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What is Tri-Luma
HydroquinoneThe Generic name of this drug
Treatment SummaryHydroquinone is a skin-lightening product found in some over-the-counter products. It is used to treat discoloration on the skin caused by melasma, freckles, sunspots, and other conditions. It is often combined with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen. However, due to possible side effects such as irritation, discoloration, and carcinogenicity, hydroquinone has been banned in the EU and UK.
Ultra Glow Fade with Aloe Verais the brand name
Tri-Luma Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ultra Glow Fade with Aloe Vera
Hydroquinone
1964
1
Approved as Treatment by the FDA
Hydroquinone, commonly known as Ultra Glow Fade with Aloe Vera, is approved by the FDA for 3 uses including Chloasma and Chloasma .Chloasma
Used to treat moderate Melasma in combination with Fluocinolone acetonide
Chloasma
Used to treat severe Melasma in combination with Fluocinolone acetonide
Melasma
Effectiveness
How Tri-Luma works in the bodyHydroquinone lightens skin by blocking the enzyme that produces melanin pigment. This process takes several months to take effect.
When to interrupt dosage
The prescribed measure of Tri-Luma is reliant upon the designated malady, such as Chloasma, Chloasma and Melasma. The amount likewise fluctuates in relation to the mode of delivery, featured in the table beneath.Condition
Dosage
Administration
Melasma
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Aging
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Sun Exposure
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Solar Elastosis
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Chloasma
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Acne Vulgaris
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Hormone Disturbance
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Chloasma
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Skin
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Hyperpigmentation
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Warnings
Tri-Luma ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Tri-Luma Drug Interactions
Drug Name
Risk Level
Description
Tri-Luma Novel Uses: Which Conditions Have a Clinical Trial Featuring Tri-Luma?
176 active clinical trials are currently exploring the potential of Tri-Luma to alleviate Melasma, Solar Elastosis and Acne.Condition
Clinical Trials
Trial Phases
Acne Vulgaris
22 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3
Aging
150 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 1, Phase 3, Phase 4
Sun Exposure
0 Actively Recruiting
Chloasma
0 Actively Recruiting
Chloasma
0 Actively Recruiting
Solar Elastosis
8 Actively Recruiting
Phase 1, Phase 2, Phase 4, Not Applicable
Skin
0 Actively Recruiting
Hyperpigmentation
0 Actively Recruiting
Hormone Disturbance
1 Actively Recruiting
Phase 1
Melasma
0 Actively Recruiting
Tri-Luma Reviews: What are patients saying about Tri-Luma?
5Patient Review
9/6/2013 This cream was on the pricey side, but it delivered great results. I started peeling a little and my face felt a little sensitive like there was a mild burning sensation but nothing too drastic.
5Patient Review
4/28/2015 I'm so happy I decided to go to the dermatologist and figure out what was going on with my face. In just four weeks, this product has given me back my confidence. I can't believe how well it works! Thank you so much for developing this amazing treatment.
5Patient Review
11/5/2015 Tri Luma was able to effectively clear up my melasma in just two months. I'm now confident enough to go without makeup entirely.
5Patient Review
7/7/2014 This stuff is amazing and works exactly as advertised. In a few weeks, my sunspots were totally gone. I highly recommend this to anyone with facial discoloration issues.
5Patient Review
8/1/2015 Tri-Luma has been a total lifesaver for me. I had gotten to the point where I was really self-conscious about the melasma on my upper lip, but this cream has made such a difference in just a couple of weeks. I can almost go makeup-free now, and there's no irritation or side effects that I've noticed.
3Patient Review
9/25/2013 I used this cream on and off for a year. While it did help with my melasma, it also made my skin very red and thin. I stopped using it and the melasma came back immediately. This is not a permanent cure; don't use it long term because of the bad side effects.
3Patient Review
4/21/2018 I'm an older woman with melasma on my forehead. I had given up hope that anything could improve the condition, but this treatment has shown some promise in just a week of use. There's still more progress to be made, but I'm cautiously optimistic.
2.3Patient Review
12/30/2013 I am a medium complexion African American female. I started using this product six months ago to target brown spots, but they have actually gotten larger since then. Needless to say, I'll be discontinuing use and consulting my dermatologist for other options.
2Patient Review
12/13/2015 Triluma was effective for my melasma in the short term, but unfortunately it came back even darker once I stopped using the treatment.
1.7Patient Review
12/30/2017 I would not recommend this treatment to anyone. Not only is it expensive, but it also made my skin red and irritated. I followed the instructions to a T, and after two months of use, I can say with certainty that this cream does nothing but burn your skin. Folic acid is a much cheaper and more effective alternative.
1.3Patient Review
9/22/2016 I used this product for seven weeks as directed, and saw no change in the skin above my upper lip. very disappointed, especially given the high cost of the treatment.
1Patient Review
11/23/2014 At first, this product lightened my dark spots significantly. However, as soon as I stopped using it, the brown spots not only returned but were darker than before.
1Patient Review
4/24/2022 I was very disappointed with this treatment. I followed the doctor's orders perfectly, but instead of getting better, my condition got much worse. Now I have to wear makeup to cover up the dark patches on my forehead that this treatment caused.
Patient Q&A Section about tri-luma
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of Tri-Luma?
"You may experience a mild burning, stinging, redness, dryness, tingling, itching, swelling, or peeling of your skin. You may also develop a rash, acne, or skin bumps or blisters."
Answered by AI
Is Tri-Luma the same as hydroquinone?
"The medication Fluocinolone/Tretinoin/Hydroquinone is sold under the brand name Tri-Luma."
Answered by AI
How long does it take for Tri-Luma to work?
"Although you may not see significant improvement for up to 4 weeks, this medication is not recommended for long-term use without taking breaks. If your condition does not improve after 4 weeks of treatment, inform your doctor."
Answered by AI
What is TRI-LUMA Cream good for?
"Hydroquinone 4% is a skin-lightening agent that inhibits melanin production. Tretinoin 0.05% is a retinoid that promotes skin cell turnover and clears plugged hair follicles.
Tri-Luma® Cream is a unique triple-combination topical therapy that is used for the short-term treatment of dark spots that are associated with moderate to severe facial melasma. Fluocinolone acetonide 0.01% is a mild corticosteroid that helps to reduce inflammation. Hydroquinone 4% is a skin-lightening agent that inhibits melanin production. Tretinoin 0.05% is a retinoid that promotes skin cell turnover and clears plugged hair follicles."
Answered by AI