What is Trimethoprim
TrimethoprimThe Generic name of this drug
Treatment SummaryTrimethoprim is an antibiotic used to fight bacterial infections. It works by decreasing the production of a certain enzyme in bacteria which stops them from making DNA and surviving. Trimethoprim is often used together with another antibiotic called sulfamethoxazole, but it can also be used alone to treat and prevent urinary tract infections. It has a similar structure and chemical makeup to another medication called pyrimethamine which is used to treat malaria.
Septrais the brand name
Trimethoprim Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Septra
Trimethoprim
1973
340
Approved as Treatment by the FDA
Trimethoprim, also called Septra, is approved by the FDA for 15 uses including susceptible Enteritis infectious caused by Shigella sonnei and Otitis Media .susceptible Enteritis infectious caused by Shigella sonnei
Used to treat susceptible Enteritis infectious caused by Shigella sonnei in combination with Sulfamethoxazole
Otitis Media
Used to treat Acute Otitis Media caused by susceptible bacteria in combination with Sulfamethoxazole
Electrolyte replacement
Used to treat Electrolyte replacement in combination with Sulfamethoxazole
Pneumocystis Jirovecii Pneumonia
Used to treat Pneumocystis Jirovecii Pneumonia in combination with Sulfamethoxazole
Urinary tract infection
Used to treat Urinary Tract Infection caused by susceptible bacteria in combination with Sulfamethoxazole
Immunocompromised
Used to treat Immunocompromised in combination with Sulfamethoxazole
Genus Pneumocystis
Used to treat risk of Pneumocystis jiroveci pneumonia (PCP) in combination with Sulfamethoxazole
Shigellosis
Used to treat Dysentery, Bacillary in combination with Sulfamethoxazole
Cholera
Used to treat susceptible Cholera in combination with Sulfamethoxazole
Nocardiosis
Used to treat Nocardiosis in combination with Sulfamethoxazole
Brucellosis
Used to treat Brucellosis in combination with Rifampicin
Bronchitis
Used to treat Acute Exacerbation of Chronic Bronchitis (AECB) caused by susceptible bacteria in combination with Sulfamethoxazole
Diarrhea
Used to treat susceptible Travelers' Diarrhea caused by Enterotoxigenic E. Coli (ETEC) Infection in combination with Sulfamethoxazole
Fluid replacement therapy
Used to treat Fluid replacement therapy in combination with Sulfamethoxazole
susceptible Enteritis infectious caused by Shigella flexneri
Used to treat susceptible Enteritis infectious caused by Shigella flexneri in combination with Sulfamethoxazole
Effectiveness
How Trimethoprim Affects PatientsTrimethoprim works by blocking an essential step in bacteria’s ability to make proteins and genetic material. It is effective against some types of bacteria, although some may develop resistance to it. Rarely, it can cause blood disorders such as low platelet and white blood cell counts. If you experience symptoms like sore throat, fever, pale skin, and bruising, be sure to tell your doctor right away. Before taking trimethoprim, it’s important to consult local antibiotic sensitivity testing to make sure it will be effective against the bacteria causing your infection.
How Trimethoprim works in the bodyTrimethoprim stops bacteria from making the proteins and genetic material they need to survive. It does this by blocking the action of an enzyme that helps create a molecule necessary for bacterial growth. Trimethoprim is usually given with another drug, sulfamethoxazole, which blocks the step before trimethoprim in bacterial protein synthesis. Together, these two drugs stop bacteria from creating the proteins and genetic material they need to live. When taken alone, trimethoprim only slows down bacteria; but when taken with sulfamethoxazole, it kills them.
