Yonsa

Castration, Prostatic Neoplasms, Malignant Neoplasms
Treatment
6 FDA approvals
20 Active Studies for Yonsa

What is Yonsa

AbirateroneThe Generic name of this drug
Treatment SummaryAbiraterone is a steroid-based medication used to treat prostate cancer that has become resistant to hormone therapy. It is administered in an acetate salt form, which increases its availability and helps it to be more stable. Abiraterone was approved by the FDA in 2011.
Zytigais the brand name
image of different drug pills on a surface
Yonsa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Zytiga
Abiraterone
2011
43

Approved as Treatment by the FDA

Abiraterone, commonly known as Zytiga, is approved by the FDA for 6 uses such as Castration and Prostatic Neoplasms .
Castration
Used to treat Metastatic Castration Resistant Prostate Cancer (CRPC) in combination with Methylprednisolone
Prostatic Neoplasms
Used to treat High Risk Prostate Cancer in combination with Prednisone
Metastatic Castration Resistant Prostate Cancer (CRPC)
Used to treat Metastatic Castration Resistant Prostate Cancer (CRPC) in combination with Methylprednisolone
Malignant Neoplasms
Used to treat Metastatic Castration Sensitive Prostate Cancer in combination with Prednisone
Metastatic Castration Sensitive Prostate Cancer
Used to treat Metastatic Castration Sensitive Prostate Cancer in combination with Prednisone
High Risk Prostate Cancer
Used to treat High Risk Prostate Cancer in combination with Prednisone

Effectiveness

How Yonsa Affects PatientsAbiraterone has been found to reduce levels of PSA, shrink tumors, reduce the size of bone metastases, and improve pain. Taking abiraterone can also cause a significant increase in hormones related to the adrenal glands, but this can be prevented by taking dexamethasone.
How Yonsa works in the bodyAbiraterone is a drug that blocks an enzyme called CYP17A1. This enzyme helps turn a hormone called 17-hydroxyprognenolone into another hormone called dehydroepiandrosterone (DHEA). By blocking this enzyme, abiraterone decreases the amount of DHEA and other androgens in the body.

When to interrupt dosage

The measure of Yonsa is reliant on the diagnosed affliction. The dosage amount is also contingent upon the technique of administration as demonstrated in the table below.
Condition
Dosage
Administration
Castration
250.0 mg, , 500.0 mg, 125.0 mg, 1000.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Prostatic Neoplasms
250.0 mg, , 500.0 mg, 125.0 mg, 1000.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Malignant Neoplasms
250.0 mg, , 500.0 mg, 125.0 mg, 1000.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral

Warnings

There are 20 known major drug interactions with Yonsa.
Common Yonsa Drug Interactions
Drug Name
Risk Level
Description
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Abiraterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Abiraterone.
Eliglustat
Major
The metabolism of Eliglustat can be decreased when combined with Abiraterone.
Fentanyl
Major
The metabolism of Fentanyl can be decreased when combined with Abiraterone.
Paclitaxel
Major
The metabolism of Paclitaxel can be decreased when combined with Abiraterone.
Yonsa Toxicity & Overdose RiskTaking too much of this drug can block the activity of an enzyme called 17α-hydroxylase, which can lead to an increase in certain hormones. This can cause symptoms such as excessive fluid retention and low potassium levels. Treatment may involve taking medication to block the hormone receptors.
image of a doctor in a lab doing drug, clinical research

Yonsa Novel Uses: Which Conditions Have a Clinical Trial Featuring Yonsa?

There are 30 active studies assessing the potential of Yonsa in Castration Therapy.
Condition
Clinical Trials
Trial Phases
Castration
28 Actively Recruiting
Phase 1, Phase 2, Phase 3
Prostatic Neoplasms
2 Actively Recruiting
Phase 2, Early Phase 1
Malignant Neoplasms
2 Actively Recruiting
Phase 3, Phase 1

Yonsa Reviews: What are patients saying about Yonsa?

5Patient Review
8/22/2019
Yonsa for Simple Partial Seizures
I've been taking this medication for years and it's really helped me. Some of the side effects can be a bit bothersome, but they're nothing compared to what I would experience with other epilepsy medications.
5Patient Review
8/22/2019
Yonsa for Simple Partial Seizures
I've been using this medication for a while now with only some very manageable side effects.
4.7Patient Review
7/25/2016
Yonsa for Convulsive Seizures
I've been taking this medication for a few years now to help with my epilepsy. The 100mg in the morning and 300mg at night has worked well for me, though I did have some issues sleeping when I took them all in the morning. As with any medication, there are always side effects (none of which are fun), but the pros outweigh the cons in my opinion.
4.7Patient Review
2/26/2021
Yonsa for Convulsive Seizures
Zonisamide has been really effective for me in controlling my seizures. I've lost a lot of weight since starting the medication, which is strange, but it's worth it if it means not having to worry about seizures as much.
4.7Patient Review
10/10/2015
Yonsa for Convulsive Seizures
This drug has been amazing for me--I haven't had a seizure in 8 years. I take 6 pills per day, which is a lot, but it's worth it to me. This is the best seizure medication I've tried.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about yonsa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Yonsa chemo?

"Yonsa is neither a chemotherapy drug nor identical to Zytiga, another prostate cancer treatment. Instead, Yonsa is a hormone therapy that contains the same active ingredient."

Answered by AI

Is Yonsa the same as Zytiga?

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Answered by AI

What is Yonsa used for?

"Abiraterone works by preventing the body from making testosterone.

The purpose of this medication is to treat prostate cancer in men. Abiraterone works by inhibiting the body's production of testosterone, a hormone that aids in the growth and spread of prostate cancer."

Answered by AI

Is there a generic for Yonsa?

"Sun's Yonsa is not a generic version of J&J's blockbuster Zytiga, but it is a competitor. They both contain the same active ingredient, abiraterone acetate, but Sun's formulation doesn't run into trouble with J&J's patents. Yonsa is formulated for administration in combination with methylprednisolone."

Answered by AI

Clinical Trials for Yonsa

Have you considered Yonsa clinical trials? We made a collection of clinical trials featuring Yonsa, we think they might fit your search criteria.
Have you considered Yonsa clinical trials? We made a collection of clinical trials featuring Yonsa, we think they might fit your search criteria.
Have you considered Yonsa clinical trials? We made a collection of clinical trials featuring Yonsa, we think they might fit your search criteria.
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