Acular

Eye Pain, Inflammation, corneal refractive surgery + 20 more

Treatment

2 FDA approvals

20 Active Studies for Acular

What is Acular

Ketorolac

The Generic name of this drug

Treatment Summary

Titanium dioxide is a natural oxide of titanium found in minerals like ilmenite, rutile and anatase. It is used as a white pigment in paint, cosmetics and other products, and is known by its other names such as titanium white or Pigment White 6 (PW6).

Toradol

is the brand name

Acular Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Toradol

Ketorolac

1991

316

Approved as Treatment by the FDA

Ketorolac, also called Toradol, is approved by the FDA for 2 uses like caudal epidural block therapy and induction of Nerve Block .

caudal epidural block therapy

Used to treat caudal epidural block therapy in combination with Bupivacaine

induction of Nerve Block

Used to treat induction of Nerve Block in combination with Bupivacaine

Effectiveness

How Acular works in the body

Sunscreen agents help to protect your skin from harmful UV rays by absorbing the radiation within a certain range of wavelengths. The type and amount of UV radiation absorbed depend on the molecular structure of the sunscreen.

When to interrupt dosage

The recommended dosage of Acular is contingent upon the established condition, such as Wound, Atopic Dermatitis and abrasions. The amount of dosage is contingent on the technique of delivery specified in the accompanying table.

Condition

Dosage

Administration

Cataract Surgery

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Miosis disorder

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Macular Edema, Cystoid

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Seasonal Allergic Conjunctivitis

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Ocular Itching

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Eye Pain

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Intraocular Lens Replacement

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Macular Edema, Cystoid

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

postoperative ocular pain

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Pain

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

caudal epidural block therapy

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Macular Edema

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Acute Coryza

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Pupil

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

induction of Nerve Block

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

induction of Local Anaesthesia

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Pericarditis Acute

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Inflammation

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

corneal refractive surgery

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Induced Hyperthermia

, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL

Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, , Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Liquid - Intramuscular, Solution - Intramuscular, Injection, solution, concentrate - Intraocular, Injection, solution, concentrate, Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Epidural; Infiltration; Intramuscular; Intravenous, Oral, Liquid, Infiltration; Intramuscular; Intravenous; Topical, Kit, Kit - Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution - Intravenous, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical

Warnings

Acular Contraindications

Condition

Risk Level

Notes

Heart failure

Do Not Combine

Hyperkalemia

Do Not Combine

Renal Insufficiency

Do Not Combine

Hemorrhagic Disorders

Do Not Combine

Kidney Failure

Do Not Combine

A History of Gastric or Duodenal Ulcers

Do Not Combine

Liver Diseases

Do Not Combine

Major Surgery

Do Not Combine

Pulse Frequency

Do Not Combine

Gastrointestinal Hemorrhage

Do Not Combine

Crohn's Disease

Do Not Combine

suspected cerebrovascular bleeding

Do Not Combine

active Gastrointestinal Bleeding

Do Not Combine

NSAID-Induced Asthma

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

incomplete hemostasis

Do Not Combine

Coronary Artery Bypass Grafting

Do Not Combine

Gastrointestinal Perforation

Do Not Combine

Pulse Frequency

Do Not Combine

Hemorrhage

Do Not Combine

Peptic Ulcer

Do Not Combine

Pulse Frequency

Do Not Combine

Labour

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Third trimester of pregnancy

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Ketorolac may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Ketorolac may interact with Pulse Frequency

There are 20 known major drug interactions with Acular.

Common Acular Drug Interactions

Drug Name

Risk Level

Description

Aceclofenac

Major

The risk or severity of adverse effects can be increased when Ketorolac is combined with Aceclofenac.

Acemetacin

Major

The risk or severity of adverse effects can be increased when Ketorolac is combined with Acemetacin.

Acetylsalicylic acid

Major

The risk or severity of adverse effects can be increased when Ketorolac is combined with Acetylsalicylic acid.

Alclofenac

Major

The risk or severity of adverse effects can be increased when Ketorolac is combined with Alclofenac.

Alminoprofen

Major

The risk or severity of adverse effects can be increased when Ketorolac is combined with Alminoprofen.