When to interrupt dosage
The recommended measure of Trimethoprim is contingent upon the diagnosed disorder, such as Urinary tract infection, Immunocompromised and Pneumocystis Jirovecii Pneumonia. The amount of dosage fluctuates, as per the technique of delivery (e.g. Tablet - Oral or Tablet) detailed in the subsequent table.Condition
Dosage
Administration
Brucellosis
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Otitis Media
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
susceptible Enteritis infectious caused by Shigella sonnei
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Genus Pneumocystis
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Bronchitis
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Cholera
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Pneumocystis Jirovecii Pneumonia
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
bacterial blepharitis caused by susceptible bacteria
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Diarrhea
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Fluid replacement therapy
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Electrolyte replacement
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Immunocompromised
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Urinary tract infection
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Urinary tract infection
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Bacterial conjunctivitis
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Nocardiosis
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Blepharoconjunctivitis caused by susceptible bacteria
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
susceptible Enteritis infectious caused by Shigella flexneri
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Shigellosis
, 40.0 mg, 1.0 mg/mL, 9.0 mg/mL, 16.0 mg/mL, 100.0 mg, 8.0 mg/mL, 80.0 mg, 40.0 mg/mL, 0.16 mg, 1.6 mg, 160.0 mg, 50.0 mg/mL, 20.0 mg, 200.0 mg, 90.0 mg, 300.0 mg
Tablet - Oral, Tablet, Liquid - Intravenous, Solution - Ophthalmic, , Oral, Injection - Intravenous, Ophthalmic, Solution / drops - Ophthalmic, Solution - Oral, Solution / drops, Liquid - Ophthalmic, Injection, solution, concentrate, Suspension - Oral, Solution, Suspension, Liquid, Intravenous, Solution - Intravenous, Injection, Injection, solution, concentrate - Intravenous
Warnings
Trimethoprim has eight contraindications and should not be used when viewing any of the conditions in the subsequent table.Trimethoprim ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Trimethoprim may interact with Toxoplasma Infections
unable to monitor renal function
Do Not Combine
Disease
Do Not Combine
hepatic damage
Do Not Combine
Megaloblastic anemia caused by Folate deficiency
Do Not Combine
history of immune thrombocytopenia caused by trimethoprim and/or sulfonamide therapy
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Trimethoprim may interact with Toxoplasma Infections
Common Trimethoprim Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The excretion of Abemaciclib can be decreased when combined with Trimethoprim.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Trimethoprim.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Trimethoprim.
Cisplatin
Major
The serum concentration of Cisplatin can be increased when it is combined with Trimethoprim.
Clofarabine
Major
The serum concentration of Clofarabine can be increased when it is combined with Trimethoprim.
Trimethoprim Toxicity & Overdose RiskThe lowest toxic dose of trimethoprim in mice and rats is 2764mg/kg and greater than 5300mg/kg respectively. Symptoms of an overdose may include nausea, vomiting, dizziness, headaches, mental depression, confusion, and a decrease in bone marrow production. Treatment should involve supportive care, and the stomach may need to be flushed out with lavage. Increasing the acidity of the urine may help the body eliminate trimethoprim more quickly. Dialysis may help remove some of the drug, but it is only moderately effective.
Trimethoprim Novel Uses: Which Conditions Have a Clinical Trial Featuring Trimethoprim?
8 active trials are currently taking place to investigate the possible application of Trimethoprim to treat Shigella flexneri-induced Enteritis, Bacterial-induced Blepharoconjunctivitis and Diarrhea.Condition
Clinical Trials
Trial Phases
Diarrhea
0 Actively Recruiting
Fluid replacement therapy
0 Actively Recruiting
Blepharoconjunctivitis caused by susceptible bacteria
0 Actively Recruiting
susceptible Enteritis infectious caused by Shigella flexneri
0 Actively Recruiting
Immunocompromised
2 Actively Recruiting
Phase 1, Phase 3
Bronchitis
0 Actively Recruiting
Brucellosis
0 Actively Recruiting
Pneumocystis Jirovecii Pneumonia
1 Actively Recruiting
Phase 3
susceptible Enteritis infectious caused by Shigella sonnei
0 Actively Recruiting
bacterial blepharitis caused by susceptible bacteria
0 Actively Recruiting
Electrolyte replacement
0 Actively Recruiting
Nocardiosis
0 Actively Recruiting
Shigellosis
4 Actively Recruiting
Phase 2, Phase 1
Urinary tract infection
0 Actively Recruiting
Otitis Media
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting
Cholera
0 Actively Recruiting
Bacterial conjunctivitis
0 Actively Recruiting
Genus Pneumocystis
0 Actively Recruiting
Trimethoprim Reviews: What are patients saying about Trimethoprim?
