Tussigon

Acute Bronchitis, Pain, Chronic Pain + 10 more
Treatment
2 FDA approvals
20 Active Studies for Tussigon

What is Tussigon

HydrocodoneThe Generic name of this drug
Treatment SummaryHydrocodone is an opioid medication used to treat moderate to severe pain. It is usually combined with acetaminophen for this purpose. In the past, hydrocodone was used as a cough suppressant, but it has mostly been replaced by a different drug called dextromethorphan. A more powerful form of hydrocodone, called hydromorphone, is used to treat severe pain. The FDA first approved hydrocodone in 1943 as part of a cough suppressant syrup called Hycodan.
Hycodanis the brand name
image of different drug pills on a surface
Tussigon Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hycodan
Hydrocodone
1943
1122

Approved as Treatment by the FDA

Hydrocodone, otherwise called Hycodan, is approved by the FDA for 2 uses including Pain and Pain .
Pain
Used to treat Severe Pain in combination with Acetaminophen
Pain
Helps manage moderate Pain

Effectiveness

How Tussigon Affects PatientsHydrocodone is a drug that helps to block pain signals from reaching the brain and spinal cord. It can also cause a sense of pleasure, slower breathing, and drowsiness.
How Tussigon works in the bodyHydrocodone works by blocking pain signals in the spinal cord and brain. It binds to two different opioid receptors, the mu and delta receptors, with the mu receptor being most important for pain relief. Once bound, it prevents the release of neurotransmitters in the spinal cord and stops certain nerve cells from being activated. In the brain, it stops a GABAergic tone in the periaquaductal gray area, which suppresses pain signals. It can also activate reward and addiction pathways. Finally, it causes a decrease in activity of certain calcium channels, which contributes to pain relief and respiratory depression.

When to interrupt dosage

The prescribed dosage of Tussigon is contingent upon the identified condition, such as Coughing, Coughing and Chronic Pain. The measure of dosage varies as per the mode of administration (e.g. Tablet, extended release - Oral or Tablet - Oral) presented in the table beneath.
Condition
Dosage
Administration
Rhinitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Inflammation
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Allergic rhinitis (disorder)
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Coughing
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Chronic Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Coughing
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Acute Bronchitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Nasal Congestion caused by Allergic Rhinitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
upper respiratory symptoms caused by Common Cold
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Nasal Congestion caused by Common Cold
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Acute Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Warnings

Tussigon has twenty-one recognized contraindications, and should not be administered alongside any of the conditions shown in the following table.Tussigon Contraindications
Condition
Risk Level
Notes
Paralytic Ileus
Do Not Combine
Asthma
Do Not Combine
Intracranial Hypertension
Do Not Combine
Status Asthmaticus
Do Not Combine
in the absence of resuscitative equipment acute bronchial asthma
Do Not Combine
increased cerebrospinal pressure
Do Not Combine
Mental Depression
Do Not Combine
Cor Pulmonale
Do Not Combine
Abdomen
Do Not Combine
convulsive disorders
Do Not Combine
chronic obstructive airway
Do Not Combine
ethanol
Do Not Combine
Gastrointestinal obstruction
Do Not Combine
Alcohol Withdrawal Delirium
Do Not Combine
Asthma
Do Not Combine
Hypercarbia
Do Not Combine
Asthma
Do Not Combine
severe CNS depression
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Hydrocodone may interact with Pulse Frequency
There are 20 known major drug interactions with Tussigon.
Common Tussigon Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Hydrocodone.
Azelastine
Major
Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Hydrocodone.
Eluxadoline
Major
The risk or severity of constipation can be increased when Hydrocodone is combined with Eluxadoline.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Hydrocodone.
Tussigon Toxicity & Overdose RiskOverdosing on hydrocodone can cause drowsiness, shallow breathing, cold and clammy skin, small pupils, fluid in the lungs, slow heartbeat, low blood pressure, and in extreme cases, death. To treat an overdose, it is important to keep the airway clear and provide assistance with breathing if necessary. Other treatments may involve IV fluids, oxygen, or medicines to increase blood pressure. In some cases, a medicine like naloxone can be used to reverse the effects of hydrocodone, but medical monitoring is still necessary as the effects may return. Naloxone can also cause withdrawal symptoms

Tussigon Novel Uses: Which Conditions Have a Clinical Trial Featuring Tussigon?

50 active clinical trials are currently examining the potential of Tussigon to alleviate Chronic Pain, Nasal Congestion caused by Common Cold and Acute Bronchitis.
Condition
Clinical Trials
Trial Phases
Coughing
0 Actively Recruiting
Acute Bronchitis
12 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1
Allergic rhinitis (disorder)
0 Actively Recruiting
Pain
0 Actively Recruiting
Pain
0 Actively Recruiting
Rhinitis
0 Actively Recruiting
Nasal Congestion caused by Allergic Rhinitis
0 Actively Recruiting
Coughing
0 Actively Recruiting
Chronic Pain
31 Actively Recruiting
Phase 2, Not Applicable, Phase 3
upper respiratory symptoms caused by Common Cold
0 Actively Recruiting
Nasal Congestion caused by Common Cold
0 Actively Recruiting
Inflammation
0 Actively Recruiting
Acute Pain
21 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4, Phase 2, Phase 1

Tussigon Reviews: What are patients saying about Tussigon?

5Patient Review
3/23/2009
Tussigon for Cough
This cough syrup is excellent. Not only does it work quickly, but it also tastes great and doesn't leave a nasty aftertaste. I would definitely recommend it to anyone looking for a good quality cough medicine.
5Patient Review
1/20/2009
Tussigon for Cough
4.3Patient Review
8/29/2014
Tussigon for Cough
This medicine is effective.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about tussigon

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can you get high on Tussigon?

"Tussigon contains hydrocodone, which is a substance that has a high potential for abuse and is similar to other opioids such as morphine and codeine."

Answered by AI

Is Tussigon an opioid?

"Tussigon is a prescription medication used to relieve dry coughs by containing two active drugs, hydrocodone and cough suppressant. Hydrocodone works to treat moderate to severe pain and, in Tussigon, stops the urge to cough."

Answered by AI

What is the drug Tussigon used for?

"Tussigon Tablets are a combination of a narcotic cough medicine and a medicine that works against the narcotic to prevent an overdose. They are used to treat cough."

Answered by AI

What is another name for Tussigon?

"Homatropine is an anticholinergic drug, typically used for short-term treatment."

Answered by AI

Clinical Trials for Tussigon

Have you considered Tussigon clinical trials? We made a collection of clinical trials featuring Tussigon, we think they might fit your search criteria.
Have you considered Tussigon clinical trials? We made a collection of clinical trials featuring Tussigon, we think they might fit your search criteria.
Have you considered Tussigon clinical trials? We made a collection of clinical trials featuring Tussigon, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top