Zipsor

Contusions, Pain, Photophobia + 54 more

Treatment

10 FDA approvals

20 Active Studies for Zipsor

What is Zipsor

Diclofenac

The Generic name of this drug

Treatment Summary

Diclofenac is a type of non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. It works by blocking enzymes, called cyclooxygenases (COX), which produce substances that cause pain and swelling. It is usually prescribed to treat acute and chronic pain from various causes, and is sometimes combined with a stomach-protecting drug called misoprostol to reduce the risk of stomach ulcers. Diclofenac was first approved for use by the FDA in 1988 under the brand name Voltaren.

Voltaren

is the brand name

image of different drug pills on a surface

Zipsor Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Voltaren

Diclofenac

1988

767

Approved as Treatment by the FDA

Diclofenac, also called Voltaren, is approved by the FDA for 10 uses including Osteoarthritis of the Knee and Pain .

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Pain

Helps manage Pain

Postoperative Inflammatory Response

Chronic Pain

Helps manage Pain

Osteoarthritis (OA)

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Stomach Ulcer

Used to treat develop NSAID-induced gastric ulcers in combination with Misoprostol

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Osteoarthritis

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Rheumatoid Arthritis

Cataract Surgery

Effectiveness

How Zipsor Affects Patients

Diclofenac helps reduce pain and fever by reducing inflammation. Unfortunately, it also decreases the amount of protective mucus in the stomach, making it more likely to develop an ulcer.

How Zipsor works in the body

Diclofenac works by blocking the production of molecules called prostaglandins. These molecules are involved in pain and inflammation, so reducing their production reduces these symptoms. Diclofenac also reduces inflammation by preventing white blood cells from entering the affected area and blocking molecules that assist in cell reproduction. It also works on receptors in the brain to reduce fever. All these pathways work together to reduce inflammation and pain.

When to interrupt dosage

The proposed measure of Zipsor is contingent upon the identified condition, for example Joint Pain, Postoperative Inflammatory Response and Osteoarthritis (OA). The quantity of dosage is contingent upon the execution strategy (e.g. Cream; Kit; Solution or Kit; Oil; Solution / drops) featured in the following table.

Condition

Dosage

Administration

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Cataract Surgery

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Acute Coryza

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

radial keratotomy

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Actinic Keratosis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Arthralgia

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Primary Dysmenorrhoea

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Arthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Contusions

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Photophobia

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Inflammation

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Fever

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Postoperative

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Postoperative Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Rheumatoid Arthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Rheumatism

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Radiculopathy

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Osteoarthritis of the Knee

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Postoperative Inflammatory Response

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release - Oral, Tablet, delayed release, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops - Ophthalmic, Solution / drops, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Tablet, extended release, Tablet, extended release - Oral, Patch - Topical, Patch, Capsule, liquid filled, Capsule, liquid filled - Oral, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Kit - Topical, Tablet, sugar coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Capsule - Oral, Capsule, Cream, Cream - Topical, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Oral; Topical, Kit - Oral; Topical, Sublingual, Tablet, coated, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system

Warnings

Zipsor Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Heart failure

Do Not Combine

Crohn's Disease

Do Not Combine

recent history of anal bleeding

Do Not Combine

Hemorrhagic Disorders

Do Not Combine

Gastritis

Do Not Combine

inflammatory lesions of the Rectum

Do Not Combine

active Gastrointestinal Bleeding

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

active Gastrointestinal Perforation

Do Not Combine

Duodenal Ulcer

Do Not Combine

Coronary Artery Bypass Grafting

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

Ulcerative Colitis

Do Not Combine

Liver Diseases

Do Not Combine

Stroke

Do Not Combine

Third trimester of pregnancy

Do Not Combine

Hematochezia

Do Not Combine

Kidney Failure

Do Not Combine

Kidney Failure

Do Not Combine

Anus

Do Not Combine

Ulcer

Do Not Combine

damaged skin

Do Not Combine

Gastric ulcer

Do Not Combine

Peptic Ulcer

Do Not Combine

Hyperkalemia

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Diclofenac may interact with Pulse Frequency

There are 20 known major drug interactions with Zipsor.

Common Zipsor Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Diclofenac.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Diclofenac.

Cyclophosphamide

Major

The metabolism of Cyclophosphamide can be decreased when combined with Diclofenac.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Diclofenac.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Diclofenac.

Zipsor Toxicity & Overdose Risk

Overdosing on Voltaren can lead to symptoms such as fatigue, nausea, vomiting, upper abdominal pain, and bleeding from the digestive tract. In rare cases, patients may experience high blood pressure, kidney damage or failure, shallow breathing, or coma. Treatments for Voltaren overdose include inducing vomiting and activated charcoal, as long as the overdose occurred within the last 4 hours.

image of a doctor in a lab doing drug, clinical research

Zipsor Novel Uses: Which Conditions Have a Clinical Trial Featuring Zipsor?

