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What is Unithroid
LevothyroxineThe Generic name of this drug
Treatment SummaryLevothyroxine is a synthetic version of a thyroid hormone called thyroxine. It is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough hormones. Symptoms of hypothyroidism can include fatigue, increased heart rate, depression, dry skin and hair, muscle cramps, constipation, weight gain, memory impairment, and feeling cold. Levothyroxine is designed to imitate the ratio of thyroxine and triiodothyronine (T3) hormones naturally produced by the human thyroid gland, which helps regulate heart rate, blood pressure and other body functions. Prior to the development of
Thyrolaris the brand name
Unithroid Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Thyrolar
Levothyroxine
1969
1177
Approved as Treatment by the FDA
Levothyroxine, also known as Thyrolar, is approved by the FDA for 3 uses including Malignant Neoplasms and Hypothyroidism .Malignant Neoplasms
Hypothyroidism
Helps manage Hypothyroidism
euthyroid Goitre
Helps manage euthyroid Goitre
Effectiveness
How Unithroid Affects PatientsLevothyroxine is a synthetic hormone that mimics natural thyroid hormones to help maintain normal levels when the body does not produce enough. It can have serious side effects if taken in the wrong dose, so it is important to closely monitor the dose and the body's response. Too much levothyroxine can cause an increased heart rate, heart wall thickness, and other heart problems, especially in those with existing heart conditions. It can also reduce bone density, increase calcium and phosphorus levels, and affect blood sugar levels. It is important to start with a lower dose to avoid these issues and carefully monitor the body's response to any changes in
How Unithroid works in the bodyLevothyroxine is a synthetic form of thyroid hormone which helps to treat people with an underactive thyroid (hypothyroidism). It works by increasing the metabolism of cells in the body, helping to regulate things like body temperature, energy levels, and brain function. It also helps with the growth and development of the fetus and newborn. Symptoms of hypothyroidism which can be treated with levothyroxine include slow speech, fatigue, weight gain, hair loss, dry skin, and sensitivity to cold.
Thyroid hormones work in two ways. First, they enter the cell nucleus and bind to areas
When to interrupt dosage
The suggested measure of Unithroid is dependent upon the diagnosed affliction, including Comatose, Edematous Fibrosclerotic Panniculopathy (Cellulite) and Adiposity. The quantity of dosage can be found in the table below, contingent upon the technique of administration.Condition
Dosage
Administration
Hypothyroidism
, 0.025 mg, 0.05 mg, 0.075 mg, 0.088 mg, 0.1 mg, 0.112 mg, 0.125 mg, 0.15 mg, 0.175 mg, 0.2 mg, 0.3 mg, 0.137 mg, 0.038 mg, 0.019 mg, 0.057 mg, 0.038 mCi, 0.5 mg, 0.2 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 0.0095 mg, 0.013 mg, 0.076 mg, 0.0125 mg, 0.114 mg, 0.15 mg/mL, 0.137 mg/mL, 0.175 mg/mL, 0.112 mg/mL, 0.125 mg/mL, 0.088 mg/mL, 0.075 mg/mL, 0.05 mg/mL, 0.025 mg/mL, 0.013 mg/mL, 0.04 mg/mL, 0.02 mg/mL, 0.0375 mg/mL, 0.0625 mg/mL, 0.044 mg/mL
