Alprazolam

Panic Disorder, Generalized Anxiety Disorder
Treatment
12 Active Studies for Alprazolam

What is Alprazolam

AlprazolamThe Generic name of this drug
Treatment SummaryAlprazolam is a medication used to treat anxiety and panic disorders. It should not be taken with medicines that contain ketoconazole or itraconazole. When stopping Alprazolam, the dose should be tapered down gradually to avoid withdrawal symptoms. Side effects of Alprazolam use can include drowsiness, so it should not be taken with alcohol, as this can lead to coma or death. Alprazolam was approved by the FDA in 1981.
Alprazolamis the brand name
image of different drug pills on a surface
Alprazolam Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Alprazolam
Alprazolam
1981
518

Effectiveness

How Alprazolam Affects PatientsAlprazolam is a type of medicine that affects the brain's communication system to reduce anxiety. It is important to be aware that taking alprazolam with opioids can lead to severe sleepiness, breathing problems, coma, and even death. People with existing breathing problems are also more at risk of these effects. Taking alprazolam can also cause drowsiness, so it is important to not drive or use heavy machinery while taking it. It is also possible to become addicted to alprazolam, so it should be monitored carefully. When stopping or reducing the dose of alprazolam,
How Alprazolam works in the bodyGABA receptors help control the flow of electrical signals in the brain by either making them stronger (excitatory) or weaker (inhibitory). GABA receptors are made up of different parts that come together to form a channel. These channels allow chloride ions to move in and out of cells, creating a change in electrical charge. When GABA binds to these receptors, it opens up the channel, allowing chloride ions to quickly travel through and cause the cell to become more negatively charged. This causes a decrease in electrical signals, which is an inhibitory effect. Benzodiazepines can also bind to these receptors, which can have both therapeutic and unwanted

When to interrupt dosage

The advocated measure of Alprazolam is contingent upon the diagnosed condition. The amount of dosage depends on the delivery process delineated in the table beneath.
Condition
Dosage
Administration
Generalized Anxiety Disorder
, 1.0 mg, 2.0 mg, 3.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL
Oral, , Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Kit, Solution, concentrate, Solution, concentrate - Oral
Panic Disorder
, 1.0 mg, 2.0 mg, 3.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL
Oral, , Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Kit, Solution, concentrate, Solution, concentrate - Oral

Warnings

Alprazolam Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Alprazolam may interact with Pulse Frequency
There are 20 known major drug interactions with Alprazolam.
Common Alprazolam Drug Interactions
Drug Name
Risk Level
Description
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Alprazolam.
Azelastine
Major
Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Alprazolam.
Carbamazepine
Major
The metabolism of Carbamazepine can be decreased when combined with Alprazolam.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Alprazolam.
Alprazolam Toxicity & Overdose RiskTaking too much alprazolam can lead to extreme drowsiness, confusion, clumsiness, and even coma and death. Mixing alprazolam with alcohol increases the risk of an overdose. If someone has taken an overdose, their breathing, pulse, and blood pressure should be monitored, and they may be given stomach pumping and fluids intravenously. If their blood pressure becomes too low, they may need medications to raise it again. In severe cases, a special medication called flumazenil may also be used to treat the overdose. In rats, the toxic dose of alprazolam is between
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Alprazolam Novel Uses: Which Conditions Have a Clinical Trial Featuring Alprazolam?

47 active clinical trials are assessing Alprazolam as a potential treatment for Generalized Anxiety Disorder.
Condition
Clinical Trials
Trial Phases
Generalized Anxiety Disorder
4 Actively Recruiting
Not Applicable, Phase 2
Panic Disorder
9 Actively Recruiting
Not Applicable

Alprazolam Reviews: What are patients saying about Alprazolam?

5Patient Review
12/20/2017
Alprazolam for Anxious
I was really struggling to get through everyday life before this treatment. I couldn't even leave my bed some days, let alone go to work. And when I did manage to make it in, I would have panic attacks and black out. But now I feel like I have my life back!
5Patient Review
1/22/2019
Alprazolam for Chronic Trouble Sleeping
This treatment is effective, but can be addictive. Withdrawal symptoms are really tough to deal with.
5Patient Review
1/25/2019
Alprazolam for Anxiousness associated with Depression
I primarily use this medication for sleep; however, I occasionally have to take it for anxiety as well. The fact that I'm only allotted 30 per month is really problematic because it means that I constantly have to ration my usage.
5Patient Review
2/28/2021
Alprazolam for Anxiousness associated with Depression
This drug has been a life-saver for my dog (and me). She used to be terrified of thunderstorms, but now she's much more calm.
5Patient Review
12/20/2017
Alprazolam for Anxious
This treatment has been life-changing for me. I used to be terrified to leave my bed every day, and now I'm living my life without fear.
View All Reviews
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Patient Q&A Section about alprazolam

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is alprazolam used for in adults?

"Alprazolam is a medication used to treat anxiety and panic disorder. It is a benzodiazepine, a class of drugs that act on the brain and nervous system to produce a calming effect."

Answered by AI

Is alprazolam and Xanax the same?

"The chronic use of Xanax can lead to physical dependence and tolerance.

The active ingredient in Xanax is alprazolam, which is used to treat anxiety symptoms that are caused by a chemical imbalance in the brain. Over time, chronic use of Xanax can lead to physical dependence and tolerance."

Answered by AI

Is alprazolam a strong drug?

"Xanax is a very powerful Benzodiazepine that is mostly used to treat Generalized Anxiety Disorder (GAD), panic disorders, and insomnia. It can be very addictive if used for a long time, so Xanax addiction and abuse is something to be worried about."

Answered by AI

Is alprazolam used as a sleeping pill?

"Zolpidem (Ambien) and alprazolam (Xanax) are both used to treat insomnia. However, Xanax is not officially approved to treat insomnia; it is only approved to treat panic attacks and anxiety disorders. These two medications come from different drug classes; Ambien is a sedative/hypnotic while Xanax is a benzodiazepine."

Answered by AI

Clinical Trials for Alprazolam

Have you considered Alprazolam clinical trials? We made a collection of clinical trials featuring Alprazolam, we think they might fit your search criteria.
Have you considered Alprazolam clinical trials? We made a collection of clinical trials featuring Alprazolam, we think they might fit your search criteria.
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