Acular Toxicity & Overdose Risk

The toxic dose of titanium dioxide when inhaled in rats is greater than 100ug/kg. Studies have shown that titanium dioxide can cause changes to bronchi and trachea in animals, and may potentially cause cancer in humans.

image of a doctor in a lab doing drug, clinical research

Acular Novel Uses: Which Conditions Have a Clinical Trial Featuring Acular?

74 active clinical trials are currently examining the efficacy of Acular in providing Ultraviolet Therapy, relieving abrasions and treating Sunburn.

Condition

Clinical Trials

Trial Phases

Inflammation

56 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3, Phase 4

Induced Hyperthermia

0 Actively Recruiting

caudal epidural block therapy

5 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2

Intraocular Lens Replacement

0 Actively Recruiting

Acute Coryza

0 Actively Recruiting

Macular Edema, Cystoid

0 Actively Recruiting

induction of Nerve Block

0 Actively Recruiting

Pupil

0 Actively Recruiting

Local Anaesthesia therapy

0 Actively Recruiting

corneal refractive surgery

0 Actively Recruiting

Seasonal Allergic Conjunctivitis

0 Actively Recruiting

Eye Pain

0 Actively Recruiting

postoperative ocular pain

0 Actively Recruiting

Eye

0 Actively Recruiting

Ocular Itching

0 Actively Recruiting

Pericarditis Acute

1 Actively Recruiting

Phase 2, Phase 3

Miosis disorder

0 Actively Recruiting

Macular Edema, Cystoid

0 Actively Recruiting

Macular Edema

1 Actively Recruiting

Phase 1, Phase 2

Cataract Surgery

3 Actively Recruiting

Not Applicable

Acular Reviews: What are patients saying about Acular?

5

Patient Review

12/4/2008

Acular for Allergic Conjunctivitis

I've used Acular for two decades now to great effect. It's the only thing that helps with my seasonal allergies and itchy eyes, but the increased cost is really becoming a problem.

4.7

Patient Review

10/30/2007

Acular for Allergic Conjunctivitis

The only downside is the burning sensation you feel for a few seconds after applying the drops to your eyes.

4.3

Patient Review

5/8/2014

Acular for Inflammation of the Eye Following Surgery

Acular has been working great for me post-operatively. I've been using it for three weeks to manage pain and inflammation following a trabeculectomy, and so far I haven't had any issues with pain or inflammation since my surgery.

3

Patient Review

11/9/2014

Acular for Inflammation of the Eye Following Surgery

My 82 year old mother had a severe reaction to Acular eye drops the day after starting to take it, was very dizzy, even when laying down room was spinning, and she had trouble describing how bad she felt. Her doctor said to stop taking it immediately. One day later she still experienced some dizziness, and two days later she is feeling better.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about acular

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is ACULAR eye drops a steroid?

"Acular is a non-steroidal anti-inflammatory drug, not a steroid. Steroids and NSAIDs are often used for similar conditions, including eye pain or inflammation, though they are different medications."

Answered by AI

What is ACULAR eye drops used for?

"ACULAR is a non-steroidal anti-inflammatory drug (NSAID) used to relieve eye inflammation following surgery in adults. The active ingredient in ACULAR is ketorolac trometamol."

Answered by AI

How long can I use ACULAR eye drops?

"Use the ACULAR® eye drops for as long as your doctor prescribes, which is usually 2-4 weeks."

Answered by AI

Is ACULAR an anti-inflammatory?

"Acular is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve eyeitching caused by seasonal allergies. It is also used to reduce swelling, pain,and burning or stinging after cataract surgery or corneal refractive surgery."

Answered by AI

Clinical Trials for Acular

Image of Montana State University in Bozeman, United States.