491 active clinical trials are currently in progress to assess the effectiveness of Zipsor in alleviating Inflammation, Argon Laser Trabeculoplasty and Osteoarthritis of the Knee.

Condition

Clinical Trials

Trial Phases

Inflammation

55 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3, Phase 4

Osteoarthritis of the Knee

77 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Chronic Pain

124 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Rheumatoid Arthritis

58 Actively Recruiting

Not Applicable, Phase 3, Phase 2, Phase 1, Phase 4

Postoperative Pain

20 Actively Recruiting

Phase 4, Phase 2, Phase 1, Phase 3, Not Applicable

Dysmenorrhea

1 Actively Recruiting

Not Applicable

Muscle Pain

3 Actively Recruiting

Phase 4, Not Applicable, Phase 2

Conjunctivitis

0 Actively Recruiting

Musculoskeletal System

1 Actively Recruiting

Not Applicable

corneal refractive surgery

0 Actively Recruiting

Postoperative Inflammatory Response

0 Actively Recruiting

Photophobia

3 Actively Recruiting

Not Applicable

Pain

3 Actively Recruiting

Not Applicable

Stomach Ulcer

0 Actively Recruiting

Rheumatism

0 Actively Recruiting

Juvenile arthritis

8 Actively Recruiting

Phase 2, Not Applicable, Phase 3

radial keratotomy

0 Actively Recruiting

Joints

0 Actively Recruiting

Pericarditis

2 Actively Recruiting

Phase 2, Phase 3

Acute Coryza

0 Actively Recruiting

Zipsor Reviews: What are patients saying about Zipsor?

5

Patient Review

8/30/2013

Zipsor for Inflammation of the Sac Surrounding the Joint - Bursitis

Arthroscopic surgery on both knees led to a diagnosis of Pes anserine bursitis, which was incredibly painful and made it hard to walk. Zipsor relieved the pain and swelling quickly. Even though my insurance doesn't cover the cost, I would still use this medication as needed because it is effective.

5

Patient Review

11/4/2013

Zipsor for Inflammation of the Sac Surrounding the Joint - Bursitis

Zipsor is a really great medication that helps me a lot when the weather changes or if I overdo it with my workout. It's been really helpful in reducing swelling and restoring flexibility to my ankle, which was severely damaged 2.5 years ago. The liquid capsules are much better than the regular tablets, since they don't upset my stomach.

5

Patient Review

11/4/2013

Zipsor for Migraine Headache

I take this for extreme migraines. This is the 3rd medication I've tried and the only one that works.

5

Patient Review

9/5/2017

Zipsor for Pain

This medication has been an absolute wonder for me. It takes care of all my fibromyalgia pain as well as any other aches and pains that I experience. Just be careful to follow the dosing instructions.

5

Patient Review

8/2/2013

Zipsor for Pain

This treatment is pretty effective; it takes away the pain about 75% of the time.

5

Patient Review

8/15/2013

Zipsor for Inflammation of the Sac Surrounding the Joint - Bursitis

Zipsor is the only medication I've found in the past year that has helped me with my arm pain. It's been four days and I'm feeling great, no side effects yet!

4.7

Patient Review

9/20/2013

Zipsor for Joint Damage causing Pain and Loss of Function

The price tag is my only problem with this drug. I'll be looking for something more affordable with my next prescription.

4.3

Patient Review

3/3/2014

Zipsor for Pain

Worked just as well for me as Ibuprophen800, but it's too expensive. Not covered on my new insurance plan. They want me to try Diclofenac

4

Patient Review

12/16/2012

Zipsor for Pain

This drug was much more effective than others I've tried for my lower back pain. The only issue is that it's quite expensive and my insurance doesn't cover it, so I may have to stop using it.

4

Patient Review

5/25/2013

Zipsor for Rheumatic Disease causing Pain & Stiffness in Backbone

I find that this medication is really effective, and I can take it multiple times a day without any issues.

3.3

Patient Review

9/6/2012

Zipsor for Joint Damage causing Pain and Loss of Function

This medicine was effective in reducing my post-operative ankle pain and swelling. However, it comes with the significant side effect of anxiety for me.

3.3

Patient Review

6/24/2013

Zipsor for Pain

I think this medication is great, but my pharmacist says it's too expensive for most people. I pay $100 a month out of pocket, so I get why he feels that way. Hopefully the manufacturer will do something to make it more accessible in the future.