, Oral, Tablet, Tablet - Oral, Topical, Tablet - Topical, Intravenous, Liquid, Liquid - Intravenous, Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Capsule, Capsule - Oral, Solution, Solution - Oral, Injection - Intravenous, Injection, Injection, solution - Intravenous, Injection, solution, Solution - Intramuscular; Intravenous
Malignant Neoplasms
, 0.025 mg, 0.05 mg, 0.075 mg, 0.088 mg, 0.1 mg, 0.112 mg, 0.125 mg, 0.15 mg, 0.175 mg, 0.2 mg, 0.3 mg, 0.137 mg, 0.038 mg, 0.019 mg, 0.057 mg, 0.038 mCi, 0.5 mg, 0.2 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 0.0095 mg, 0.013 mg, 0.076 mg, 0.0125 mg, 0.114 mg, 0.15 mg/mL, 0.137 mg/mL, 0.175 mg/mL, 0.112 mg/mL, 0.125 mg/mL, 0.088 mg/mL, 0.075 mg/mL, 0.05 mg/mL, 0.025 mg/mL, 0.013 mg/mL, 0.04 mg/mL, 0.02 mg/mL, 0.0375 mg/mL, 0.0625 mg/mL, 0.044 mg/mL
, Oral, Tablet, Tablet - Oral, Topical, Tablet - Topical, Intravenous, Liquid, Liquid - Intravenous, Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Capsule, Capsule - Oral, Solution, Solution - Oral, Injection - Intravenous, Injection, Injection, solution - Intravenous, Injection, solution, Solution - Intramuscular; Intravenous
Comatose
, 0.025 mg, 0.05 mg, 0.075 mg, 0.088 mg, 0.1 mg, 0.112 mg, 0.125 mg, 0.15 mg, 0.175 mg, 0.2 mg, 0.3 mg, 0.137 mg, 0.038 mg, 0.019 mg, 0.057 mg, 0.038 mCi, 0.5 mg, 0.2 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 0.0095 mg, 0.013 mg, 0.076 mg, 0.0125 mg, 0.114 mg, 0.15 mg/mL, 0.137 mg/mL, 0.175 mg/mL, 0.112 mg/mL, 0.125 mg/mL, 0.088 mg/mL, 0.075 mg/mL, 0.05 mg/mL, 0.025 mg/mL, 0.013 mg/mL, 0.04 mg/mL, 0.02 mg/mL, 0.0375 mg/mL, 0.0625 mg/mL, 0.044 mg/mL
, Oral, Tablet, Tablet - Oral, Topical, Tablet - Topical, Intravenous, Liquid, Liquid - Intravenous, Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Capsule, Capsule - Oral, Solution, Solution - Oral, Injection - Intravenous, Injection, Injection, solution - Intravenous, Injection, solution, Solution - Intramuscular; Intravenous
euthyroid Goitre
, 0.025 mg, 0.05 mg, 0.075 mg, 0.088 mg, 0.1 mg, 0.112 mg, 0.125 mg, 0.15 mg, 0.175 mg, 0.2 mg, 0.3 mg, 0.137 mg, 0.038 mg, 0.019 mg, 0.057 mg, 0.038 mCi, 0.5 mg, 0.2 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 0.0095 mg, 0.013 mg, 0.076 mg, 0.0125 mg, 0.114 mg, 0.15 mg/mL, 0.137 mg/mL, 0.175 mg/mL, 0.112 mg/mL, 0.125 mg/mL, 0.088 mg/mL, 0.075 mg/mL, 0.05 mg/mL, 0.025 mg/mL, 0.013 mg/mL, 0.04 mg/mL, 0.02 mg/mL, 0.0375 mg/mL, 0.0625 mg/mL, 0.044 mg/mL
, Oral, Tablet, Tablet - Oral, Topical, Tablet - Topical, Intravenous, Liquid, Liquid - Intravenous, Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Capsule, Capsule - Oral, Solution, Solution - Oral, Injection - Intravenous, Injection, Injection, solution - Intravenous, Injection, solution, Solution - Intramuscular; Intravenous
Adiposity
, 0.025 mg, 0.05 mg, 0.075 mg, 0.088 mg, 0.1 mg, 0.112 mg, 0.125 mg, 0.15 mg, 0.175 mg, 0.2 mg, 0.3 mg, 0.137 mg, 0.038 mg, 0.019 mg, 0.057 mg, 0.038 mCi, 0.5 mg, 0.2 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 0.0095 mg, 0.013 mg, 0.076 mg, 0.0125 mg, 0.114 mg, 0.15 mg/mL, 0.137 mg/mL, 0.175 mg/mL, 0.112 mg/mL, 0.125 mg/mL, 0.088 mg/mL, 0.075 mg/mL, 0.05 mg/mL, 0.025 mg/mL, 0.013 mg/mL, 0.04 mg/mL, 0.02 mg/mL, 0.0375 mg/mL, 0.0625 mg/mL, 0.044 mg/mL
