Oxytrol For Women

Nocturia, Urinary Bladder, Overactive, Neurological Disorders + 8 more

Treatment

20 Active Studies for Oxytrol For Women

What is Oxytrol For Women

Oxybutynin

The Generic name of this drug

Treatment Summary

Oxybutynin, also known as Ditropan XL, is a medication used to treat overactive bladder (OAB). OAB is a common condition that causes symptoms like frequent urination and urgency. Oxybutynin was first approved by the FDA in 1975 and is considered a safe and effective treatment for OAB. It can help improve the quality of life for people affected by OAB by relieving their symptoms. It is often the first drug prescribed for OAB.

Ditropan

is the brand name

image of different drug pills on a surface

Oxytrol For Women Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Ditropan

Oxybutynin

1975

256

Effectiveness

How Oxytrol For Women Affects Patients

Oxybutynin helps to relieve symptoms of an overactive bladder, such as frequent and urgent urination, by blocking a certain type of nerve receptor. Taking this drug may cause symptoms of angioedema, so it should be stopped immediately if this occurs. It can also cause anticholinergic effects such as hallucinations, confusion, agitation, and drowsiness, and using heavy machinery should be avoided until the response to oxybutynin is known. The dose may need to be adjusted in some cases.

How Oxytrol For Women works in the body

Oxybutynin works by blocking the effects of a chemical called acetylcholine on bladder muscles, which makes it easier to control urine flow and decreases urgency and frequency of urination. It does this by preventing the chemical from binding to receptors in the bladder muscles. Oxybutynin's active metabolite is N-desethyloxybutynin, which works to relax the bladder and increase its capacity.

When to interrupt dosage

The suggested measure of Oxytrol For Women is contingent upon the diagnosed condition, including Neurological Disorders, Foley Catheterization and Nocturia. The sum of dosage varies according to the method of delivery (e.g. Tablet, extended release or Patch) recorded in the table underneath.

Condition

Dosage

Administration

Spinal Dysraphism

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Urinary Bladder, Overactive

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Neurological Disorders

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

increased frequency of urination

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Foley Catheterization

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Longterm Indwelling Ureteral Stent

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Nocturia

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Bladder Spasms

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Urinary Urgency

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Urinary Incontinence, Urge

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Overactive Bladder Syndrome

, 5.0 mg/mL, 10.0 mg, 15.0 mg, 5.0 mg, 0.39 mg/hour, 0.28 mg/mg, 0.1 mg/mg, 2.5 mg, 0.0907 mg/mg, 10.0 %, 1.0 mg/mL

, Syrup, Oral, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Gel, Gel - Transdermal, Transdermal, Topical, Gel - Topical, Solution, Solution - Oral, Patch - Transdermal, Spray, metered, Spray, metered - Topical, Patch

Warnings

Oxytrol For Women Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Oxybutynin may interact with Pulse Frequency

Urinary Retention

Do Not Combine

uncontrolled narrow-angle glaucoma

Do Not Combine

Gastric Retention

Do Not Combine

There are 20 known major drug interactions with Oxytrol For Women.

Common Oxytrol For Women Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Oxybutynin.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Oxybutynin.

Aclidinium

Major

The risk or severity of adverse effects can be increased when Oxybutynin is combined with Aclidinium.

Alectinib

Major

The metabolism of Alectinib can be decreased when combined with Oxybutynin.

Alpelisib

Major

The metabolism of Alpelisib can be decreased when combined with Oxybutynin.

Oxytrol For Women Toxicity & Overdose Risk

The lowest fatal dose of oxybutynin in rats is 460mg/kg. If someone overdoses on oxybutynin, they may experience confusion, fever, rapid heartbeat, urinary retention, difficulty breathing, paralysis and coma. Immediate supportive care should be provided, as well as activated charcoal and a laxative. There have been two cases of people overdosing on 100mg of oxybutynin, both of which involved alcohol consumption. Both individuals received treatment and fully recovered.

image of a doctor in a lab doing drug, clinical research

Oxytrol For Women Novel Uses: Which Conditions Have a Clinical Trial Featuring Oxytrol For Women?

79 active clinical trials are currently examining the potential of Oxytrol For Women to provide relief from Overactive Bladder Syndrome, Foley Catheterization and Neurological Disorders.

