Your session is about to expire
What is Actiq
FentanylThe Generic name of this drug
Treatment SummaryFentanyl is a powerful opioid painkiller developed in the 1950s for the treatment of severe pain and anesthesia. It is similar to morphine and oxycodone, and is commonly used in cancer patients and those who have undergone surgery. Unfortunately, it has also been used as an adulterant in illegal drugs, making it a dangerous drug that can cause fatal overdoses. Fentanyl was approved by the FDA in 1968 and is estimated to cause 11 deaths in Canada each day.
Fentanyl Citrateis the brand name
Actiq Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fentanyl Citrate
Fentanyl
1984
322
Approved as Treatment by the FDA
Fentanyl, commonly known as Fentanyl Citrate, is approved by the FDA for 7 uses which include High Risk Surgery and Anesthetics .High Risk Surgery
Used to treat High Risk Surgery in combination with Oxygen
Anesthetics
Used to treat Anesthetics Agent in combination with Oxygen
Induction of anesthesia therapy
Used to treat Induction of anesthesia therapy in combination with Droperidol
Pain
Helps manage Cancer Related Pain (Breakthrough Pain)
opioid tolerant
Helps manage opioid tolerant
Anesthetic premedication therapy
Used to treat Anesthetic premedication therapy in combination with Droperidol
Anesthesia procedures
Used to treat Maintenance of anesthesia therapy in combination with Droperidol
Effectiveness
How Actiq Affects PatientsFentanyl is a strong painkiller that activates opioid receptors in the body and is effective for several hours at a time. It can be habit-forming and should not be taken with alcohol or sedative medications.
How Actiq works in the bodyFentanyl binds to opioid receptors, blocking nerve signals and reducing pain. It does this by attaching to G-proteins, which turn off enzymes that control how much calcium enters a cell. This causes the cell to become more negatively charged, stopping nerve activity and reducing pain.
When to interrupt dosage
The measure of Actiq is contingent upon the diagnosed ailment, including Anesthesia, Conduction, Preanesthetic Medication and General Anesthesia. The quantity can be seen in the table below, subject to the approach of administration.Condition
Dosage
Administration
Anesthesia procedures
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
Induction of anesthesia therapy
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
Anesthetic premedication therapy
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
High Risk Surgery
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
opioid tolerant
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
Pain
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
General Anesthesia
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
Pain
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
Anesthetics
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
Anesthesia, Conduction
0.025 mg/hour, 0.05 mg/hour, 0.075 mg/hour, , 0.1 mg/hour, 0.0125 mg/hour, 0.1 mg, 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 0.3 mg, 0.012 mg/hour, 0.25 mg/hour, 0.5 mg/hour, 0.75 mg/hour, 0.01 mg/mL, 0.02 mg/mL, 0.025 mg/mL, 0.05 mg/mL, 0.002 mg/mL, 0.003 mg/mL, 0.001 mg/mL, 0.005 mg/mL, 2.55 mg/[USP'U], 5.1 mg/[USP'U], 7.65 mg/[USP'U], 10.2 mg/[USP'U], 1.28 mg/[USP'U], 1.2 mg, 1.6 mg, 0.012 mg, 0.05 mg, 0.075 mg, 0.025 mg, 2.5 mg, 5.0 mg, 7.5 mg, 10.0 mg, 0.0875 mg/hour, 0.04 mg/dose, 0.01 mg/hour, 0.0025 mg/hour, 0.005 mg/hour, 0.0125 mg, 0.04 mg, 0.0375 mg/hour, 0.0625 mg/hour, 0.01 mg, 0.03 mg, 0.1 mg/mL, 0.1 mg/spray, 0.4 mg/spray, 0.2 mg/dose, 0.1 mg/dose, 0.05 mg/dose, 0.037 mg/hour, 0.25 mg/mL
, Transdermal, Patch, extended release, Patch, extended release - Transdermal, Buccal; Oral; Transmucosal, Tablet, Tablet - Buccal; Oral; Transmucosal, Nasal, Spray, Spray - Nasal, Patch, Patch - Transdermal, Oral; Transmucosal, Lozenge, Lozenge - Oral; Transmucosal, Sublingual, Tablet - Sublingual, Intravenous, Injection, solution, Injection, solution - Intravenous, Epidural, Injection, solution - Epidural, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Epidural; Intramuscular; Intravenous, Solution - Epidural; Intramuscular; Intravenous, Solution, Liquid, Liquid - Epidural; Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Film, soluble, Buccal, Film, soluble - Buccal, Tablet - Buccal, Buccal; Sublingual, Tablet - Buccal; Sublingual, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual, Solution - Nasal, Spray - Sublingual, Injection, Injection - Intramuscular; Intravenous, Injection - Intravenous, Tablet, effervescent, Tablet, effervescent - Buccal; Sublingual, Transmucosal, Lozenge - Transmucosal, Film - Buccal, Patch, extended release, electrically controlled, Patch, extended release, electrically controlled - Transdermal, Epidural; Intravenous, Injection, solution - Epidural; Intravenous, Aerosol, spray - Nasal
Warnings
Actiq has thirteen counterindications and should not be used in the presence of the conditions specified in the following table.Actiq ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Fentanyl may interact with Pulse Frequency
short opioid analgesia requirement
Do Not Combine
Asthma
Do Not Combine
Pain
Do Not Combine
Asthma
Do Not Combine
Mental Depression
Do Not Combine
opioid non-tolerant patients
Do Not Combine
known or suspected gastrointestinal obstruction
Do Not Combine
Paralytic Ileus
Do Not Combine
Paralytic Ileus
Do Not Combine
management of acute or intermittent pain
Do Not Combine
Pain
Do Not Combine
respiratory compromise
Do Not Combine
Common Actiq Drug Interactions
Drug Name
Risk Level
Description
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Fentanyl.
