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What is Yonsa
AbirateroneThe Generic name of this drug
Treatment SummaryAbiraterone is a steroid-based medication used to treat prostate cancer that has become resistant to hormone therapy. It is administered in an acetate salt form, which increases its availability and helps it to be more stable. Abiraterone was approved by the FDA in 2011.
Zytigais the brand name
Yonsa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Zytiga
Abiraterone
2011
43
Approved as Treatment by the FDA
Abiraterone, commonly known as Zytiga, is approved by the FDA for 3 uses such as Malignant Neoplasms and High Risk Prostate Cancer .Malignant Neoplasms
Used to treat Metastatic Castration Sensitive Prostate Cancer in combination with Prednisone
High Risk Prostate Cancer
Used to treat High Risk Prostate Cancer in combination with Prednisone
Castration
Used to treat Metastatic Castration Resistant Prostate Cancer (CRPC) in combination with Methylprednisolone
Effectiveness
How Yonsa Affects PatientsAbiraterone has been found to reduce levels of PSA, shrink tumors, reduce the size of bone metastases, and improve pain. Taking abiraterone can also cause a significant increase in hormones related to the adrenal glands, but this can be prevented by taking dexamethasone.
How Yonsa works in the bodyAbiraterone is a drug that blocks an enzyme called CYP17A1. This enzyme helps turn a hormone called 17-hydroxyprognenolone into another hormone called dehydroepiandrosterone (DHEA). By blocking this enzyme, abiraterone decreases the amount of DHEA and other androgens in the body.
When to interrupt dosage
The measure of Yonsa is reliant on the diagnosed affliction. The dosage amount is also contingent upon the technique of administration as demonstrated in the table below.Condition
Dosage
Administration
High Risk Prostate Cancer
250.0 mg, , 500.0 mg, 125.0 mg, 1000.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Castration
250.0 mg, , 500.0 mg, 125.0 mg, 1000.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Malignant Neoplasms
250.0 mg, , 500.0 mg, 125.0 mg, 1000.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Warnings
There are 20 known major drug interactions with Yonsa.Common Yonsa Drug Interactions
Drug Name
Risk Level
Description
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Abiraterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Abiraterone.
Eliglustat
Major
The metabolism of Eliglustat can be decreased when combined with Abiraterone.
Fentanyl
Major
The metabolism of Fentanyl can be decreased when combined with Abiraterone.
Paclitaxel
Major
The metabolism of Paclitaxel can be decreased when combined with Abiraterone.
Yonsa Toxicity & Overdose RiskTaking too much of this drug can block the activity of an enzyme called 17α-hydroxylase, which can lead to an increase in certain hormones. This can cause symptoms such as excessive fluid retention and low potassium levels. Treatment may involve taking medication to block the hormone receptors.
Yonsa Novel Uses: Which Conditions Have a Clinical Trial Featuring Yonsa?
There are 30 active studies assessing the potential of Yonsa in Castration Therapy.Condition
Clinical Trials
Trial Phases
High Risk Prostate Cancer
0 Actively Recruiting
Malignant Neoplasms
2 Actively Recruiting
Phase 2, Phase 3
Castration
21 Actively Recruiting
Phase 1, Phase 2, Phase 3
Yonsa Reviews: What are patients saying about Yonsa?
5Patient Review
8/22/2019 I've been taking this medication for years and it's really helped me. Some of the side effects can be a bit bothersome, but they're nothing compared to what I would experience with other epilepsy medications.
5Patient Review
8/22/2019 I've been using this medication for a while now with only some very manageable side effects.
4.7Patient Review
7/25/2016 I've been taking this medication for a few years now to help with my epilepsy. The 100mg in the morning and 300mg at night has worked well for me, though I did have some issues sleeping when I took them all in the morning. As with any medication, there are always side effects (none of which are fun), but the pros outweigh the cons in my opinion.
4.7Patient Review
2/26/2021 Zonisamide has been really effective for me in controlling my seizures. I've lost a lot of weight since starting the medication, which is strange, but it's worth it if it means not having to worry about seizures as much.
4.7Patient Review
10/10/2015 This drug has been amazing for me--I haven't had a seizure in 8 years. I take 6 pills per day, which is a lot, but it's worth it to me. This is the best seizure medication I've tried.
4.7Patient Review
9/5/2017 The lack of side effects is very much appreciated with this medication. The only complaint I have is that it can make me drowsy when I first wake up.
4.7Patient Review
7/25/2016 I've been taking this medication for a few years now to manage my epilepsy. I take 100 mg in the morning and 300 mg at night. When I took all of them in the morning, I had sleep problems, but that's better than seizures. Like any epilepsy medication, there are some side effects; however, they're not as bad as the alternative.
