates or propofol. The drug causes unconsciousness quickly, with recovery taking place soon after as a result of its metabolism and redistribution in the body. It does not induce analgesia.

How Amidate works in the bodyEtomidate binds to a special region of the GABA receptor, which controls the flow of chloride ions in and out of cells. By binding to this region, etomidate keeps the chloride ion channel open longer. This increases the inhibitory effects of GABA, which reduces activity in the thalamus.

When to interrupt dosage

The proposed measure of Amidate is contingent upon the diagnosed condition. The amount of dosage fluctuates, in accordance with the method of delivery (e.g. Injection, solution or Solution - Intravenous) detailed in the table below.

Condition

Dosage

Administration

General Anesthesia

2.0 mg/mL, , 4.0 mg/mL

Injection - Intravenous, Injection, Intravenous, , Injection, solution, Injection, solution - Intravenous, Solution, Solution - Intravenous

Warnings

There are 20 known major drug interactions with Amidate.

Common Amidate Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Etomidate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Deutetrabenazine

Major

The risk or severity of sedation and somnolence can be increased when Etomidate is combined with Deutetrabenazine.

Ethanol

Major

Etomidate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Iobenguane

Major

The therapeutic efficacy of Iobenguane can be decreased when used in combination with Etomidate.

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Etomidate is combined with Oliceridine.

Amidate Toxicity & Overdose RiskTaking etomidate may cause pain during injection, muscle spasms, and decreased activity of the adrenal gland up to 6 hours afterwards.

image of a doctor in a lab doing drug, clinical research

Amidate Novel Uses: Which Conditions Have a Clinical Trial Featuring Amidate?

Currently, 4 clinical trials are underway to investigate the potential of Amidate as an effective treatment for General Anesthesia.

Condition

Clinical Trials

Trial Phases

General Anesthesia

0 Actively Recruiting

Amidate Reviews: What are patients saying about Amidate?

5Patient Review

7/18/2012

Amidate for Anxious

I've used this product for over 25 years to manage my anxiety. It's been integral in allowing me to have a successful career without putting undue stress on my family.

5Patient Review

4/28/2011

Amidate for Anxious

meprobamate has been an effective anti-depressant for me and my mother when other drugs have not worked.

5Patient Review

4/19/2017

Amidate for Anxious

I currently can't afford this medication, as a 30-day supply costs over $400. My doctor has substituted generic Valium instead, which was originally prescribed to me over 25 years ago for skeletal pain and muscle tension. I don't prefer the generic Valium, as it doesn't work as well for me with far more side effects. I just don't understand the drug companies at all.

5Patient Review

10/8/2021

Amidate for Anxious

Meprobamate is an excellent medication for stress and anxiety. It allows me to move on from negativity and disappointment, especially regarding people. I only use it occasionally when I really need it, as opposed to taking advantage of the drug.

5Patient Review

4/28/2011

Amidate for Anxious

Meprobamate has been an effective anti-depressant for me, and it's something that I've turned to after other drugs haven't worked.

View All Reviews

Patient Q&A Section about amidate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Etomidate and propofol?

"Propofol causes smooth and rapid induction, rapid recovery, and cerebro-protective effect, but it can also lead to hypotension, bradycardia, respiratory depression, and pain on injection. Etomidate is a hypnotic agent that leads to minimal histamine release and a very stable hemodynamic profile."

Answered by AI

What class of medication is Etomidate?

"Etomidate is an intravenous anesthetic agent that has a very short duration of action and is not a barbiturate."

Answered by AI

What is Amidate used for?

"This medicine is used to induce general anesthesia and may be used alone or with other medications. It belongs to a class of drugs called systemic general anesthetics."

Answered by AI