5Patient Review
2/10/2014 I take it just once a day to keep things working properly. The only downside is that I sometimes experience a lot of gas.
5Patient Review
3/1/2014 Blood and cloudy urine cleared up within a week of taking this medication, as directed. No bacteria was found on the culture. Does cause gas; however, probiotics seemed to help with that issue.
5Patient Review
2/19/2019 I've been using this treatment for six months now and I haven't had a UTI in that entire time. Prior to this, I was getting them every few month; some days were even really bad.
5Patient Review
8/28/2019 I didn't have any negative reactions, which was great.
4.7Patient Review
4/28/2014 I've been taking this for four months now to prevent UTIs. I generally take it before bed. Recently, I developed a rash on my neck that's been pretty itch and won't go away no matter what I do. It might be from sun exposure, so I'm going to stop taking the medication and hope that the rash goes away and that I don't get a UTI again.
4.3Patient Review
12/5/2013 I was put on this medication after having four UTIs in three months. It's been four months since then and I haven't had another infection, which is amazing. I'll probably be on this medication for the rest of my life.
4.3Patient Review
4/6/2016 The drug did clear up the infection, but I found it hard to take because it started dissolving quickly and often stuck to the back of my tongue.
4.3Patient Review
9/21/2017 This chronic UTI treatment helps to prevent breakthrough infections for patients who have to self-catheterize regularly.
3Patient Review
1/8/2014 I'm on my second day of treatment, and I feel faint every hour. I also can't keep food down, and my kidneys are still hurting. Additionally, there's a burning sensation in my belly and I feel dizzy.
3Patient Review
7/15/2015 The tablets cleared the infection, but I felt awful afterward. Total fatigue and some nausea. I stopped taking them after five days and felt much better immediately.
1.7Patient Review
8/11/2022 These antibiotics were an awful experience for me. I started having burning and spasms in my vagina, then severe lower abdominal pain. I ended up vomiting 20 times and had to go to the emergency room. Since then, I've been constantly in pain and have had bladder pressure.
1Patient Review
7/4/2013 I had a severe allergic reaction to this medication and now have to wear an allergy bracelet. Just half a tablet caused my mouth to swell so much that I couldn't eat, and I also suffered from extreme itching in personal areas. It took a week of large doses of steroids for me to start feeling any relief.
1Patient Review
9/12/2019 I've been on so many antibiotics at this point and they all make me feel terrible. I get nauseous, shaky, and my heart races. This last one prescribed by the doctor didn't even help with the nausea.
1Patient Review
3/1/2019 Almost immediately after starting this medication, I began to experience heart palpitations and irregular heartbeat. When I called my GP about it, he brushed me off and said it wasn't possible. Even though that's a listed side effect on the bottle! Irregular heartbeat is even more common than a simple headache. So not only am I in pain, but now I'm also terrified and exhausted from lack of sleep. Cannot wait for this poison to leave my system.
1Patient Review
9/7/2018 I had an allergic reaction to this medication and it caused me to break out in red blotches all over my body.
Patient Q&A Section about trimethoprim
What kind of antibiotic is trimethoprim?
"It is an antibiotic that helps to treat infections and is often used in combination with another medication." - Anonymous Online Contributor
Unverified Answer
What are the common side effects of trimethoprim?
"Diarrhea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache may occur. If you experience any of these effects for an extended period of time, or if they worsen, tell your doctor or pharmacist." - Anonymous Online Contributor
Unverified Answer
How long does it take for trimethoprim to work for urinary tract infection?
"If you take trimethoprim and your symptoms do not improve within 48 hours, you should see a doctor." - Anonymous Online Contributor
Unverified Answer
What is the drug trimethoprim used for?
"It comes as tablets. Trimethoprim is an antibiotic. It is used to treat and prevent urinary tract infections (UTIs), such as cystitis. Occasionally, trimethoprim is used to treat other types of infections, such as chest infections and acne. Trimethoprim is available on prescription. It comes as tablets." - Anonymous Online Contributor
Unverified Answer