, Oral, Tablet, Tablet - Oral, Topical, Tablet - Topical, Intravenous, Liquid, Liquid - Intravenous, Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Capsule, Capsule - Oral, Solution, Solution - Oral, Injection - Intravenous, Injection, Injection, solution - Intravenous, Injection, solution, Solution - Intramuscular; Intravenous
Cellulite
, 0.025 mg, 0.05 mg, 0.075 mg, 0.088 mg, 0.1 mg, 0.112 mg, 0.125 mg, 0.15 mg, 0.175 mg, 0.2 mg, 0.3 mg, 0.137 mg, 0.038 mg, 0.019 mg, 0.057 mg, 0.038 mCi, 0.5 mg, 0.2 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 0.0095 mg, 0.013 mg, 0.076 mg, 0.0125 mg, 0.114 mg, 0.15 mg/mL, 0.137 mg/mL, 0.175 mg/mL, 0.112 mg/mL, 0.125 mg/mL, 0.088 mg/mL, 0.075 mg/mL, 0.05 mg/mL, 0.025 mg/mL, 0.013 mg/mL, 0.04 mg/mL, 0.02 mg/mL, 0.0375 mg/mL, 0.0625 mg/mL, 0.044 mg/mL
, Oral, Tablet, Tablet - Oral, Topical, Tablet - Topical, Intravenous, Liquid, Liquid - Intravenous, Intramuscular; Intravenous, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Capsule, Capsule - Oral, Solution, Solution - Oral, Injection - Intravenous, Injection, Injection, solution - Intravenous, Injection, solution, Solution - Intramuscular; Intravenous
Warnings
Unithroid has four contraindications. It should not be ingested when suffering from any of the conditions enumerated in the following table.Unithroid ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Heart Attack
Do Not Combine
untreated subclinical or overt thryrotoxicosis
Do Not Combine
Adrenal gland hypofunction
Do Not Combine
Common Unithroid Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be decreased when it is combined with Levothyroxine.
Bendamustine
Major
The serum concentration of Bendamustine can be decreased when it is combined with Levothyroxine.
Berotralstat
Major
The serum concentration of Berotralstat can be decreased when it is combined with Levothyroxine.
Binimetinib
Major
The serum concentration of Binimetinib can be decreased when it is combined with Levothyroxine.
Bortezomib
Major
The serum concentration of Bortezomib can be decreased when it is combined with Levothyroxine.
Unithroid Toxicity & Overdose RiskThe lethal dose of this drug in rats is 20 mg/kg when taken orally. Overdosing may cause an increase in metabolic activity similar to that of a thyroid disorder. Symptoms of this disorder include weight loss, increased appetite, increased heart rate and blood pressure, tremors, insomnia, and fever.
Unithroid Novel Uses: Which Conditions Have a Clinical Trial Featuring Unithroid?
Fifteen active experiments are being conducted to investigate the potential of Unithroid in ameliorating Edematous Fibrosclerotic Panniculopathy (Cellulite), Hypothyroidism and Comatose states.Condition
Clinical Trials
Trial Phases
Cellulite
0 Actively Recruiting
Comatose
0 Actively Recruiting
euthyroid Goitre
0 Actively Recruiting
Malignant Neoplasms
0 Actively Recruiting
Adiposity
7 Actively Recruiting
Not Applicable, Phase 4
Hypothyroidism
7 Actively Recruiting
Not Applicable, Phase 4, Phase 2
Unithroid Reviews: What are patients saying about Unithroid?
5Patient Review
12/29/2020 I've tried a few different ablation treatments over the years, and this one is by far the best. Whenever I have any issues now, it's usually because I'm not taking it correctly. The generic version of this treatment wasn't as consistent, so I stick with the brand name.
