SBRT for Breast Cancer
(SBRT BREAST Trial)
Trial Summary
Do I need to stop my current medications for the SBRT breast cancer trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.
What data supports the effectiveness of the treatment Stereotactic Body Radiation Therapy (SBRT) for breast cancer?
Is SBRT generally safe for humans?
How is the treatment SBRT for breast cancer different from other treatments?
SBRT (Stereotactic Body Radiation Therapy) for breast cancer is unique because it delivers highly precise radiation doses to the tumor, potentially allowing patients who might not qualify for breast-conserving surgery to receive effective treatment. It is minimally invasive and can be combined with chemotherapy before surgery to determine the maximum safe dose, offering a novel approach compared to traditional radiation therapies.1011121314
What is the purpose of this trial?
This trial is testing a focused radiation treatment for breast cancer patients who don't have surgery. It aims to see if this treatment is safe and effective by giving high doses of radiation in a few sessions. The study will follow patients over several years to monitor results. The treatment is being explored for its effectiveness in delaying the switch to other treatments in breast cancer patients.
Research Team
Alexander M. Stessin
Principal Investigator
Stony Brook Cancer Center
Eligibility Criteria
This trial is for adults with invasive breast cancer that can't be removed by surgery or who aren't good candidates for surgery. Participants must have a life expectancy over 6 months, understand and sign consent, and women of childbearing age must use contraception. It's not for those with breast implants in the affected area, life expectancy under 6 months, inadequate imaging, body habitus issues preventing treatment planning, pregnant or breastfeeding women, or those unable to follow study requirements.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Radiation
Participants receive stereotactic body radiation therapy (SBRT) to a dose of 40 Gy over the course of 5 fractions
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Stereotactic Body Radiation Therapy (SBRT)
Stereotactic Body Radiation Therapy (SBRT) is already approved in United States, European Union, Canada, Japan for the following indications:
- Prostate cancer
- Lung cancer
- Liver cancer
- Pancreatic cancer
- Spinal tumors
- Prostate cancer
- Lung cancer
- Liver cancer
- Pancreatic cancer
- Spinal tumors
- Prostate cancer
- Lung cancer
- Liver cancer
- Pancreatic cancer
- Spinal tumors
- Prostate cancer
- Lung cancer
- Liver cancer
- Pancreatic cancer
- Spinal tumors
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stony Brook University
Lead Sponsor