Trilipix

Primary Hypercholesterolemia, Diet, Hypertriglyceridemia + 2 more
Treatment
16 Active Studies for Trilipix

What is Trilipix

Fenofibric acidThe Generic name of this drug
Treatment SummaryFenofibric acid is a medication used to lower dangerous levels of cholesterol and triglycerides. It helps to lower bad cholesterol (low-density lipoprotein cholesterol) while raising good cholesterol (high-density lipoprotein cholesterol). Fenofibric acid is not well absorbed by the body, so it is usually given as a prodrug or a conjugated compound to help it be more easily absorbed and more effective.
Fenofibric Acidis the brand name
image of different drug pills on a surface
Trilipix Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fenofibric Acid
Fenofibric acid
2008
66

Effectiveness

How Trilipix Affects PatientsStudies have linked high levels of total cholesterol, LDL (low-density-lipoprotein), and apolipoprotein B (a type of LDL) to atherosclerosis. Low levels of HDL (high-density-lipoprotein) and its transport complex (apolipoproteins apo AI and apo AII) have also been linked to atherosclerosis. Additionally, research suggests that cardiovascular problems and death risk increase with higher levels of total cholesterol, LDL, and triglycerides, but decrease with higher levels of HDL.Fenofibric acid, a metabolite of fenofibrate,
How Trilipix works in the bodyFenofibric acid helps reduce triglycerides and increase good cholesterol in the body. It does this by activating a receptor in the body called PPAR-alpha. This leads to an increase in lipolysis, which is the breakdown of fat. It also causes low-density-lipoprotein particles to become larger and more easily broken down by the body. Fenofibric acid also increases production of apoproteins A-I and A-II, which are proteins that help transport fats in the blood. Lastly, it can help reduce uric acid levels in the body by increasing the amount of uric acid excret

When to interrupt dosage

The advised dosage of Trilipix is contingent upon the diagnosed disorder, including Hypertriglyceridemias, Primary Hypercholesterolemia and Diet. The amount of dosage is contingent on the delivery approach (e.g. Capsule, delayed release - Oral or Oral) as depicted in the following table.
Condition
Dosage
Administration
Primary Hypercholesterolemia
, 45.0 mg, 135.0 mg, 35.0 mg, 105.0 mg
, Oral, Capsule, delayed release, Capsule, delayed release - Oral, Tablet, Tablet - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral
Diet
, 45.0 mg, 135.0 mg, 35.0 mg, 105.0 mg
, Oral, Capsule, delayed release, Capsule, delayed release - Oral, Tablet, Tablet - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral
Hypertriglyceridemia
, 45.0 mg, 135.0 mg, 35.0 mg, 105.0 mg
, Oral, Capsule, delayed release, Capsule, delayed release - Oral, Tablet, Tablet - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral
Triglycerides
, 45.0 mg, 135.0 mg, 35.0 mg, 105.0 mg
, Oral, Capsule, delayed release, Capsule, delayed release - Oral, Tablet, Tablet - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral
Dyslipidemias
, 45.0 mg, 135.0 mg, 35.0 mg, 105.0 mg
, Oral, Capsule, delayed release, Capsule, delayed release - Oral, Tablet, Tablet - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral

Warnings

Trilipix has five contraindications. It should not be employed in combination with the conditions specified in the following table.Trilipix Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Fenofibric Acid may interact with Pulse Frequency
Liver Diseases
Do Not Combine
Renal Insufficiency
Do Not Combine
Disease
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Fenofibric Acid may interact with Pulse Frequency
There are 20 known major drug interactions with Trilipix.
Common Trilipix Drug Interactions
Drug Name
Risk Level
Description
Albutrepenonacog alfa
Minor
Fenofibric acid may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Bismuth subgallate
Minor
Fenofibric acid may decrease the excretion rate of Bismuth subgallate which could result in a higher serum level.
Choline salicylate
Minor
Fenofibric acid may decrease the excretion rate of Choline salicylate which could result in a higher serum level.
Chromic citrate
Minor
Fenofibric acid may decrease the excretion rate of Chromic citrate which could result in a higher serum level.
Chromic nitrate
Minor
Fenofibric acid may decrease the excretion rate of Chromic nitrate which could result in a higher serum level.

Trilipix Novel Uses: Which Conditions Have a Clinical Trial Featuring Trilipix?

14 active clinical trials are currently assessing the potential of Trilipix in ameliorating Dyslipidemias, Triglycerides and Dietary-related issues.
Condition
Clinical Trials
Trial Phases
Triglycerides
0 Actively Recruiting
Primary Hypercholesterolemia
10 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Dyslipidemias
1 Actively Recruiting
Phase 2
Hypertriglyceridemia
0 Actively Recruiting
Diet
5 Actively Recruiting
Not Applicable, Phase 1

Trilipix Reviews: What are patients saying about Trilipix?

5Patient Review
6/12/2012
Trilipix for High Amount of Triglyceride in the Blood
I developed a dry mouth and tongue around the same time. Wearing dentures becomes painful when my mouth gets too dry.
5Patient Review
4/18/2013
Trilipix for Combined High Blood Cholesterol and Triglyceride Level
I've been using this treatment for two years and have seen a significant drop in my cholesterol levels. My HDL is down to 30, LDL 61, and TRIGLYCERIDES have gone from over 300 to 82. I take it with breakfast every day and don't notice any negative side effects.
5Patient Review
1/18/2014
Trilipix for Combined High Blood Cholesterol and Triglyceride Level
I take this medicine in conjunction with Lipitor. While Lipitor lowered my triglyceride and LDL levels, it didn't increase my HDL levels. However, the combination of the two medications did the trick. I'm 5'8" and 142lbs, I exercise regularly and watch what I eat--but these lifestyle choices alone weren't enough. The only side effect I experienced was some muscle problems, but they were tolerable.
5Patient Review
10/14/2013
Trilipix for High Cholesterol
I had zero of the bad reactions that other people have described. In fact, my LDL (low-density lipoprotein) went down and HDL (high-density lipoprotein) up. The only issue I had was with the cost, but I've since switched to the generic version and it's working just as well.
4Patient Review
1/6/2012
Trilipix for Combined High Blood Cholesterol and Triglyceride Level
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about trilipix

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of TRILIPIX?

"The possible side effects of the medication are nausea, an upset stomach, headaches, dizziness, back pain, joint pain, or cold symptoms such as a stuffy nose, sneezing, or a sore throat."

Answered by AI

What is TRILIPIX used for?

"TRILIPIX is a prescription medicine used to lower the total amount of triglycerides and LDL (bad) cholesterol in the blood, and increase the HDL (good) cholesterol. You should be on a low fat and low cholesterol diet while you take TRILIPIX."

Answered by AI

Is there a generic for TRILIPIX?

"If you are taking Tricor, Trilipix, or the generic fenofibrate, you should be aware of what has happened. Abbott Laboratories used this strategy to avoid generic competition for its branded formulations of fenofibrate."

Answered by AI

Is TRILIPIX a statin drug?

"Zocor is a statin drug, while Trilipix is a lipid regulating agent."

Answered by AI

Clinical Trials for Trilipix

Have you considered Trilipix clinical trials? We made a collection of clinical trials featuring Trilipix, we think they might fit your search criteria.
Have you considered Trilipix clinical trials? We made a collection of clinical trials featuring Trilipix, we think they might fit your search criteria.
Have you considered Trilipix clinical trials? We made a collection of clinical trials featuring Trilipix, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top