Respiratory Muscle Strength Training for Breast Cancer

SP
Overseen BySandra P. Morgan, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Florida
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether exercises can prevent breathing muscle weakness in adults newly diagnosed with breast cancer who are planning for surgery. Participants will either engage in respiratory muscle strength training, which involves specific exercises to strengthen breathing muscles, or practice Box Breathing, a deep breathing technique. The trial aims to determine which method better maintains strong breathing muscles before and after surgery. This trial suits adults diagnosed with breast cancer who are comfortable doing breathing exercises at home. As an unphased trial, it offers a unique opportunity to contribute to innovative research that could enhance pre-surgical care for breast cancer patients.

Do I have to stop taking my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that breathing exercises to strengthen the muscles used for breathing are generally safe for people with breast cancer. In studies with breast cancer survivors, these exercises have improved breathing muscle strength without harmful side effects. Most participants handle the exercises well. Although specific data on risks is lacking, these exercises resemble regular physical activities, which are usually safe. This trial tests breathing exercises, not a new drug. These exercises are typically safe and well-tolerated by most people.12345

Why are researchers excited about this trial?

Unlike the standard treatments for breast cancer that typically focus on surgery, chemotherapy, and radiation, respiratory muscle strength training offers a unique pre-surgery approach. Researchers are excited about this method because it aims to enhance patients' respiratory health and potentially improve recovery outcomes by strengthening the muscles involved in breathing. This approach is distinct because it prepares the body for surgery through exercises that are easy to perform and non-invasive, potentially leading to better post-operative recovery without the side effects associated with more aggressive treatments.

What evidence suggests that this trial's treatments could be effective for preventing respiratory muscle weakness in breast cancer surgery patients?

This trial will compare respiratory muscle strength training with Box breathing exercises for breast cancer patients. Studies have shown that training the muscles used for breathing can help breast cancer survivors strengthen these muscles after surgery. Research indicates that combining this training with aerobic exercise improves overall fitness and reduces fatigue in patients recovering from breast cancer treatment. One study found that breast cancer survivors often have weaker breathing muscles and tend to breathe faster and more shallowly, which this training can help improve. Overall, exercise, including breathing muscle training, enhances quality of life and physical function in breast cancer patients.16789

Who Is on the Research Team?

SK

Sandra K. Morgan, PhD

Principal Investigator

University of Florida

Are You a Good Fit for This Trial?

Adults newly diagnosed with breast cancer who are preparing for surgery can join this trial. They should be able to perform breathing exercises at home and keep a diary of their activity. Specific details about who cannot participate are not provided.

Inclusion Criteria

I am an adult over 18, recently diagnosed with breast cancer, speak English, and can follow study instructions.

Exclusion Criteria

Pregnancy
I recently had a collapsed lung.
Individuals who cannot complete at least ten exercise sessions.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants perform respiratory muscle strength training or Box breathing exercises for at least 2 weeks at home

2-4 weeks
3 visits (in-person at home)

Follow-up

Participants are monitored for changes in respiratory strength, dyspnea, diaphragmatic thickness, thoracic expansion, anxiety, depression, and quality of life

2 weeks after surgery
1 visit (in-person at home)

What Are the Treatments Tested in This Trial?

Interventions

  • Deep Breathing Exercises
  • Respiratory Muscle Strength Training
Trial Overview The study is testing if respiratory muscle strength training is better than deep breathing exercises (Box Breathing) in preventing post-surgery respiratory muscle weakness in adults with breast cancer.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Respiratory muscle strength trainingExperimental Treatment1 Intervention
Group II: Box Breathing ExercisesActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Florida

Lead Sponsor

Trials
1,428
Recruited
987,000+

Citations

Using Inspiratory Muscle Training to Improve Respiratory ...In post-operative breast cancer survivors, respiratory muscle training combined with aerobic training increases respiratory muscle strength and ...
Comparing Respiratory Muscle Strength Training to Deep ...These results will also allow us to assess the impact of respiratory strength training on the older breast cancer patient. If successful ...
Potential Therapeutic Role of Respiratory Muscle Training in ...In addition, the results showed that breast cancer survivors had lower respiratory and limb muscle strength and more rapid and shallow breathing pattern.
Adjunctive Inspiratory Muscle Training During a ...Exercise training programs are effective in improving physical fitness and reducing fatigue after breast cancer treatment.
Effectiveness of exercise modalities on breast cancer patient ...Overall exercise significantly improves the HRQOL, CRF and physical function in patients with BC. HRQOL was improved with all exercise types.
Outcomes of physical exercises on initiation, progression, and ...Evidence has suggested that participation in physical activity is correlated with a decrease in reappearance and fatality rates of breast cancer patients.
Exercise Training Improves Strength and Quality of Life for ...Supervised aerobic and resistance exercise can improve the physical performance and strength of patients living with metastatic breast ...
A single bout of resistance or high-intensity interval training ...A single bout of RT or HIIT can increase levels of anti-cancer myokines and reduce the growth of MDA-MB-231 cells in vitro in survivors of ...
Comparative Efficacy of Different Exercise Therapies for ...Exercise has a significantly positive impact on the CRF of breast cancer survivors. MICT, M–V, HIIT, and M–V + RE had better efficacy than usual ...
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