Addyi

Hypoactive Sexual Desire Disorder
Treatment
2 FDA approvals
1 Active Study for Addyi

What is Addyi

FlibanserinThe Generic name of this drug
Treatment SummaryFlibanserin is a medication used to treat low sexual desire in premenopausal women. It was approved by the FDA in 2015 and was originally developed as an antidepressant. Flibanserin works by altering the levels of serotonin, norepinephrine and dopamine in the brain, which can result in an increase in sexual desire.
Addyiis the brand name
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Addyi Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Addyi
Flibanserin
2015
1

Approved as Treatment by the FDA

Flibanserin, otherwise known as Addyi, is approved by the FDA for 2 uses including Hypoactive Sexual Desire Disorder (HSDD) and Hypoactive Sexual Desire Disorder .
Hypoactive Sexual Desire Disorder (HSDD)
Hypoactive Sexual Desire Disorder

Effectiveness

How Addyi works in the bodyFlibanserin binds to serotonin receptors in the brain, allowing it to act as a stimulant on some receptors and a blocker on others. Specifically, it binds to 5-HT1A and 5-HT2A receptors and can block the activity of dopamine and other hormones. This effect is believed to balance out serotonin levels in the brain and aid in reward processing.

When to interrupt dosage

The measure of Addyi is contingent upon the identified affliction. The amount of dosage differs, as detailed in the table beneath, as per the technique of delivery (e.g. Oral or Tablet, film coated - Oral).
Condition
Dosage
Administration
Hypoactive Sexual Desire Disorder
, 100.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral

Warnings

There are 20 known major drug interactions with Addyi.
Common Addyi Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Flibanserin.
Axitinib
Major
The serum concentration of Axitinib can be increased when it is combined with Flibanserin.
Azelastine
Major
Flibanserin may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Bendamustine
Major
The serum concentration of Bendamustine can be increased when it is combined with Flibanserin.
Binimetinib
Major
The serum concentration of Binimetinib can be increased when it is combined with Flibanserin.
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Addyi Novel Uses: Which Conditions Have a Clinical Trial Featuring Addyi?

A single investigation is assessing the potential of Addyi to alleviate Hypoactive Sexual Desire Disorder.
Condition
Clinical Trials
Trial Phases
Hypoactive Sexual Desire Disorder
1 Actively Recruiting
Phase 2

Addyi Reviews: What are patients saying about Addyi?

5Patient Review
12/2/2018
Addyi for Disorder of Low Sexual Desire in Premenopausal Woman
This treatment has been great! I'm more aroused and my sex life has improved because of it.
5Patient Review
9/13/2022
Addyi for Disorder of Low Sexual Desire in Premenopausal Woman
I'll be taking this treatment tomorrow and I'm already hopeful based on the reviews and research I've done. The price is a bit high, but from what I can tell it's worth it. I'll come back in a month to update my review after seeing how well it works for me and if there are any side effects.
5Patient Review
6/29/2017
Addyi for Disorder of Low Sexual Desire in Premenopausal Woman
I've been on this medication for two months now and I've definitely seen an uptick in my sex drive. No negative side effects to speak of, only good things!
5Patient Review
6/6/2022
Addyi for Disorder of Low Sexual Desire in Premenopausal Woman
About three weeks after starting this medication, I noticed a significant increase in my libido. It's been great to feel that intimacy with my husband again. The only downside is that I sometimes feel fatigue during the day, but it's worth it for the benefits I've seen so far.
2Patient Review
9/15/2022
Addyi for Disorder of Low Sexual Desire in Premenopausal Woman
I was pretty disappointed with Addyi. I took it for the full ten weeks and didn't notice any changes whatsoever--definitely not what I was expecting or hoping for. It did help me sleep, though when I stopped taking it I had a lot of trouble sleeping again. Zero side effects, which is good, but overall just not worth it in my opinion.
View All Reviews
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Patient Q&A Section about addyi

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does Addyi last?

"Addyi lasts for around 11 hours. If taken with food, its absorption into the body increases. After 3 days of taking the medication, there is a steady level of the drug in the body.Jan 14, 2022"

Answered by AI

What does Addyi do to your body?

"Aug 18, 2021 Addyi is a non-hormonal MSAA that corrects an imbalance of neurotransmitters related to sexual excitement. It does this by increasing levels of dopamine and norepinephrine while decreasing levels of serotonin."

Answered by AI

How much does Addyi cost?

"If you have insurance, you will only have to pay $20 a month for Addyi. If you do not have insurance, you can still purchase Addyi for a maximum price of $99 a month. You can also buy three months worth of Addyi for the price of two."

Answered by AI

How fast does Addyi work?

"The clinical trials data suggests that it may take up to four weeks to see results from taking Addyi, and up to eight or twelve weeks to see the maximum effect."

Answered by AI

Clinical Trials for Addyi

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