Terra-Cortril

Scleritis, Iridocyclitis, Iritis + 47 more

Treatment

22 FDA approvals

20 Active Studies for Terra-Cortril

What is Terra-Cortril

Hydrocortisone acetate

The Generic name of this drug

Cortisporin

is the brand name

Terra-Cortril Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cortisporin

Hydrocortisone acetate

1963

43

Approved as Treatment by the FDA

Hydrocortisone acetate, commonly known as Cortisporin, is approved by the FDA for 22 uses which include Hypersensitivity and Neoplastic Disease .

Hypersensitivity

Neoplastic Disease

Collagen Diseases

Rheumatoid Arthritis

Helps manage Rheumatoid Arthritis

Skin Diseases

Androgenital syndrome

Helps manage Androgenital syndrome

Haemorrhoids

Thyroiditis

Helps manage Thyroiditis

Thyroiditis

Helps manage Thyroiditis

Dermatological Disease

Itching

Ulcerative Colitis

Used in combination with other therapies

Pruritus

hormonal disorder

Proctitis

Helps manage Proctitis

Atopic Dermatitis

Skin Irritation

Adrenal Insufficiency

Helps manage Adrenal cortical hypofunctions

Ulcerative Colitis

Used in combination with other therapies

Adrenal cortical hypofunctions

Helps manage Adrenal cortical hypofunctions

Proctitis

Helps manage Proctitis

cryptitis

Helps manage cryptitis

Effectiveness

How Terra-Cortril Affects Patients

Hydrocortisone is an important steroid hormone in humans that helps regulate a variety of bodily functions, including the immune system and metabolism. It can be used topically to reduce inflammation and suppress the immune response. Glucocorticoids like hydrocortisone work by inhibiting the production of cytokines, which are molecules that regulate the immune response. This reduces the number of activated T cells and B cells, which decreases the body's ability to fight off infections and make antibodies.

How Terra-Cortril works in the body

Hydrocortisone works by binding to the glucocorticoid receptor in the cell nucleus. This stimulates the expression of certain target genes and inhibits the production of arachidonic acid, which is used to create prostaglandins and leukotrienes, two major contributors to inflammation. Hydrocortisone also reduces the activity of both cyclooxygenase enzymes and prevents lipocortin-1 from interacting with cell membranes. This leads to an overall decrease in inflammation, as well as a decrease in the activity of the immune system.

When to interrupt dosage

The proposed measure of Terra-Cortril is dependent upon the determined illness, including Pink Eye, Skin Infections and hormonal imbalance. The quantity of dosage is contingent upon the method of administration shown in the table beneath.

Condition

Dosage

Administration

Acute, Inflammatory Superficial Cutaneous Lesions caused by susceptible bacteria

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Thyroiditis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Itching

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Blepharitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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ocular bacterial infections

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Adrenal Insufficiency

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Communicable Diseases

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Adrenal Cortex Hormones

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Collagen Diseases

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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hormonal disorder

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Ulcerative Colitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Anorectal Surgeries

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Fissure in Ano

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Anal inflammation

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Proctitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Postoperative

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Allergic Conjunctivitis (AC)

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Dermatitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Hemorrhoids

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

Topical, , Aerosol, foam, Aerosol, foam - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Ointment, Ointment - Topical, Kit, Suppository - Rectal, Rectal, Suppository, Cream - Rectal, Gel - Rectal, Gel, Gel - Topical, Aerosol, foam - Rectal, Auricular (otic); Ophthalmic, Ointment - Auricular (otic); Ophthalmic, Suspension - Auricular (otic); Ophthalmic, Suspension, Rectal; Topical, Ointment - Rectal; Topical, Ointment - Rectal, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Aerosol, Aerosol - Rectal, Soap, Soap - Topical, Powder - Topical, Powder, for solution - Topical, Powder, for solution, Powder, Cream - Rectal; Topical, Lotion / shampoo, Lotion / shampoo - Topical, Ointment - Ophthalmic, Shampoo - Topical, Shampoo, Kit - Topical, Solution, Solution - Topical, Auricular (otic), Solution / drops - Auricular (otic), Suspension - Ophthalmic, Suspension - Auricular (otic), Kit - Oral, Oral, Kit - Irrigation; Ophthalmic; Topical, Irrigation; Ophthalmic; Topical, Kit - Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Oral; Rectal, Kit - Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Topical, Kit - Respiratory (inhalation); Topical, Kit - Ophthalmic; Topical, Ophthalmic; Respiratory (inhalation); Topical, Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Respiratory (inhalation); Topical

Androgenital syndrome

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Warnings

There are 20 known major drug interactions with Terra-Cortril.