Haskap Berries for Exercise Performance Recovery

18 - 35
All Sexes
Bozeman, MT

The purpose of this clinical trial is to determine how certain food items affect oxidative stress, inflammation, and performance recovery from exercise induced muscle damage in a resistance trained population. The main questions The investigators aim to answer are the following: * Do Haskaps speed the recovery of oxidative stress and inflammation markers after an intense lower body workout in resistance trained adults? * Do Haskaps speed the recovery of performance measures after an intense lower body workout in resistance trained adults? * The data collected in this investigation may also be used to ask additional questions not yet identified. For example, the investigators may use the stored samples to evaluate how the blood metabolites of participants differ before and after intense exercise. These additional questions are called secondary analyses. Please note that no genetic analysis will be conducted and racial and ethnic differences among participants will not be used in any secondary analyses. Researches will compare Haskap juice to a color, flavor and carbohydrate matched placebo to see if Haskaps speed recovery in inflammation, oxidative stress and performance. * Participants will be asked to drink either Haskap juice or placebo and follow a low polyphenolic diet * Participants will perform an intense resistance workout * Participants will have their blood drawn before and after the workout * Performance will be analyzed at 24, 48 and 72 hours after the workout

Recruiting
Paid Trial

Montana State University

Mary P Miles

Image of Byers Eye Institute in Palo Alto, United States.

LLM-Based Education for Cataract Surgery

18+
All Sexes
Palo Alto, CA

Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance. Other "premium" lenses have various benefits such as reducing the need for glasses but usually require out-of-pocket costs. The combined busy outpatient clinic and complexity of artificial lens choices in the ever-changing world of cataract surgery tends to lead patients confused about their available lens options. There is an abundance of educational material present in premium lenses, however these are limited by accessibility and are standardized at single educational levels. Therefore in the present study, we want to test whether giving patients a short LLM powered AI-guided explanation from Custom GPT from OpenAI of lens options prior to their consultation with their doctor can improve visit efficiency, physician explanation and patient understanding of lens options. We will compare two groups: standard of care versus standard of care plus AI education. The LLM in this study is intended to provide supplemental information about premium intraocular lens(IOLs) options to study participants, and is no means supposed to replace a health care professional in the diagnosis, cure, treatment, and/or mitigation of disease. Study is analogous to giving a verified health pamphlet to a patient for them to view and learn different IOL options, in other words, facilitating patient understanding of their options. The LLM will be trained by several health care professionals and MD specialists to provide sufficient instructions. Sources will include verified online resources and MD information. The investigators hope to learn if a large language model-based educational tool can improve visit efficiency, physician explanation and patient understanding of intraocular lens options. New knowledge of this study could guide how cataract counseling is delivered in the future and may help clinics spend more time on individualized questions instead of repeating generic information.

Waitlist Available
Has No Placebo

Byers Eye Institute

Robert T Chang, MD

Image of University of New Brunswick in Fredericton, Canada.

Mediterranean Diet for Toddler Health

24 - 36
All Sexes
Fredericton, Canada

Toddlerhood (ages 2-3) is a critical window when the gut microbiome is still developing and eating habits are being established. Yet, many Canadian toddlers eat diets high in sugar and salt, which may affect long-term health. This study will test whether a MED diet can improve dietary inflammation, gut health, and body composition in toddlers and whether a tailored nutrition education program for parents can help families maintain healthy eating patterns. In this study, toddlers will be randomly assigned to a 3-week MED diet or their usual diet. Families in the MED diet group will receive free meal boxes for the 3 weeks, plus guidance from a nutrition researcher through a structured education program. The standard diet group will continue their regular diet with general nutrition advice. Researchers will collect dietary information, body composition assessments, and stool samples to measure gut microbiome composition and metabolites. This first study of a controlled diet intervention in toddlers, combining behavioral support, high-quality food provision, and advanced gut microbiome analysis, will help understand how early diet shapes lifelong eating habits and health, guiding public health strategies and precision nutrition approaches to prevent chronic disease from early life.

Waitlist Available
Has No Placebo

University of New Brunswick

Dr. Maryam Kebbe, PhD, CLC

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Image of McGill University Health Centre in Montreal, Canada.

Dexmedetomidine for Pain Relief

18 - 75
All Sexes
Montreal, Canada

This study will compare three different doses of perineural dexmedetomidine 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg as adjuvants to local anesthetics for ultrasound-guided infraclavicular brachial plexus blocks (ICBs). Our research hypothesis is that 1.33 mcg/kg will provide a 15%-longer duration than 1mcg/kg, which in turn will provide a 15%-longer duration than 0.67 mcg/kg. Since analgesic duration and sensory duration can be influenced by intake of pain medications and surgical trauma to small cutaneous nerves, respectively, we will select motor block duration as the main outcome to better target the action of dexmedetomidine on the brachial plexus.