2.3

Patient Review

11/16/2013

Zipsor for Inflammation of the Sac Surrounding the Joint - Bursitis

I didn't find this effective for pain relief, unfortunately. I'm hoping it at least helps with the swelling and my range of motion.

2.3

Patient Review

2/22/2014

Zipsor for Gout

I was given this drug for gout pain, but it didn't seem to help very much.

2

Patient Review

11/13/2012

Zipsor for Joint Damage causing Pain and Loss of Function

I saw some benefits initially, but they quickly faded after starting this treatment.

2

Patient Review

9/6/2013

Zipsor for Pain

I had foot surgery, then my foot got infected and still hurts really badly. I also have herniated disks in my back with scoliosis and arthritis, and this does nothing for any of those pains either.

2

Patient Review

11/21/2012

Zipsor for Joint Damage causing Pain and Loss of Function

I unfortunately had an allergic reaction to this that required medical attention.

1.7

Patient Review

8/14/2013

Zipsor for Pain

This NSAID is really expensive, and it's not even as effective as ibuprofen! I don't understand how this drug stays in business.

1.3

Patient Review

2/6/2013

Zipsor for Migraine Headache

I didn't find this to be an effective treatment for migraines. After using it twice, my migraine was still there.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about zipsor

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How often can you take Zipsor?

"This difference should be taken into consideration when changing strengths or formulations of diclofenac. The only approved dosing regimen for ZIPSOR is 25 mg four times a day."

Answered by AI

What is Zipsor medication used for?

"The text is discussing the drug Zipsor, which is a prescription NSAID. It is used for relief of mild-to-moderate pain in adults."

Answered by AI

What is Zipsor similar to?

"Relafen and Zipsor are NSAIDs used to treat pain, with Relafen being usd more for inflammation and pain caused by arthritis while Zipsor is used more for relief of mild to moderate acute pain."

Answered by AI

What is the difference between Zipsor and diclofenac?

"Zipsor is an NSAID that works by reducing substances in the body that cause pain and inflammation. Zipsor capsules are used to treat mild to moderate acute pain in adults and pediatric patients 12 years of age or older."

Answered by AI

Clinical Trials for Zipsor

Image of University Center for Ambulatory Surgery in Somerset, United States.

Infusion Pump for Postoperative Pain

18+
All Sexes
Somerset, NJ

This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period.. Patients 18 years or older undergoing ACL reconstruction, open shoulder labrum or rotator cuff surgery, arthroscopic rotator cuff repair, proximal or distal patellar realignment surgery, open knee arthrotomy cases (i.e. inside out meniscus repair, osteochondral allograft transplantation (OCA), meniscal allograft transplantation (MAT)) at University Center for Ambulatory Surgery, LLC (UOA) will be reviewed for eligibility. Once identified, potential study subjects will be asked whether they are interested in participating in the project. If the patient agrees, the subject will be given the informed consent to read and sign. Objectives: The primary objective is to compare the effectiveness of postoperative infusion pain pump versus preoperative nerve block in reducing visual analog pain scores/numerical pain rating scale (VAS/NPRS) in the postoperative period. The second objective is to evaluate the requirement of narcotic and non-narcotic analgesic medications between the two groups. Hypotheses: Use of continuous infusion pain pump or single shot peripheral block will result in similar post-operative pain control after outpatient sports medicine surgical cases.

Phase 4
Recruiting

University Center for Ambulatory Surgery

Image of Montana State University in Bozeman, United States.

Haskap Berries for Exercise Performance Recovery

18 - 35
All Sexes
Bozeman, MT

The purpose of this clinical trial is to determine how certain food items affect oxidative stress, inflammation, and performance recovery from exercise induced muscle damage in a resistance trained population. The main questions The investigators aim to answer are the following: * Do Haskaps speed the recovery of oxidative stress and inflammation markers after an intense lower body workout in resistance trained adults? * Do Haskaps speed the recovery of performance measures after an intense lower body workout in resistance trained adults? * The data collected in this investigation may also be used to ask additional questions not yet identified. For example, the investigators may use the stored samples to evaluate how the blood metabolites of participants differ before and after intense exercise. These additional questions are called secondary analyses. Please note that no genetic analysis will be conducted and racial and ethnic differences among participants will not be used in any secondary analyses. Researches will compare Haskap juice to a color, flavor and carbohydrate matched placebo to see if Haskaps speed recovery in inflammation, oxidative stress and performance. * Participants will be asked to drink either Haskap juice or placebo and follow a low polyphenolic diet * Participants will perform an intense resistance workout * Participants will have their blood drawn before and after the workout * Performance will be analyzed at 24, 48 and 72 hours after the workout

Recruiting
Paid Trial

Montana State University

Mary P Miles

Image of University of North Carolina at Chapel Hill in Chapel Hill, United States.