Common Terra-Cortril Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Hydrocortisone acetate.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Hydrocortisone acetate.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Hydrocortisone acetate.

Alpelisib

Major

The metabolism of Alpelisib can be increased when combined with Hydrocortisone acetate.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Hydrocortisone acetate.

Terra-Cortril Toxicity & Overdose Risk

Taking too much of this drug can lead to weakened bones, reduced calcium absorption, and difficulty healing wounds.

Terra-Cortril Novel Uses: Which Conditions Have a Clinical Trial Featuring Terra-Cortril?

91 active trials are being conducted to assess the efficacy of Terra-Cortril in providing relief and treatment for cryptitis, Ocular and Dermatological conditions.

Condition

Clinical Trials

Trial Phases

Rheumatoid Arthritis

55 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Open-angle glaucoma

45 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 4, Early Phase 1, Phase 1

Thyroiditis

0 Actively Recruiting

Adrenal Insufficiency

0 Actively Recruiting

Fluorophotometry

0 Actively Recruiting

Eczema

0 Actively Recruiting

Ulcerative Colitis

14 Actively Recruiting

Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1

Anorectal Surgeries

0 Actively Recruiting

Defecation

0 Actively Recruiting

Iritis

0 Actively Recruiting

Proctitis

0 Actively Recruiting

Hypersensitivity

1 Actively Recruiting

Phase 4

Allergic Conjunctivitis (AC)

1 Actively Recruiting

Phase 2

Dermatologic disorders

0 Actively Recruiting

Scleritis

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Androgenital syndrome

0 Actively Recruiting

Haemorrhoids

1 Actively Recruiting

Not Applicable

Neoplastic Disease

1 Actively Recruiting

Phase 1

Dermatitis

1 Actively Recruiting

Not Applicable

Patient Q&A Section about terra-cortril

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Terra-Cortril ointment used for?

"Hydrocortisone is a corticosteroid typically used to reduce inflammation of the skin caused by allergies, infection, or injury. In this case, Terra-Cortril ointment has been prescribed by a doctor to treat eczema, which is an inflammatory skin condition."

Answered by AI

How long can you use Terra-Cortril for?

"You can use Terra-Cortril Ointment for up to seven days if you have exudative flexural intertrigo. However, like other tetracyclines, oxytetracycline is not effective against Pseudomonas and Proteus species."

Answered by AI

How do you use Terracortril polymyxin B?

"Put two to four drops of the medicine into the affected ear three times each day."

Answered by AI

Is Terra-Cortril an antibiotic?

"Terra-Cortril is a combination antibiotic and corticosteroid used to treat corticosteroid-responsive inflammatory conditions of the eye and ear that are also infected with organisms that are susceptible to oxytetracycline and/or polymyxin B sulfate."

Answered by AI

Clinical Trials for Terra-Cortril

Image of University Health Network/ Toronto Western Hospital in Toronto, Canada.

Biofeedback Training for Glaucoma

Any Age
All Sexes
Toronto, Canada

This randomized controlled clinical trial evaluates the efficacy of visual biofeedback training on visual function and quality of life in individuals with glaucoma. Glaucoma is a progressive optic neuropathy that can lead to irreversible vision loss, including impaired fixation stability, reduced retinal sensitivity, and decreased functional vision. Biofeedback training is a visual rehabilitation technique designed to help patients improve fixation stability and optimize use of remaining visual function by training eye movements toward retinal areas with better sensitivity. Seventy participants with glaucoma will be randomized to either a biofeedback training intervention group or a control group. Visual function outcomes, including fixation stability, retinal sensitivity, visual acuity, reading speed, contrast sensitivity, and quality of life, will be assessed at baseline and follow-up visits. This study aims to determine whether biofeedback training can improve visual function and quality of life in patients with glaucoma.

Recruiting
Has No Placebo

University Health Network/ Toronto Western Hospital

Image of University Center for Ambulatory Surgery in Somerset, United States.