Phase 2
Recruiting

McGill University Health Centre

Julián Aliste, MD

Image of University of California, San Francisco in San Francisco, United States.

Vision Centers for Eye Care

Any Age
All Sexes
San Francisco, CA

The goal of this clinical trial is to evaluate the effect of vision centers on access to eye care and eye health outcomes in South Asia. The main questions it aims to answer are: 1. Do vision centers increase visits to eyecare centers? 2. Do vision centers increase spectacle ownership and wearing? 3. Do vision centers improve visual acuity of the population? Researchers will compare outcomes in communities randomized to have a vision center is established with communities randomized to delay establishment of a vision center. Outcomes will be assessed through population-based surveys at baseline and after two years as well as through hospital records collected throughout the study period.

Waitlist Available
Has No Placebo

University of California, San Francisco

Kieran O'Brien, PhD, MPH

Image of UConn Health in Farmington, United States.

Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT

The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)

Waitlist Available
Has No Placebo

UConn Health

Cutter Lindbergh, Ph.D.

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Image of Mount Sinai Hospital in Toronto, Canada.

Intrathecal Morphine for Urinary Retention

18+
All Sexes
Toronto, Canada

Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs. The multimodal approach, including single shot or continuous nerve blocks with catheters and spinal or epidural morphine, is a stablished strategy. Although the administration of intrathecal morphine (IM) has been shown to significantly reduce pain scores, it is not free of adverse effects. Postoperative urinary retention (POUR) is possible and might increase the risk of periprosthetic infection. The purpose of this study is to compare patients undergoing rTKAS under spinal anesthesia with IM to patients undergoing the same procedure, under the same anesthetic technique, but with no IM, for POUR and postoperative pain related outcomes. All patients will have single shot and continuous adductor canal block (CACB) and single shot IPACK (interspace between the popliteal artery and the posterior knee capsule) block. The hypothesis is that postoperative pain control is comparable between the groups, with lower incidence of POUR in patients with no IM given.

Phase 3
Recruiting

Mount Sinai Hospital

Hermann dos Santos Fernandes, MD, PhD

Image of Abcentra Investigational Site in Los Angeles, United States.

Orticumab for Heart Attack

18+
All Sexes
Los Angeles, CA

The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies

Phase 2
Recruiting

Abcentra Investigational Site (+6 Sites)

Abcentra

Image of School of Public Health in Bloomington, United States.

High Salt Intake for High Blood Pressure

60 - 85
All Sexes
Bloomington, IN

Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. Salt is particularly deleterious in older adults who are more likely to exhibit salt-sensitive hypertension. However, salt consumption remains high in the United States. Thus, there is a critical need for strategies to counteract the effects of high dietary salt as consumption is likely not going to decrease. One promising option is ketones, metabolites that are produced in the liver during prolonged exercise and very low-calorie diets. While exercise and low-calorie diets are beneficial, not many people engage in these activities. Limited evidence indicates that ketone supplements improve cardiovascular health in humans. Additionally, published rodent data indicates that ketone supplements prevent high salt-induced increases in blood pressure, blood vessel dysfunction, and kidney injury. Our human pilot data also indicates that high dietary salt reduces intrinsic ketone production, but it is unclear whether ketone supplementation confers humans' protection against high salt similar to rodents. Therefore, the investigators seek to conduct a short-term high-dietary salt study to determine whether ketone supplementation prevents high dietary salt from eliciting increased blood pressure, blood vessel dysfunction, and kidney injury/impaired blood flow. The investigators will also measure inflammatory markers in blood samples and isolate immune cells that control inflammation. Lastly, the investigators will also measure blood ketone concentration and other circulating metabolites that may be altered by high salt, which could facilitate novel therapeutic targets to combat high salt.

Recruiting
Has No Placebo

School of Public Health

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We made a collection of clinical trials featuring Acular, we think they might fit your search criteria.
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