Animal Protein for Cognitive Impairment
What You Need to Know Before You Apply
What is the purpose of this trial?
Minimally processed animal protein is a premier source of essential macro and micronutrients in the diet and is important, especially to older adults who are at increased risk of nutritional deficiency and age-related physiological changes. Our central hypothesis is that adding lean animal protein within a healthy diet following macronutrient recommendations for Americans will enhance nutrient adequacy and attenuate markers of cognitive decline. This is a retrospective study leveraging samples collected from the feeding trial NCT05581953. PI for both studies are the same.
Will I have to stop taking my current medications?
Yes, you will need to stop taking medications, as the trial excludes participants who use medications.
Is animal protein safe for human consumption?
Research on various animal proteins, including bovine-plasma protein, suggests they can be consumed in relatively high amounts without causing gastrointestinal issues or gut barrier problems. However, a small increase in blood pressure was noted with bovine-plasma protein, possibly due to its salt content, indicating a potential health concern.12345
How does the treatment Minimally Processed Animal Protein differ from other treatments for cognitive impairment?
Minimally Processed Animal Protein is unique because it focuses on using animal-derived proteins, which may influence cognitive function by affecting brain-related mechanisms such as nerve growth and oxidative stress. Unlike other treatments, it emphasizes the potential benefits of specific dietary proteins on cognitive health, which is a novel approach compared to standard pharmaceutical interventions.26789
What data supports the effectiveness of the treatment Minimally Processed Animal Protein for cognitive impairment?
Research suggests that adequate protein intake is important for brain health, and low protein levels are linked to cognitive decline. Studies have shown that higher protein consumption may reduce the risk of brain changes associated with Alzheimer's disease, indicating that protein-rich diets could help maintain cognitive function in older adults.26101112
Who Is on the Research Team?
Moul Dey, Ph.D
Principal Investigator
South Dakota State University
Are You a Good Fit for This Trial?
This trial is for older adults who are at risk of cognitive decline and nutritional deficiencies. Participants should be interested in following a meal plan based on dietary guidelines, which includes lean animal protein. Specific eligibility details are not provided.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a diet with minimally processed animal protein to assess its effect on cognitive decline biomarkers
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Minimally Processed Animal Protein
Find a Clinic Near You
Who Is Running the Clinical Trial?
South Dakota State University
Lead Sponsor