Infusion Pump for Postoperative Pain

18+
All Sexes
Somerset, NJ

This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period.. Patients 18 years or older undergoing ACL reconstruction, open shoulder labrum or rotator cuff surgery, arthroscopic rotator cuff repair, proximal or distal patellar realignment surgery, open knee arthrotomy cases (i.e. inside out meniscus repair, osteochondral allograft transplantation (OCA), meniscal allograft transplantation (MAT)) at University Center for Ambulatory Surgery, LLC (UOA) will be reviewed for eligibility. Once identified, potential study subjects will be asked whether they are interested in participating in the project. If the patient agrees, the subject will be given the informed consent to read and sign. Objectives: The primary objective is to compare the effectiveness of postoperative infusion pain pump versus preoperative nerve block in reducing visual analog pain scores/numerical pain rating scale (VAS/NPRS) in the postoperative period. The second objective is to evaluate the requirement of narcotic and non-narcotic analgesic medications between the two groups. Hypotheses: Use of continuous infusion pain pump or single shot peripheral block will result in similar post-operative pain control after outpatient sports medicine surgical cases.

Phase 4
Recruiting

University Center for Ambulatory Surgery

Image of University of Waterloo, School of Optometry and Vision Science in Waterloo, Canada.

Brain Stimulation for Vision Impairment

18+
All Sexes
Waterloo, Canada

This pilot clinical trial evaluates whether non-invasive brain stimulation improves the orientation and mobility (O\&M) skills of individuals with constricted visual fields in both eyes. The study is composed of three visits. The first visit is meant to confirm eligibility by performing a few clinical tests. Eligible participants will then complete two additional visits, one in which the participants receive active stimulation, and one in which the participants receive placebo (sham) stimulation. Stimulation will be administered in a randomized, double-blind order. To evaluate improvement, various measures of O\&M performance will be assessed on a standardized obstacle course featuring static natural and artificial obstacles at defined intervals after the intervention. The investigators hypothesize that the application of brain stimulation to region of the brain responsible for visual processing will improve the orientation and mobility skills of individuals with binocular constricted visual fields immediately following stimulation, and the results will inform the design of a future, larger-scale study.

Waitlist Available
Device

University of Waterloo, School of Optometry and Vision Science

Benjamin Thompson, PhD

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Image of Byers Eye Institute in Palo Alto, United States.

LLM-Based Education for Glaucoma

18+
All Sexes
Palo Alto, CA

The purpose of this study is to evaluate whether a large language model (LLM)-based audiovisual educational tool improves the test time and reliability of standard automated perimetry (SAP) using the SITA Standard 24-2 protocol in English-speaking glaucoma patients. Glaucoma is a disease that can lead to blindness if not properly monitored and treated. One of the most important tests for glaucoma is the visual field (VF) test, which checks how well a person can see in different directions. However, this test is difficult for many patients to perform correctly, especially if they don't fully understand how it works. Unreliable test results can lead to repeated visits, wasted time, and incorrect treatment decisions. This study is testing whether a computer-based educational tool, powered by artificial intelligence (AI), can help patients better understand the VF test before taking it. The study team want to see if this helps make the test results more reliable. The goal is to improve the quality of care while reducing the burden on patients and clinic staff. The LLMs will be used as an educational tool only, not for the diagnosis of disease or other conditions, or in the cure, mitigation, treatment, or prevention of disease.

Waitlist Available
Has No Placebo

Byers Eye Institute

Robert T Chang, MD

Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD

Image of Andover Eye Associates in Andover, United States.

REGN5713 + REGN5715 for Allergic Eye

Any Age
All Sexes
Andover, MA

This study is researching 2 experimental drugs, REGN5713 and REGN5715. The study drugs will be either of these drugs given alone (either REGN5713 or REGN5715) or given together (REGN5713 and REGN5715) to reduce eye allergy signs and symptoms due to birch tree pollen allergy. The aim of the study is to see how safe and effective the study drugs are at lowering eye allergy signs and symptoms compared with placebo. The study will also evaluate whether the combination (REGN5713-5715) has different effectiveness than REGN5713 or REGN5715 alone. The study is looking at several other research questions, including: * What side effects may happen from taking the study drugs * How much of the study drugs is in the blood at different times * Whether the body makes antibodies against the study drugs (which could make the drug less effective or could lead to side effects)

Phase 3
Recruiting

Andover Eye Associates

Clinical Trial Management

Regeneron Pharmaceuticals

Image of MUHC - Montreal General Hospital in Montreal, Canada.