4.7Patient Review
2/26/2021 Despite the fact that I have to crush my pills or open capsules, this medicine has been working well for me. It's controlled my seizures and I've even lost weight!
4.7Patient Review
9/5/2017 The best thing about this medicine is that it has very few side effects. The only one I really notice is that it makes me sleepy when I first wake up.
4.7Patient Review
10/10/2015 This drug has kept me seizure-free for eight years, and I firmly believe it's saved my life. I take six 100mg pills per day, which goes through a lot of pills quickly. That's why I only gave it four stars instead of five; I wish it were more affordable. But overall, it's been an amazing medication for me and far better than any other seizure control drugs I've tried in the past.
4.3Patient Review
8/15/2017 I haven't had a seizure in years, but I have lost a lot of weight and I'm always tired. It's also hard to focus and my speech has been slurred.
4.3Patient Review
8/15/2017 This medication has been great for my epilepsy, no seizures in years. However, I've also experienced some pretty severe weight loss as a result, which isn't ideal. Additionally, I often feel tired and have trouble concentrating or speaking clearly.
4Patient Review
1/13/2022 I've been taking zonisamide for the past 5 or 6 years. It's worked until about 6 ago when I had to get kidney stone surgery--which was very painful. I recently had a ultrasound and apparently have several stones in my body even after the surgery. Other than the kidney stones, this medicine helps a lot.
4Patient Review
1/13/2022 I've been taking this zonisamide for the past 5 or 6 years now. It's worked fine until about 6 ago when I had to get kidney stone surgery. Very painful, 3 which were the size of a quarter. I recently had a ultrasound before my Urology appointment and I apparently have now even after the surgery several in my body. Other then the kidney stones this medicine helps a lot.
3.7Patient Review
4/16/2022 I've been taking this medication for a little while now. I was instructed to take it at night, but found that it gave me terrible heartburn. My neurologist then said to try taking it with milk, which worked until I became intolerant to lactose. Now, I'm trying different juices and sodas, but everything seems to make my stomach upset and gives me restless legs at night.
3.7Patient Review
3/29/2018 While this medication did stop my seizures, the side effects were absolutely not worth it. I suffered from depression that got worse and worse until I realized it was a result of the medication. If you value your mental health at all, steer clear of this drug.
3.7Patient Review
11/16/2018 Great seizure control on a low dose. However, the side effects were really tough to deal with. It caused me a lot of pain and made it hard to enjoy my life.
3.7Patient Review
11/16/2018 This medication did a great job of controlling my seizures. However, the side effects were really bad. I had throat pain, itchy and burning skin, bone pain, depression, hostility, irritability, and weird perceptions. The mood issues were the worst. I also had severe petechiae. I was taken off of it and am now searching for a good complimentary treatment to go with the kepra.
3.7Patient Review
4/16/2022 I've been taking this medication for a while now, and it's helped me a lot. I originally took it with water at night, but that gave me terrible heartburn so my neurologist suggested milk instead. That worked until I became lactose intolerant though. Now I'm trying different juices and sodas, but everything seems to make me sick to my stomach and I get restless legs at night, so the last thing I need is sugar and caffeine.
3.7Patient Review
3/29/2018 The medication stopped my seizures but the side effects were horrible. It caused a deep depression that grew worse, until I finally realized it was from the medication and got it lowered. I would not suggest this to a student, or anybody. I had thick brain fog everyday, making it hard to talk to people and concentrate. On top of that I was always so tired and always felt so sad on this medication, even when I got it lowered! Would not suggest!!
3.3Patient Review
7/23/2016 I've had to up my dosage to 600mg a day in order to keep my seizures under control. The downside is that I'm now prone to kidney stones.
3.3Patient Review
7/23/2016 I've had to up my dosage to 600mg per day in order to keep my seizures under control. However, this unfortunately means that I'm now prone to kidney stones.
Patient Q&A Section about yonsa
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Yonsa chemo?
"Yonsa is neither a chemotherapy drug nor identical to Zytiga, another prostate cancer treatment. Instead, Yonsa is a hormone therapy that contains the same active ingredient."
Answered by AI
Is Yonsa the same as Zytiga?
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Answered by AI
What is Yonsa used for?
"Abiraterone works by preventing the body from making testosterone.
The purpose of this medication is to treat prostate cancer in men. Abiraterone works by inhibiting the body's production of testosterone, a hormone that aids in the growth and spread of prostate cancer."
Answered by AI
Is there a generic for Yonsa?
"Sun's Yonsa is not a generic version of J&J's blockbuster Zytiga, but it is a competitor. They both contain the same active ingredient, abiraterone acetate, but Sun's formulation doesn't run into trouble with J&J's patents. Yonsa is formulated for administration in combination with methylprednisolone."
Answered by AI