Pain Medicines for Period Pain in Crohn's Disease

18 - 44
Female
Chapel Hill, NC

The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps in women with Crohn's disease. The goal of this study is to identify any challenges in running a larger study. The investigators will track how many people sign up for the study, how well participants follow the study plan, how many people stay in the study, and whether they are able to complete all the study activities, such as taking the medication, submitting samples, and filling out surveys. During the study, participants will undergo a screening visit that includes a blood draw, physical exam, pregnancy test, stool testing, and complete surveys about Crohn's disease and menstrual cycles. Once this visit is complete, the rest of the study will occur at home. Participants will be assigned to take either ibuprofen or acetaminophen to help treat period cramps for four menstrual cycles in a row. Participants will take ibuprofen for two cycles and acetaminophen for two cycles. Participants will know which medication is being taken at any given time, but the order in which they take the medications will be randomly assigned. Before each menstrual cycle, participants will submit a stool sample and fill out a short (\<1 minute) electronic survey. When participants develop period cramps, they will take the assigned medication for three days and fill out short (\<1 minute) electronic surveys about their cramps. After participants finish taking the medication for three days, they will submit another stool sample and fill out two more short (\<1 minute) electronic surveys. After have completing this process for four menstrual cycles, a remote interview with a researcher to give feedback on the study will be conducted.

Waitlist Available
Has No Placebo

University of North Carolina at Chapel Hill

Erica J Brenner, MD, MSCR

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

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We made a collection of clinical trials featuring Zipsor, we think they might fit your search criteria.
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Image of Byers Eye Institute in Palo Alto, United States.

LLM-Based Education for Cataract Surgery

18+
All Sexes
Palo Alto, CA

Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance. Other "premium" lenses have various benefits such as reducing the need for glasses but usually require out-of-pocket costs. The combined busy outpatient clinic and complexity of artificial lens choices in the ever-changing world of cataract surgery tends to lead patients confused about their available lens options. There is an abundance of educational material present in premium lenses, however these are limited by accessibility and are standardized at single educational levels. Therefore in the present study, we want to test whether giving patients a short LLM powered AI-guided explanation from Custom GPT from OpenAI of lens options prior to their consultation with their doctor can improve visit efficiency, physician explanation and patient understanding of lens options. We will compare two groups: standard of care versus standard of care plus AI education. The LLM in this study is intended to provide supplemental information about premium intraocular lens(IOLs) options to study participants, and is no means supposed to replace a health care professional in the diagnosis, cure, treatment, and/or mitigation of disease. Study is analogous to giving a verified health pamphlet to a patient for them to view and learn different IOL options, in other words, facilitating patient understanding of their options. The LLM will be trained by several health care professionals and MD specialists to provide sufficient instructions. Sources will include verified online resources and MD information. The investigators hope to learn if a large language model-based educational tool can improve visit efficiency, physician explanation and patient understanding of intraocular lens options. New knowledge of this study could guide how cataract counseling is delivered in the future and may help clinics spend more time on individualized questions instead of repeating generic information.

Waitlist Available
Has No Placebo

Byers Eye Institute

Robert T Chang, MD

Image of University of New Brunswick in Fredericton, Canada.

Mediterranean Diet for Toddler Health

24 - 36
All Sexes
Fredericton, Canada

Toddlerhood (ages 2-3) is a critical window when the gut microbiome is still developing and eating habits are being established. Yet, many Canadian toddlers eat diets high in sugar and salt, which may affect long-term health. This study will test whether a MED diet can improve dietary inflammation, gut health, and body composition in toddlers and whether a tailored nutrition education program for parents can help families maintain healthy eating patterns. In this study, toddlers will be randomly assigned to a 3-week MED diet or their usual diet. Families in the MED diet group will receive free meal boxes for the 3 weeks, plus guidance from a nutrition researcher through a structured education program. The standard diet group will continue their regular diet with general nutrition advice. Researchers will collect dietary information, body composition assessments, and stool samples to measure gut microbiome composition and metabolites. This first study of a controlled diet intervention in toddlers, combining behavioral support, high-quality food provision, and advanced gut microbiome analysis, will help understand how early diet shapes lifelong eating habits and health, guiding public health strategies and precision nutrition approaches to prevent chronic disease from early life.

Waitlist Available
Has No Placebo

University of New Brunswick

Dr. Maryam Kebbe, PhD, CLC

Have you considered Zipsor clinical trials?

We made a collection of clinical trials featuring Zipsor, we think they might fit your search criteria.
Go to Trials

Have you considered Zipsor clinical trials?

We made a collection of clinical trials featuring Zipsor, we think they might fit your search criteria.
Go to Trials