Ustekinumab for Crohn's Disease and Ulcerative Colitis

18+
All Sexes
Montreal, Canada

The goal of this clinical trial is to evaluate whether disease remission can be maintained when biologic therapy is reduced in patients with Crohn"s disease (CD) and ulcerative colitis (UC) taking ustekinumab (UST). The main question it aims to answer is: Can we de-escalate UST subcutaneous dose either from every 4 weeks (Q4) to every 8 weeks (Q8) or every 8 weeks (Q8) to every 12 weeks (Q12) in CD or UC patients in deep remission without loosing their response? Researchers will follow UST blood levels, inflammation markers and intestinal mucosa integrity and to see if UST dose can be reduced while maintaining clinical remission. Participants will: Change UST dosing from Q4 to Q8 or from Q8 to Q12. Visit the clinic once every 12 weeks for checkups and tests.

Phase 4
Recruiting

MUHC - Montreal General Hospital

Janssen Inc.

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Image of The Royal Alexandra Hospital in Edmonton, Canada.

Graft Selection for Glaucoma Surgery

18 - 110
All Sexes
Edmonton, Canada

Glaucoma refers to a group of progressive optic neuropathies that lead to permanent vision loss. Glaucoma is the leading cause of irreversible blindness globally. In 2020, it was estimated to affect 76 million individuals worldwide, with projections indicating this number will rise to 111.8 million by 2040. In Canada, glaucoma affects an estimated 2.7-7.5% of individuals over the age of 50, contributing substantially to the national disease burden. This condition is linked to damage of the optic nerve due to elevated intraocular pressure (IOP; raised eye pressure), which results in the loss of retinal ganglion cells. Therefore, most of the treatments are guided towards reducing the IOP either via using laser, medications or surgery. Glaucoma surgery is typically reserved for cases where IOP remains uncontrolled while on maximum tolerated medical therapy and/or where glaucoma progression warrants surgery. The goal of many glaucoma surgeries is to divert aqueous humor from the anterior chamber to the subconjunctival space, therefore reducing intraocular pressure. The device used for this purpose are the PRESERFLO™ MicroShunt (Glaukos Corporation, Laguna Hills, CA, USA) (the documents will interchangeably use terms "stent" and "shunt" to refer to these devices in the text below). The device is implanted using the ab externo approach to channel fluid from the anterior chamber to the subconjunctival/subtenon space. To reduce postoperative fibrosis and inhibit fibroblast activity that could obstruct flow and lead to device failure, 5-fluorouracil (5-FU) or mitomycin C (MMC) are administered. Additionally, a double-layered closure of conjunctiva and Tenon's is performed to minimize Tenon's migration and blockage of tenon the stents. Despite these measures, stent encapsulation and failure are still too common requiring revisions and bleb needling in 2-20% of cases within the first 12 months of follow-up. This project will involve a series of studies evaluating graft selection in PreserFlo MicroShunt implantation, focusing on donor sclera, cornea, and pericardium as patch graft materials. First, the investigators will conduct a prospective, randomized study comparing clinical outcomes between these graft types. Outcomes of interest will include surgical success rates, post-operative hypotony, tube erosion, conjunctival complications, infection, and overall device longevity. Donor sclera has long been used as a patch graft in glaucoma drainage device surgery and is associated with low erosion rates and reliable long-term results. Corneal tissue is increasingly used due to its transparency and availability through eye banks, with demonstrated safety in ocular surface reconstruction and tube coverage. Pericardium is another durable, biocompatible option, historically applied in both cardiovascular and ocular surgery, and has shown effectiveness as a patch graft in glaucoma drainage implants. This comparison will extend to both primary implantation and revision surgeries, recognizing the high clinical relevance of graft performance in complex cases. Building on these results, the investigators will then perform a cost-effectiveness analysis of graft strategies, incorporating surgical time, post-operative management, complication rates, and need for re-operation. An economic model will be developed to evaluate costs and resource utilization associated with each material, providing valuable data for policy and surgical decision-making. Finally, the investigators will conduct a patient-reported outcome (PRO) study to assess patient comfort and satisfaction with different grafts. Surveys will evaluate domains such as foreign body sensation, cosmesis, and overall satisfaction at key time points (immediate post-operative period, 1 week, 3 weeks, and 3 months). These results will highlight the patient perspective, an often underrepresented but critical factor in surgical innovation. Together, these studies will comprehensively assess graft selection from surgical, economic, and patient-centered perspectives, informing evidence-based practice in glaucoma care.

Waitlist Available
Has No Placebo

The Royal Alexandra Hospital

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