Alcaine

Local Anaesthesia therapy

Treatment

0 Active Studies for Alcaine

What is Alcaine

Proparacaine

The Generic name of this drug

Treatment Summary

Proparacaine is a medication used to numb the surface of the eyes. It is applied directly to the eye in the form of an ophthalmic solution containing 0.5% of the hydrochloride salt.

Alcaine

is the brand name

Alcaine Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Alcaine

Proparacaine

1973

24

Effectiveness

How Alcaine Affects Patients

Proparacaine works by blocking the electrical signals that allow nerve cells to send messages, acting as a local anesthetic. This drug works by binding to certain sodium channels in nerve cells, preventing them from sending messages.

How Alcaine works in the body

We don't know the exact way that proparacaine works, but studies show that it stops sodium ions from passing through nerve cells. This prevents the cells from creating an action potential, which is necessary for the body to feel pain.

When to interrupt dosage

The prescribed measure of Alcaine is contingent upon the ascertained disorder. The dosage fluctuates as per the technique of administration (e.g. Ophthalmic or Solution / drops) presented in the table beneath.

Condition

Dosage

Administration

Local Anaesthesia therapy

, 5.0 mg/mL, 0.5 %

, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ophthalmic; Topical, Solution - Ophthalmic; Topical

Warnings

There are 4 known major drug interactions with Alcaine.

Common Alcaine Drug Interactions

Drug Name

Risk Level

Description

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Proparacaine is combined with Oliceridine.

Daridorexant

Minor

The risk or severity of CNS depression can be increased when Proparacaine is combined with Daridorexant.

Fluoxetine

Moderate

Proparacaine may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.

Ziprasidone

Moderate

The risk or severity of adverse effects can be increased when Proparacaine is combined with Ziprasidone.

image of a doctor in a lab doing drug, clinical research

Alcaine Novel Uses: Which Conditions Have a Clinical Trial Featuring Alcaine?

0 active clinical trials are presently examining the potential of Alcaine to offer Local Anesthetic effects.

Condition

Clinical Trials

Trial Phases

Local Anaesthesia therapy

0 Actively Recruiting

Alcaine Reviews: What are patients saying about Alcaine?

5

Patient Review

5/12/2009

Alcaine for Anesthesia of the Cornea of the Eye

I went for my bi-annual eye check-up and the optometrist used Alcaine drops to check the pressure in my eyes. Within seconds, my eyes started swelling up and watering profusely, followed by the rest of my face!

1

Patient Review

9/4/2009

Alcaine for Anesthesia of the Cornea of the Eye

I had a foreign object in my eye that scratched my cornea. I flushed it out for days with no relief and was in immense pain for an entire week before going to the ER. The doctors there dropped two drops of Alcaine in my eye and I felt instantaneous relief.

1

Patient Review

5/5/2010

Alcaine for Anesthesia of the Cornea of the Eye

I had an allergic reaction to this medication that manifested as hives all over my body. The next day, I woke up with swollen lips and heavy eyelids. Despite lots of water, the reaction persisted.

1

Patient Review

6/4/2014

Alcaine for Anesthesia of the Cornea of the Eye

I have to get my eyes checked for glaucoma every six months, and the doctor always uses this treatment. Unfortunately, it gives me severe headaches every time. I'm hoping to find a substitute that doesn't have this side effect.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about alcaine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Alcaine used for?

"It works by numbing the eye.

Alcaine is a prescription drug that is used to treat the symptoms associated with foreign bodies, suture removal, and deep ophthalmic anesthesia. It can be used alone or in conjunction with other medications. Alcaine belongs to a class of drugs known as ophthalmic anesthetics. It works by numbing the eye."

Answered by AI

How long does Alcaine eye drops last?

"The anesthetic effect of Alcaine will decrease rapidly, typically around 15 minutes after the last drop is administered into your eye(s)."

Answered by AI

What is proparacaine used for?

"Proparacaine eye drops are used to numb the eye before surgery, certain tests, or procedures. The eye drops are used to prevent pain during the procedure. Proparacaine belongs to the group of medicines called local anesthetics. It works by blocking the pain signals at the nerve endings in the eye."

Answered by AI

How often can you use Alcaine eye drops?

"How often can you use proparacaine droplets? Your provider will give you 1 drop per dose, every 5 to 10 minutes for up to 5 to 7 doses, for short procedures on your eye. You won't be able to take any more afterwards because this medication is only for short-term use."

Answered by AI