Condition

Clinical Trials

Trial Phases

Nocturia

3 Actively Recruiting

Phase 4, Not Applicable

Bladder Spasms

1 Actively Recruiting

Phase 2

Spinal Dysraphism

0 Actively Recruiting

Urinary Incontinence, Urge

7 Actively Recruiting

Not Applicable, Phase 4

Foley Catheterization

0 Actively Recruiting

Urinary Urgency

2 Actively Recruiting

Not Applicable

Urinary Bladder, Overactive

0 Actively Recruiting

Overactive Bladder Syndrome

32 Actively Recruiting

Phase 3, Not Applicable, Phase 4, Phase 1, Phase 2

Longterm Indwelling Ureteral Stent

0 Actively Recruiting

Neurological Disorders

7 Actively Recruiting

Not Applicable, Phase 2

increased frequency of urination

3 Actively Recruiting

Not Applicable

Oxytrol For Women Reviews: What are patients saying about Oxytrol For Women?

5

Patient Review

2/9/2014

Oxytrol For Women for A Condition of Bladder Dysfunction from Nerve Disorder

I still feel the need to go too much.

5

Patient Review

3/12/2014

Oxytrol For Women for Overactive Bladder

The patches I bought over the counter did nothing for me.

4.3

Patient Review

5/18/2014

Oxytrol For Women for Urine Leakage When there is a Strong Desire to Void

This medication has really helped me out. I'm able to sleep through the night without having to get up every two hours to go to the bathroom.

4

Patient Review

5/28/2014

Oxytrol For Women for Needing to Urinate Immediately

The medication worked well, but the patch itself was uncomfortable to wear.

3.7

Patient Review

11/20/2014

Oxytrol For Women for Overactive Bladder

This treatment helps me more than Interstim

3.7

Patient Review

10/31/2013

Oxytrol For Women for Overactive Bladder

1.3

Patient Review

11/17/2013

Oxytrol For Women for Overactive Bladder

Patient Q&A Section about oxytrol for women

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can you buy Oxytrol over-the-counter?

"The Oxytrol patches for men and women are available in different forms. The men's patch is available only with a doctor's prescription, but the women's patch is available without a prescription or over-the counter (OTC). This product is available in the following dosage forms: Patch, Extended Release."

Answered by AI

What are the side effects of Oxytrol patch?

"You may experience skin redness or irritation, dry mouth, drowsiness, dizziness, blurred vision, headache, weakness, nausea, or constipation when using this medication. If you experience any of these symptoms, tell your doctor or pharmacist."

Answered by AI

How long does it take for Oxytrol to start working?

"It takes approximately one week for the medication to reach steady levels in your system after you start using Oxytrol patches. The patches deliver the medication slowly through your skin and into your bloodstream over the course of 3-4 days."

Answered by AI

Why was Oxytrol patch discontinued?

"Because sales were not meeting expectations, Bayer AG stopped distributing the over-the-counter version of OXY-TDS in early 2015, after they acquired Merck & Co."

Answered by AI

Clinical Trials for Oxytrol For Women

Image of Cincinnati Urogynecology Associates in Cincinnati, United States.

Nitrous Oxide for Pain During Bladder Botox Injections

18+
Female
Cincinnati, OH

The goal of this clinical trial is to assess if a mix of nitrous oxide and oxygen can improve pain control during bladder Botox injections. The primary question it aims to answer is: Does using nitrous oxide lower the overall level of pain during the procedure? Researchers will compare a 50:50 nitrous oxide/oxygen mixture (administered with the Pro-Nox system) plus standard care (with lidocaine in the bladder) to sham mask plus standard care to see if nitrous oxide works better for lowering pain. Participants will: * Receive their bladder Botox injection in the office setting * Either use nitrous oxide/oxygen plus standard care during the procedure, or sham mask plus standard care * Answer brief questions about pain, anxiety, satisfaction, and willingness to repeat the procedure

Phase 4
Waitlist Available

Cincinnati Urogynecology Associates (+1 Sites)

Have you considered Oxytrol For Women clinical trials?

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Have you considered Oxytrol For Women clinical trials?

We made a collection of clinical trials featuring Oxytrol For Women, we think they might fit your search criteria.
Go to Trials

Have you considered Oxytrol For Women clinical trials?

We made a collection of clinical trials featuring Oxytrol For Women, we think they might fit your search criteria.
Go to Trials