5Patient Review
1/23/2019 Unithroid has been a godsend. After trying other treatments and not getting results, I was very pleased with how this medication made me feel. Energized, clear-minded, decreased appetite, overall feeling great - I really can't stress enough how happy I am with the results.
4Patient Review
7/25/2011 The medicine I was taking (synthroid) was great, but the drug store substituted it for this generic stuff that doesn't work as well.
3.7Patient Review
11/20/2017 Unithroid has helped my energy levels and general well-being, but I'm now facing rapid hair loss. it's been five months since starting the medication, and over the last three weeks my hair has fallen out so quickly that I have bald spots and am on my way to being completely bald around my face and neckline.
3Patient Review
7/27/2013 I have been on thyroid medication for 19 years and have switched to generic a few times. Each time I switch, my symptoms start again and my TSH levels go out of whack. The savings is just not worth the trouble or the suffering.
2.7Patient Review
11/29/2016 I'm on this medication, and it's causing some serious side effects like a rapid heart rate, insomnia, and mood changes. I've already talked to my doctor about it, but I don't know if I should keep taking it or ask for something else. The upside is that I'm less fatigued, but the anxiety and negative thoughts are not worth it.
2.3Patient Review
2/19/2010 I had radiation treatment for hyperthyroidism and a goiter nine years ago, and I've been on generic and synthroid ever since. My doctor keeps changing my dosage, and I don't think the treatment is ever going to get me to a "normal" state, whatever that really is.
2Patient Review
11/20/2009 I have experienced some pretty unfortunate side effects, like hair loss and weight gain. mood swings. I really don't enjoy taking this drug, and wish anyone else who has to take it all the best. It's terrible and should be removed from shelves.
2Patient Review
5/9/2014 I experienced zero benefits from this treatment.
1.7Patient Review
8/31/2010 I have been losing my hair ever since the beginning of my hypothyroid disease,now that it has been removed I am currently taking Unithriod the hair loss is worse,extreme dry skin and slight weight gain too! I will request that my Dr. change my script to Synthriod.I have read that there is a difference.I will update to let everyone know the result.
1.7Patient Review
1/23/2014 I experienced the same problems as others who have posted here. I was taking Unithroid instead of my usual brand, Synthroid, and within a few weeks all my symptoms came back. It now costs $375 more per year to get the synthroid. If there's no difference between the two brands, why should consumers be Charged more?
1.7Patient Review
8/12/20091Patient Review
3/17/2020 I was forced to switch from synthroid to unithroid by my insurance company, and I very quickly began experiencing a whole host of negative side effects. My endocrinologist ran another thyroid test after I'd been taking unithroid for two and a half weeks, and it showed that my TSH had dropped from 1.290 to 0.152. Going back on synthroid now - do not take this medication!
1Patient Review
8/31/2019 Unithroid made my symptoms so much worse to the point where I was struggling to breathe, and experiencing debilitating leg cramps. This drug should not be on the market.
Patient Q&A Section about unithroid
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is there a difference between Synthroid and UNITHROID?
"Both Unithroid and Synthroid are brand names for the drug levothyroxine. The active ingredient in both medications is levothyroxine, but some of the inactive ingredients are different."
Answered by AI
Does UNITHROID have any side effects?
"Some of the potential side effects of taking Unithroid include: -Hair loss (usually temporary) -Headache -Problems sleeping (insomnia) -Nervousness -Irritability -Fever -Hot flashes -Sweating -Heart palpitations -Changes in how often you menstruate -Appetite and weight changes"
Answered by AI
Is UNITHROID a t3 or T4?
"The active ingredient in Unithroid is levothyroxine, a synthetic version of the thyroid hormone thyroxine (T4). It is chemically identical to the T4 produced naturally in the human thyroid gland."
Answered by AI
Is UNITHROID brand or generic?
"The choice between using a generic or name-brand levothyroxine drug to treat hypothyroidism requires careful consideration. Levothyroxine is sold under various brand names, including Synthroid, Levoxyl, Unithroid, and Levothroid."
Answered by AI