Eluxadoline
Major
The risk or severity of constipation can be increased when Fentanyl is combined with Eluxadoline.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Fentanyl is combined with Oliceridine.
Paclitaxel
Major
The metabolism of Paclitaxel can be decreased when combined with Fentanyl.
Sirolimus
Major
The metabolism of Sirolimus can be decreased when combined with Fentanyl.
Actiq Toxicity & Overdose RiskThe toxic dose for fentanyl in rats is 2.91mg/kg when injected and 18mg/kg when taken orally. Since the toxic dose in humans is unknown, it is important to be aware of the signs of an overdose. Symptoms of an overdose may include difficulty breathing, sleepiness, confusion, limp muscles, cold skin, pupil constriction, fluid in the lungs, slow or irregular heartbeat, low blood pressure, obstructed airways, and death. If someone overdoses on fentanyl, they should be given naloxone or nalmefene to counteract the effects of the drug and receive medical support to help them breathe or
Actiq Novel Uses: Which Conditions Have a Clinical Trial Featuring Actiq?
43 active studies are being conducted to assess the potential of Actiq to reduce Pain, provide Anesthetics and act as Preanesthetic Medication.Condition
Clinical Trials
Trial Phases
Induction of anesthesia therapy
0 Actively Recruiting
Pain
0 Actively Recruiting
Anesthesia procedures
0 Actively Recruiting
Pain
0 Actively Recruiting
High Risk Surgery
0 Actively Recruiting
Anesthetic premedication therapy
0 Actively Recruiting
General Anesthesia
3 Actively Recruiting
Not Applicable, Phase 3
Anesthesia, Conduction
0 Actively Recruiting
opioid tolerant
0 Actively Recruiting
Anesthetics
0 Actively Recruiting
Actiq Reviews: What are patients saying about Actiq?
5Patient Review
1/25/2011 This medication is a true godsend for me. I have chronic back pain, and there are days when the level of pain is so high that my oral pain medication doesn't even make a dent. This breakthrough medication has helped me on those days, and I don't know what I would do without it.
5Patient Review
4/8/2011 The lollipop worked great for me, but I was unaware of the damage it was doing to my teeth. I've lost at least eight teeth and have had to spend a lot of money on dental bills (even with insurance). My insurance company stopped covering it because I don't have cancer, but nothing else has worked as well for me.
5Patient Review
5/10/2013 I had been using this medication for five years before stopped. I did it the right way and weaned myself off gradually, so I didn't experience any withdrawal symptoms. However, now that I've been off of the medication for almost three months, my pain has gotten worse again. Now I need to find a new doctor in the area who will prescribe this medication for me. My quality of life has decreased significantly since stopping this medication, and I am desperate for help.
5Patient Review
1/10/20115Patient Review
4/3/2012 I've heard that people can die from mixing Actiq and Xanax. Is this true?
4.7Patient Review
12/25/2011 This is an incredibly effective treatment, especially when used with duragesic patches. I was taking three 600mcg suckers a day as needed, and it's the only thing that touches the breakthrough pain that is just intolerable. However, you've got to have really good insurance because this stuff is $1280 for a box of 30 (that's what they bill our med plan-I copay $10). Stay away from oxycontin and suggest this instead; my pain management doctor says very few plans cover it however.
4.3Patient Review
2/1/2011 I've been using Actiq for a while now, and it's great for when I need quick relief from pain. It's expensive, but if you can swing it, I recommend giving it a try.
4.3Patient Review
11/3/20104Patient Review
1/8/20113Patient Review
10/22/2011 This treatment provides quick relief for chronic pain.
Patient Q&A Section about actiq
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What class drug is Actiq?
"The drug Actiq belongs to a class of drugs known as opioid analgesics, which are drugs that act on the nervous system to relieve pain."
Answered by AI
Is Actiq available?
"The FDA has required a restricted program, called a Risk Evaluation and Mitigation Strategy (REMS), for ACTIQ due to the risk for misuse, abuse, addiction, and overdose."
Answered by AI
What is Actiq prescribed for?
"ACTIQ (fentanyl citrate taken through the mucus membranes) is indicated for the management of breakthrough pain in cancer patients 16 years of age and older who are already receiving and who are tolerant to around-the-clock opioids for their underlying persistent cancer pain."
Answered by AI
Is Actiq an opioid?
"Fentanyl Citrate is a type of opioid that is used to treat pain. It works by attaching to opioid receptors in the brain, spinal cord, and gastrointestinal tract."
Answered by AI