Tri-Luma

Hyperpigmentation, Melanosis, Chloasma + 7 more
Treatment
5 FDA approvals
20 Active Studies for Tri-Luma

What is Tri-Luma

HydroquinoneThe Generic name of this drug
Treatment SummaryHydroquinone is a skin-lightening product found in some over-the-counter products. It is used to treat discoloration on the skin caused by melasma, freckles, sunspots, and other conditions. It is often combined with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen. However, due to possible side effects such as irritation, discoloration, and carcinogenicity, hydroquinone has been banned in the EU and UK.
Ultra Glow Fade with Aloe Verais the brand name
image of different drug pills on a surface
Tri-Luma Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ultra Glow Fade with Aloe Vera
Hydroquinone
1964
1

Approved as Treatment by the FDA

Hydroquinone, commonly known as Ultra Glow Fade with Aloe Vera, is approved by the FDA for 5 uses including Chloasma and Chloasma .
Chloasma
Used to treat severe Melasma in combination with Fluocinolone acetonide
Chloasma
Used to treat moderate Melasma in combination with Fluocinolone acetonide
severe Melasma
Used to treat severe Melasma in combination with Fluocinolone acetonide
moderate Melasma
Used to treat moderate Melasma in combination with Fluocinolone acetonide
Melanosis

Effectiveness

How Tri-Luma works in the bodyHydroquinone lightens skin by blocking the enzyme that produces melanin pigment. This process takes several months to take effect.

When to interrupt dosage

The prescribed measure of Tri-Luma is reliant upon the designated malady, such as Chloasma, Chloasma and Melasma. The amount likewise fluctuates in relation to the mode of delivery, featured in the table beneath.
Condition
Dosage
Administration
Hyperpigmentation
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Chloasma
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Chloasma
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Aging
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Sunburn
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Melanosis
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Acne Vulgaris
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Solar Elastosis
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Skin
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical
Hormone Disturbance
0.02 mg/mg, , 0.04 mg/mg, 0.02 mg/mL, 20.0 mg/mL, 0.02 mL/mL, 0.12 mL/mL, 0.0946 mg/mL, 0.1 mg/mg, 0.2 mg/mg, 30.0 mg/mL, 40.0 mg/mL, 0.01695 mg/mg, 0.06 mg/mg, 0.1 mL/mL, 0.104 mL/mL, 0.04 mL/mL, 0.05 mL/mL, 0.019 mg/mg, 40000.0 mg/mL, 0.12 mg/mg, 2.0 %, 4.0 %, 0.114 mg/mg, 1.8 %, 1.5 %, 200.0 mg/mL, 0.00002 mg/mg, 100.0 mg/mL, 0.08 mg/mg, 0.05 mg/mg, 0.05 mg/mL, 0.015 mg/mg, 100.0 mg/mg, 0.03 mg/mg, 0.075 mg/mg, 0.04 mg/mL, 0.004 mg/mg, 2.0 mg/mg, 0.08 mg/mL, 20.0 mg, 20000.0 mg/mL, 80.0 mg/mL, 0.0002 mg/mL, 57.0 mg/mL, 76.0 mg/mL, 50.0 mg/mL, 95.0 mg/mL, 0.0012 mg/mg, 0.0006 mg/mg
, Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Liquid - Topical, Liquid, Kit, Gel, Gel - Topical, Emulsion, Emulsion - Topical, Cutaneous, Cream - Cutaneous, Lotion - Cutaneous, Cloth, Cloth - Topical, Solution, Solution - Topical, Kit - Topical

Warnings

Tri-Luma Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Tri-Luma Drug Interactions
Drug Name
Risk Level
Description
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Tri-Luma Novel Uses: Which Conditions Have a Clinical Trial Featuring Tri-Luma?

176 active clinical trials are currently exploring the potential of Tri-Luma to alleviate Melasma, Solar Elastosis and Acne.
Condition
Clinical Trials
Trial Phases
Skin
0 Actively Recruiting
Hyperpigmentation
0 Actively Recruiting
Chloasma
0 Actively Recruiting
Melanosis
0 Actively Recruiting
Chloasma
0 Actively Recruiting
Solar Elastosis
4 Actively Recruiting
Phase 1, Phase 2, Not Applicable
Sunburn
0 Actively Recruiting
Hormone Disturbance
1 Actively Recruiting
Phase 1
Acne Vulgaris
9 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4
Aging
157 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 3, Phase 1, Phase 4

Tri-Luma Reviews: What are patients saying about Tri-Luma?

5Patient Review
9/6/2013
Tri-Luma for Yellow-Brown Patches on Skin
This cream was on the pricey side, but it delivered great results. I started peeling a little and my face felt a little sensitive like there was a mild burning sensation but nothing too drastic.
5Patient Review
4/28/2015
Tri-Luma for Yellow-Brown Patches on Skin
I'm so happy I decided to go to the dermatologist and figure out what was going on with my face. In just four weeks, this product has given me back my confidence. I can't believe how well it works! Thank you so much for developing this amazing treatment.
5Patient Review
11/5/2015
Tri-Luma for Yellow-Brown Patches on Skin
Tri Luma was able to effectively clear up my melasma in just two months. I'm now confident enough to go without makeup entirely.
5Patient Review
7/7/2014
Tri-Luma for Yellow-Brown Patches on Skin
This stuff is amazing and works exactly as advertised. In a few weeks, my sunspots were totally gone. I highly recommend this to anyone with facial discoloration issues.
5Patient Review
8/1/2015
Tri-Luma for Yellow-Brown Patches on Skin
Tri-Luma has been a total lifesaver for me. I had gotten to the point where I was really self-conscious about the melasma on my upper lip, but this cream has made such a difference in just a couple of weeks. I can almost go makeup-free now, and there's no irritation or side effects that I've noticed.
View All Reviews
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Patient Q&A Section about tri-luma

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of Tri-Luma?

"You may experience a mild burning, stinging, redness, dryness, tingling, itching, swelling, or peeling of your skin. You may also develop a rash, acne, or skin bumps or blisters."

Answered by AI

Is Tri-Luma the same as hydroquinone?

"The medication Fluocinolone/Tretinoin/Hydroquinone is sold under the brand name Tri-Luma."

Answered by AI

How long does it take for Tri-Luma to work?

"Although you may not see significant improvement for up to 4 weeks, this medication is not recommended for long-term use without taking breaks. If your condition does not improve after 4 weeks of treatment, inform your doctor."

Answered by AI

What is TRI-LUMA Cream good for?

"Hydroquinone 4% is a skin-lightening agent that inhibits melanin production. Tretinoin 0.05% is a retinoid that promotes skin cell turnover and clears plugged hair follicles.

Tri-Luma® Cream is a unique triple-combination topical therapy that is used for the short-term treatment of dark spots that are associated with moderate to severe facial melasma. Fluocinolone acetonide 0.01% is a mild corticosteroid that helps to reduce inflammation. Hydroquinone 4% is a skin-lightening agent that inhibits melanin production. Tretinoin 0.05% is a retinoid that promotes skin cell turnover and clears plugged hair follicles."

Answered by AI

Clinical Trials for Tri-Luma

Have you considered Tri-Luma clinical trials? We made a collection of clinical trials featuring Tri-Luma, we think they might fit your search criteria.
Have you considered Tri-Luma clinical trials? We made a collection of clinical trials featuring Tri-Luma, we think they might fit your search criteria.
Have you considered Tri-Luma clinical trials? We made a collection of clinical trials featuring Tri-Luma, we think they might fit your search criteria.